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Items: 1 to 20 of 76

1.

Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis.

Bruscia EM, Zhang PX, Satoh A, Caputo C, Medzhitov R, Shenoy A, Egan ME, Krause DS.

J Immunol. 2011 Jun 15;186(12):6990-8. doi: 10.4049/jimmunol.1100396. Epub 2011 May 18.

2.

Toll-like receptor 4 is not targeted to the lysosome in cystic fibrosis airway epithelial cells.

Kelly C, Canning P, Buchanan PJ, Williams MT, Brown V, Gruenert DC, Elborn JS, Ennis M, Schock BC.

Am J Physiol Lung Cell Mol Physiol. 2013 Mar 1;304(5):L371-82. doi: 10.1152/ajplung.00372.2011. Epub 2013 Jan 11.

3.

Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice.

Fiorotto R, Scirpo R, Trauner M, Fabris L, Hoque R, Spirli C, Strazzabosco M.

Gastroenterology. 2011 Oct;141(4):1498-508, 1508.e1-5. doi: 10.1053/j.gastro.2011.06.052. Epub 2011 Jun 26.

4.

Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis transmembrane conductance regulator.

Zhang PX, Murray TS, Villella VR, Ferrari E, Esposito S, D'Souza A, Raia V, Maiuri L, Krause DS, Egan ME, Bruscia EM.

J Immunol. 2013 May 15;190(10):5196-206. doi: 10.4049/jimmunol.1201607. Epub 2013 Apr 19.

5.

Toll-like receptor-4 genotype influences the survival of cystic fibrosis mice.

Canale-Zambrano JC, Auger ML, Haston CK.

Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G381-90. doi: 10.1152/ajpgi.00003.2010. Epub 2010 Jun 3.

6.

Innate immune response in CF airway epithelia: hyperinflammatory?

Machen TE.

Am J Physiol Cell Physiol. 2006 Aug;291(2):C218-30. Review.

8.

TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells.

Greene CM, Carroll TP, Smith SG, Taggart CC, Devaney J, Griffin S, O'neill SJ, McElvaney NG.

J Immunol. 2005 Feb 1;174(3):1638-46.

9.

Induction of type I interferon signaling by Pseudomonas aeruginosa is diminished in cystic fibrosis epithelial cells.

Parker D, Cohen TS, Alhede M, Harfenist BS, Martin FJ, Prince A.

Am J Respir Cell Mol Biol. 2012 Jan;46(1):6-13. doi: 10.1165/rcmb.2011-0080OC.

10.

IL-17 primes airway epithelial cells lacking functional Cystic Fibrosis Transmembrane conductance Regulator (CFTR) to increase NOD1 responses.

Roussel L, Rousseau S.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):505-9. doi: 10.1016/j.bbrc.2009.11.088. Epub 2009 Nov 20.

PMID:
19931506
11.

TLR-4-mediated innate immunity is reduced in cystic fibrosis airway cells.

John G, Yildirim AO, Rubin BK, Gruenert DC, Henke MO.

Am J Respir Cell Mol Biol. 2010 Apr;42(4):424-31. doi: 10.1165/rcmb.2008-0408OC. Epub 2009 Jun 5.

PMID:
19502387
12.

Glia maturation factor-γ negatively modulates TLR4 signaling by facilitating TLR4 endocytic trafficking in macrophages.

Aerbajinai W, Lee K, Chin K, Rodgers GP.

J Immunol. 2013 Jun 15;190(12):6093-103. doi: 10.4049/jimmunol.1203048. Epub 2013 May 15.

13.

Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation.

Zhang PX, Cheng J, Zou S, D'Souza AD, Koff JL, Lu J, Lee PJ, Krause DS, Egan ME, Bruscia EM.

Nat Commun. 2015 Feb 10;6:6221. doi: 10.1038/ncomms7221.

14.
15.

Synergism between interleukin (IL)-17 and Toll-like receptor 2 and 4 signals to induce IL-8 expression in cystic fibrosis airway epithelial cells.

Mizunoe S, Shuto T, Suzuki S, Matsumoto C, Watanabe K, Ueno-Shuto K, Suico MA, Onuki K, Gruenert DC, Kai H.

J Pharmacol Sci. 2012;118(4):512-20. Epub 2012 Mar 29.

16.

Inflammation in cystic fibrosis airways: relationship to increased bacterial adherence.

Scheid P, Kempster L, Griesenbach U, Davies JC, Dewar A, Weber PP, Colledge WH, Evans MJ, Geddes DM, Alton EW.

Eur Respir J. 2001 Jan;17(1):27-35.

18.

Cystic fibrosis transmembrane conductance regulator does not affect neutrophil migration across cystic fibrosis airway epithelial monolayers.

Pizurki L, Morris MA, Chanson M, Solomon M, Pavirani A, Bouchardy I, Suter S.

Am J Pathol. 2000 Apr;156(4):1407-16. Erratum in: Am J Pathol 2000 Oct;157(4):1413.

19.

Effects of cystic fibrosis transmembrane conductance regulator and DeltaF508CFTR on inflammatory response, ER stress, and Ca2+ of airway epithelia.

Hybiske K, Fu Z, Schwarzer C, Tseng J, Do J, Huang N, Machen TE.

Am J Physiol Lung Cell Mol Physiol. 2007 Nov;293(5):L1250-60. Epub 2007 Sep 7.

20.

Transient receptor potential canonical channel 6 links Ca2+ mishandling to cystic fibrosis transmembrane conductance regulator channel dysfunction in cystic fibrosis.

Antigny F, Norez C, Dannhoffer L, Bertrand J, Raveau D, Corbi P, Jayle C, Becq F, Vandebrouck C.

Am J Respir Cell Mol Biol. 2011 Jan;44(1):83-90. doi: 10.1165/rcmb.2009-0347OC. Epub 2010 Mar 4.

PMID:
20203293

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