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Items: 1 to 20 of 161

1.

FDA-approved drug labeling for the study of drug-induced liver injury.

Chen M, Vijay V, Shi Q, Liu Z, Fang H, Tong W.

Drug Discov Today. 2011 Aug;16(15-16):697-703. doi: 10.1016/j.drudis.2011.05.007. Epub 2011 May 20.

PMID:
21624500
2.

Quantitative structure-activity relationship models for predicting drug-induced liver injury based on FDA-approved drug labeling annotation and using a large collection of drugs.

Chen M, Hong H, Fang H, Kelly R, Zhou G, Borlak J, Tong W.

Toxicol Sci. 2013 Nov;136(1):242-9. doi: 10.1093/toxsci/kft189. Epub 2013 Aug 31.

3.

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W.

PLoS Comput Biol. 2011 Dec;7(12):e1002310. doi: 10.1371/journal.pcbi.1002310. Epub 2011 Dec 15.

4.

Drug hepatotoxicity from a regulatory perspective.

Senior JR.

Clin Liver Dis. 2007 Aug;11(3):507-24, vi. Review.

PMID:
17723917
5.

High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury.

Chen M, Borlak J, Tong W.

Hepatology. 2013 Jul;58(1):388-96. doi: 10.1002/hep.26208. Epub 2013 May 27.

PMID:
23258593
6.

Approaches to the study of drug-induced liver injury.

Fontana RJ.

Clin Pharmacol Ther. 2010 Sep;88(3):416-9. doi: 10.1038/clpt.2010.100. Epub 2010 Jul 21.

PMID:
20664536
7.

Human drug hepatotoxicity: a contemporary clinical perspective.

Assis DN, Navarro VJ.

Expert Opin Drug Metab Toxicol. 2009 May;5(5):463-73. doi: 10.1517/17425250902927386 . Review.

PMID:
19416083
8.

Review article: Drug-induced liver injury--its pathophysiology and evolving diagnostic tools.

Au JS, Navarro VJ, Rossi S.

Aliment Pharmacol Ther. 2011 Jul;34(1):11-20. doi: 10.1111/j.1365-2036.2011.04674.x. Epub 2011 May 3. Review.

9.

Needles in haystacks.

Reuben A.

Am J Gastroenterol. 2007 Nov;102(11):2444-6.

PMID:
17958757
10.

Case definition and phenotype standardization in drug-induced liver injury.

Aithal GP, Watkins PB, Andrade RJ, Larrey D, Molokhia M, Takikawa H, Hunt CM, Wilke RA, Avigan M, Kaplowitz N, Bjornsson E, Daly AK.

Clin Pharmacol Ther. 2011 Jun;89(6):806-15. doi: 10.1038/clpt.2011.58. Epub 2011 May 4. Review.

PMID:
21544079
11.

Mechanisms of drug-induced liver injury.

Holt MP, Ju C.

AAPS J. 2006 Feb 3;8(1):E48-54. Review.

12.

Idiosyncratic drug-induced liver injury: an overview.

Hussaini SH, Farrington EA.

Expert Opin Drug Saf. 2007 Nov;6(6):673-84. Review.

PMID:
17967156
13.

Drug-induced liver injury.

Holt M, Ju C.

Handb Exp Pharmacol. 2010;(196):3-27. doi: 10.1007/978-3-642-00663-0_1. Review.

PMID:
20020257
14.

Drug-induced liver injury and drug development: industry perspective.

Regev A.

Semin Liver Dis. 2014 May;34(2):227-39. doi: 10.1055/s-0034-1375962. Epub 2014 May 31. Review.

PMID:
24879986
15.

Mitochondrial abnormalities--a link to idiosyncratic drug hepatotoxicity?

Boelsterli UA, Lim PL.

Toxicol Appl Pharmacol. 2007 Apr 1;220(1):92-107. Epub 2006 Dec 22. Review.

PMID:
17275868
16.

Drug-induced liver injury: what was new in 2008?

Liss G, Lewis JH.

Expert Opin Drug Metab Toxicol. 2009 Aug;5(8):843-60. doi: 10.1517/17425250903018904. Review.

PMID:
19505188
17.

Mining FDA drug labels using an unsupervised learning technique--topic modeling.

Bisgin H, Liu Z, Fang H, Xu X, Tong W.

BMC Bioinformatics. 2011 Oct 18;12 Suppl 10:S11. doi: 10.1186/1471-2105-12-S10-S11.

18.

Assessment of drug-induced liver injury in clinical practice.

Lucena MI, García-Cortés M, Cueto R, Lopez-Duran J, Andrade RJ.

Fundam Clin Pharmacol. 2008 Apr;22(2):141-58. doi: 10.1111/j.1472-8206.2008.00566.x. Review. Erratum in: Fundam Clin Pharmacol. 2009 Feb;23(1):147.

PMID:
18353109
19.

The application of metabonomics to predict drug-induced liver injury.

O'Connell TM, Watkins PB.

Clin Pharmacol Ther. 2010 Sep;88(3):394-9. doi: 10.1038/clpt.2010.151. Epub 2010 Jul 28. Review.

PMID:
20668441
20.

Review article: drug-induced liver injury in clinical practice.

Björnsson E.

Aliment Pharmacol Ther. 2010 Jul;32(1):3-13. doi: 10.1111/j.1365-2036.2010.04320.x. Epub 2010 Mar 31. Review.

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