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Items: 1 to 20 of 148


Characterization of a novel heat shock protein (Hsp22.5) involved in the pathogenesis of Mycobacterium tuberculosis.

Abomoelak B, Marcus SA, Ward SK, Karakousis PC, Steinberg H, Talaat AM.

J Bacteriol. 2011 Jul;193(14):3497-505. doi: 10.1128/JB.01536-10. Epub 2011 May 20.


mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis.

Abomoelak B, Hoye EA, Chi J, Marcus SA, Laval F, Bannantine JP, Ward SK, Daffé M, Liu HD, Talaat AM.

J Bacteriol. 2009 Oct;191(19):5941-52. doi: 10.1128/JB.00778-09. Epub 2009 Jul 31.


The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages.

Manganelli R, Voskuil MI, Schoolnik GK, Smith I.

Mol Microbiol. 2001 Jul;41(2):423-37.


Mycobacterial bacilli are metabolically active during chronic tuberculosis in murine lungs: insights from genome-wide transcriptional profiling.

Talaat AM, Ward SK, Wu CW, Rondon E, Tavano C, Bannantine JP, Lyons R, Johnston SA.

J Bacteriol. 2007 Jun;189(11):4265-74. Epub 2007 Mar 23.


Dissection of the heat-shock response in Mycobacterium tuberculosis using mutants and microarrays.

Stewart GR, Wernisch L, Stabler R, Mangan JA, Hinds J, Laing KG, Young DB, Butcher PD.

Microbiology. 2002 Oct;148(Pt 10):3129-38.


The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence.

Parish T, Smith DA, Roberts G, Betts J, Stoker NG.

Microbiology. 2003 Jun;149(Pt 6):1423-35.


The transcriptional regulator Rv0485 modulates the expression of a pe and ppe gene pair and is required for Mycobacterium tuberculosis virulence.

Goldstone RM, Goonesekera SD, Bloom BR, Sampson SL.

Infect Immun. 2009 Oct;77(10):4654-67. doi: 10.1128/IAI.01495-08. Epub 2009 Aug 3.


Study of the in vivo role of Mce2R, the transcriptional regulator of mce2 operon in Mycobacterium tuberculosis.

Forrellad MA, Bianco MV, Blanco FC, Nuñez J, Klepp LI, Vazquez CL, Santangelo Mde L, Rocha RV, Soria M, Golby P, Gutierrez MG, Bigi F.

BMC Microbiol. 2013 Sep 5;13:200. doi: 10.1186/1471-2180-13-200.


Deciphering the genes involved in pathogenesis of Mycobacterium tuberculosis.

Singh R, Singh A, Tyagi AK.

Tuberculosis (Edinb). 2005 Sep-Nov;85(5-6):325-35. Epub 2005 Oct 25.


Effects of Mycobacterium tuberculosis Mutant Strain Hsp16.3 Gene on Murine RAW 264.7 Macrophage Autophagy.

Yang L, Zhang C, Zhao Y, Zhao N, Wu P, Zhang H, Shi C.

DNA Cell Biol. 2018 Jan;37(1):7-14. doi: 10.1089/dna.2016.3599. Epub 2017 Oct 25.


Hypervirulent mutant of Mycobacterium tuberculosis resulting from disruption of the mce1 operon.

Shimono N, Morici L, Casali N, Cantrell S, Sidders B, Ehrt S, Riley LW.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15918-23. Epub 2003 Dec 8.


Iron storage proteins are essential for the survival and pathogenesis of Mycobacterium tuberculosis in THP-1 macrophages and the guinea pig model of infection.

Reddy PV, Puri RV, Khera A, Tyagi AK.

J Bacteriol. 2012 Feb;194(3):567-75. doi: 10.1128/JB.05553-11. Epub 2011 Nov 18.


The polyphosphate kinase gene ppk2 is required for Mycobacterium tuberculosis inorganic polyphosphate regulation and virulence.

Chuang YM, Belchis DA, Karakousis PC.

MBio. 2013 May 21;4(3):e00039-13. doi: 10.1128/mBio.00039-13.


The Mycobacterium tuberculosis sigma factor sigmaB is required for full response to cell envelope stress and hypoxia in vitro, but it is dispensable for in vivo growth.

Fontán PA, Voskuil MI, Gomez M, Tan D, Pardini M, Manganelli R, Fattorini L, Schoolnik GK, Smith I.

J Bacteriol. 2009 Sep;191(18):5628-33. doi: 10.1128/JB.00510-09. Epub 2009 Jul 10.


Deletion of the Mycobacterium tuberculosis pknH gene confers a higher bacillary load during the chronic phase of infection in BALB/c mice.

Papavinasasundaram KG, Chan B, Chung JH, Colston MJ, Davis EO, Av-Gay Y.

J Bacteriol. 2005 Aug;187(16):5751-60.


Attenuation of late-stage disease in mice infected by the Mycobacterium tuberculosis mutant lacking the SigF alternate sigma factor and identification of SigF-dependent genes by microarray analysis.

Geiman DE, Kaushal D, Ko C, Tyagi S, Manabe YC, Schroeder BG, Fleischmann RD, Morrison NE, Converse PJ, Chen P, Bishai WR.

Infect Immun. 2004 Mar;72(3):1733-45.


Rv2744c Is a PspA Ortholog That Regulates Lipid Droplet Homeostasis and Nonreplicating Persistence in Mycobacterium tuberculosis.

Armstrong RM, Adams KL, Zilisch JE, Bretl DJ, Sato H, Anderson DM, Zahrt TC.

J Bacteriol. 2016 May 13;198(11):1645-1661. doi: 10.1128/JB.01001-15. Print 2016 Jun 1.


The lpqS knockout mutant of Mycobacterium tuberculosis is attenuated in macrophages.

Sakthi S, Narayanan S.

Microbiol Res. 2013 Aug 25;168(7):407-14. doi: 10.1016/j.micres.2013.02.007. Epub 2013 Apr 3.

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