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Mammalian Llgl2 is necessary for proper branching morphogenesis during placental development.

Sripathy S, Lee M, Vasioukhin V.

Mol Cell Biol. 2011 Jul;31(14):2920-33. doi: 10.1128/MCB.05431-11. Epub 2011 May 23.


Ott1 (Rbm15) is essential for placental vascular branching morphogenesis and embryonic development of the heart and spleen.

Raffel GD, Chu GC, Jesneck JL, Cullen DE, Bronson RT, Bernard OA, Gilliland DG.

Mol Cell Biol. 2009 Jan;29(2):333-41. doi: 10.1128/MCB.00370-08. Epub 2008 Nov 3.


Barx2 and Fgf10 regulate ocular glands branching morphogenesis by controlling extracellular matrix remodeling.

Tsau C, Ito M, Gromova A, Hoffman MP, Meech R, Makarenkova HP.

Development. 2011 Aug;138(15):3307-17. doi: 10.1242/dev.066241.


The Drosophila tumor suppressor gene lethal(2)giant larvae is required for the emission of the Decapentaplegic signal.

Arquier N, Perrin L, Manfruelli P, Sémériva M.

Development. 2001 Jun;128(12):2209-20.


Requirements of Lgl in cell differentiation and motility during Drosophila ovarian follicular epithelium morphogenesis.

Li Q, Feng S, Yu L, Zhao G, Li M.

Fly (Austin). 2011 Apr-Jun;5(2):81-7. Epub 2011 Apr 1.


The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice.

van Nes J, de Graaff W, Lebrin F, Gerhard M, Beck F, Deschamps J.

Development. 2006 Feb;133(3):419-28. Epub 2006 Jan 5.


The tumor suppressor Lgl1 regulates NMII-A cellular distribution and focal adhesion morphology to optimize cell migration.

Dahan I, Yearim A, Touboul Y, Ravid S.

Mol Biol Cell. 2012 Feb;23(4):591-601. doi: 10.1091/mbc.E11-01-0015. Epub 2012 Jan 4.


Maternal Tgif is required for vascularization of the embryonic placenta.

Bartholin L, Melhuish TA, Powers SE, Goddard-Léon S, Treilleux I, Sutherland AE, Wotton D.

Dev Biol. 2008 Jul 15;319(2):285-97. doi: 10.1016/j.ydbio.2008.04.027. Epub 2008 May 2.


Lethal giant puzzle of Lgl.

Vasioukhin V.

Dev Neurosci. 2006;28(1-2):13-24. Review.


The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo.

Grifoni D, Garoia F, Schimanski CC, Schmitz G, Laurenti E, Galle PR, Pession A, Cavicchi S, Strand D.

Oncogene. 2004 Nov 11;23(53):8688-94.


A Cdh1HA knock-in allele rescues the Cdh1-/- phenotype but shows essential Cdh1 function during placentation.

Stemmler MP, Bedzhov I.

Dev Dyn. 2010 Sep;239(9):2330-44. doi: 10.1002/dvdy.22375.


Early gene expression and morphogenesis of the murine chorioallantoic placenta in vivo and in vitro.

Proctor LK, Dunk C, Baczyk D, Kingdom JC, Adamson SL.

Placenta. 2009 Jan;30(1):96-104. doi: 10.1016/j.placenta.2008.09.014. Epub 2008 Nov 12.


Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis.

Nechiporuk T, Klezovitch O, Nguyen L, Vasioukhin V.

Dev Biol. 2013 May 15;377(2):375-84. doi: 10.1016/j.ydbio.2013.02.019. Epub 2013 Mar 4.


Stability and function of mammalian lethal giant larvae-1 oncoprotein are regulated by the scaffolding protein RanBPM.

Suresh B, Ramakrishna S, Kim YS, Kim SM, Kim MS, Baek KH.

J Biol Chem. 2010 Nov 12;285(46):35340-9. doi: 10.1074/jbc.M110.156836. Epub 2010 Sep 9.


Trophoblast cell-specific carcinoembryonic antigen cell adhesion molecule 9 is not required for placental development or a positive outcome of allotypic pregnancies.

Finkenzeller D, Fischer B, McLaughlin J, Schrewe H, Ledermann B, Zimmermann W.

Mol Cell Biol. 2000 Oct;20(19):7140-5.


Recruitment of 5' Hoxa genes in the allantois is essential for proper extra-embryonic function in placental mammals.

Scotti M, Kmita M.

Development. 2012 Feb;139(4):731-9. doi: 10.1242/dev.075408. Epub 2012 Jan 4.


The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration.

Margagliotti S, Clotman F, Pierreux CE, Beaudry JB, Jacquemin P, Rousseau GG, Lemaigre FP.

Dev Biol. 2007 Nov 15;311(2):579-89. Epub 2007 Sep 16.


Abnormal cerebellar development and Purkinje cell defects in Lgl1-Pax2 conditional knockout mice.

Hou C, Ding L, Zhang J, Jin Y, Sun C, Li Z, Sun X, Zhang T, Zhang A, Li H, Gao J.

Dev Biol. 2014 Nov 1;395(1):167-81. doi: 10.1016/j.ydbio.2014.07.007. Epub 2014 Jul 19.


Oxygen and placental development during the first trimester: implications for the pathophysiology of pre-eclampsia.

Caniggia I, Winter J, Lye SJ, Post M.

Placenta. 2000 Mar-Apr;21 Suppl A:S25-30.


Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells.

Jossin Y, Lee M, Klezovitch O, Kon E, Cossard A, Lien WH, Fernandez TE, Cooper JA, Vasioukhin V.

Dev Cell. 2017 Jun 5;41(5):481-495.e5. doi: 10.1016/j.devcel.2017.05.002. Epub 2017 May 25.


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