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Items: 1 to 20 of 121

1.

Differential regulation and localization of carboxypeptidase D and carboxypeptidase E in human and mouse β-cells.

Chu KY, Briggs MJ, Albrecht T, Drain PF, Johnson JD.

Islets. 2011 Jul-Aug;3(4):155-65. Epub 2011 Jul 1.

PMID:
21628999
3.

Beta-cell lines derived from transgenic Cpe(fat)/Cpe(fat) mice are defective in carboxypeptidase E and proinsulin processing.

Varlamov O, Fricker LD, Furukawa H, Steiner DF, Langley SH, Leiter EH.

Endocrinology. 1997 Nov;138(11):4883-92.

PMID:
9348219
4.

Trafficking of mutant carboxypeptidase E to secretory granules in a beta-cell line derived from Cpe(fat)/Cpe(fat) mice.

Cawley NX, Rodriguez YM, Maldonado A, Loh YP.

Endocrinology. 2003 Jan;144(1):292-8.

PMID:
12488357
5.
6.

The sorting of proglucagon to secretory granules is mediated by carboxypeptidase E and intrinsic sorting signals.

McGirr R, Guizzetti L, Dhanvantari S.

J Endocrinol. 2013 Apr 15;217(2):229-40. doi: 10.1530/JOE-12-0468. Print 2013 May.

7.

Interaction between secretogranin III and carboxypeptidase E facilitates prohormone sorting within secretory granules.

Hosaka M, Watanabe T, Sakai Y, Kato T, Takeuchi T.

J Cell Sci. 2005 Oct 15;118(Pt 20):4785-95.

8.

Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis.

Jeffrey KD, Alejandro EU, Luciani DS, Kalynyak TB, Hu X, Li H, Lin Y, Townsend RR, Polonsky KS, Johnson JD.

Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8452-7. doi: 10.1073/pnas.0711232105. Epub 2008 Jun 11.

10.

Cloning and expression of Aplysia carboxypeptidase D, a candidate prohormone-processing enzyme.

Fan X, Qian Y, Fricker LD, Akalal DB, Nagle GT.

DNA Cell Biol. 1999 Feb;18(2):121-32.

PMID:
10073571
11.

Developmental changes in opioid peptides and their receptors in Cpe(fat)/Cpe(fat) mice lacking peptide processing enzyme carboxypeptidase E.

Boudarine M, Yegorov O, Sterling-Dubrovsky A, Devi LA, Berman Y.

J Pharmacol Exp Ther. 2002 Dec;303(3):1317-24.

12.
13.

The "go or grow" potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress.

Höring E, Harter PN, Seznec J, Schittenhelm J, Bühring HJ, Bhattacharyya S, von Hattingen E, Zachskorn C, Mittelbronn M, Naumann U.

Acta Neuropathol. 2012 Jul;124(1):83-97. doi: 10.1007/s00401-011-0940-x. Epub 2012 Jan 15.

PMID:
22249620
15.

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity.

Naggert JK, Fricker LD, Varlamov O, Nishina PM, Rouille Y, Steiner DF, Carroll RJ, Paigen BJ, Leiter EH.

Nat Genet. 1995 Jun;10(2):135-42.

PMID:
7663508
16.

The orphan nuclear receptor small heterodimer partner negatively regulates pancreatic beta cell survival and hyperglycemia in multiple low-dose streptozotocin-induced type 1 diabetic mice.

Noh JR, Hwang JH, Kim YH, Kim KS, Gang GT, Kim SW, Kim DK, Shong M, Lee IK, Choi HS, Lee CH.

Int J Biochem Cell Biol. 2013 Aug;45(8):1538-45. doi: 10.1016/j.biocel.2013.05.004. Epub 2013 May 13.

PMID:
23680671
17.

Role of carboxypeptidase E in processing of pro-islet amyloid polypeptide in {beta}-cells.

Marzban L, Soukhatcheva G, Verchere CB.

Endocrinology. 2005 Apr;146(4):1808-17. Epub 2004 Dec 23.

PMID:
15618358
18.

NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion.

Li N, Li B, Brun T, Deffert-Delbouille C, Mahiout Z, Daali Y, Ma XJ, Krause KH, Maechler P.

Diabetes. 2012 Nov;61(11):2842-50. doi: 10.2337/db12-0009. Epub 2012 Aug 28.

19.

Luminal interaction of phogrin with carboxypeptidase E for effective targeting to secretory granules.

Saito N, Takeuchi T, Kawano A, Hosaka M, Hou N, Torii S.

Traffic. 2011 Apr;12(4):499-506. doi: 10.1111/j.1600-0854.2011.01159.x. Epub 2011 Feb 8.

20.

Carboxypeptidase E activity is deficient in mice with the fat mutation. Effect on peptide processing.

Fricker LD, Berman YL, Leiter EH, Devi LA.

J Biol Chem. 1996 Nov 29;271(48):30619-24.

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