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Items: 1 to 20 of 136

1.

TRPM3 is a nociceptor channel involved in the detection of noxious heat.

Vriens J, Owsianik G, Hofmann T, Philipp SE, Stab J, Chen X, Benoit M, Xue F, Janssens A, Kerselaers S, Oberwinkler J, Vennekens R, Gudermann T, Nilius B, Voets T.

Neuron. 2011 May 12;70(3):482-94. doi: 10.1016/j.neuron.2011.02.051.

2.

Primidone inhibits TRPM3 and attenuates thermal nociception in vivo.

Krügel U, Straub I, Beckmann H, Schaefer M.

Pain. 2017 May;158(5):856-867. doi: 10.1097/j.pain.0000000000000846.

3.

Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo.

Straub I, Krügel U, Mohr F, Teichert J, Rizun O, Konrad M, Oberwinkler J, Schaefer M.

Mol Pharmacol. 2013 Nov;84(5):736-50. doi: 10.1124/mol.113.086843. Epub 2013 Sep 4.

4.

Citrus fruit and fabacea secondary metabolites potently and selectively block TRPM3.

Straub I, Mohr F, Stab J, Konrad M, Philipp SE, Oberwinkler J, Schaefer M.

Br J Pharmacol. 2013 Apr;168(8):1835-50. doi: 10.1111/bph.12076.

5.

Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release.

Held K, Kichko T, De Clercq K, Klaassen H, Van Bree R, Vanherck JC, Marchand A, Reeh PW, Chaltin P, Voets T, Vriens J.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1363-72. doi: 10.1073/pnas.1419845112. Epub 2015 Mar 2.

6.

Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia.

Ro JY, Lee JS, Zhang Y.

Pain. 2009 Aug;144(3):270-7. doi: 10.1016/j.pain.2009.04.021. Epub 2009 May 22.

7.

Sodium channel Na(v)1.7 is essential for lowering heat pain threshold after burn injury.

Shields SD, Cheng X, Uçeyler N, Sommer C, Dib-Hajj SD, Waxman SG.

J Neurosci. 2012 Aug 8;32(32):10819-32. doi: 10.1523/JNEUROSCI.0304-12.2012.

8.

Stimulation-dependent gating of TRPM3 channel in planar lipid bilayers.

Uchida K, Demirkhanyan L, Asuthkar S, Cohen A, Tominaga M, Zakharian E.

FASEB J. 2016 Mar;30(3):1306-16. doi: 10.1096/fj.15-281576. Epub 2015 Dec 9.

9.

AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties.

Gavva NR, Tamir R, Qu Y, Klionsky L, Zhang TJ, Immke D, Wang J, Zhu D, Vanderah TW, Porreca F, Doherty EM, Norman MH, Wild KD, Bannon AW, Louis JC, Treanor JJ.

J Pharmacol Exp Ther. 2005 Apr;313(1):474-84. Epub 2004 Dec 22.

10.

The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation.

da Costa DS, Meotti FC, Andrade EL, Leal PC, Motta EM, Calixto JB.

Pain. 2010 Mar;148(3):431-7. doi: 10.1016/j.pain.2009.12.002. Epub 2009 Dec 28.

PMID:
20056530
11.

Impaired nociception and inflammatory pain sensation in mice lacking the prokineticin receptor PKR1: focus on interaction between PKR1 and the capsaicin receptor TRPV1 in pain behavior.

Negri L, Lattanzi R, Giannini E, Colucci M, Margheriti F, Melchiorri P, Vellani V, Tian H, De Felice M, Porreca F.

J Neurosci. 2006 Jun 21;26(25):6716-27.

12.
13.

Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels.

Bang S, Yoo S, Yang TJ, Cho H, Hwang SW.

Pain. 2011 May;152(5):1156-64. doi: 10.1016/j.pain.2011.01.044. Epub 2011 Feb 24.

PMID:
21353389
14.

Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole.

Meseguer V, Karashima Y, Talavera K, D'Hoedt D, Donovan-Rodríguez T, Viana F, Nilius B, Voets T.

J Neurosci. 2008 Jan 16;28(3):576-86. doi: 10.1523/JNEUROSCI.4772-07.2008.

15.
16.

RNA interference-mediated knock-down of transient receptor potential vanilloid 1 prevents forepaw inflammatory hyperalgesia in rat.

Kasama S, Kawakubo M, Suzuki T, Nishizawa T, Ishida A, Nakayama J.

Eur J Neurosci. 2007 May;25(10):2956-63. Epub 2007 May 17.

PMID:
17509082
17.

Inhibitor kappaB Kinase beta deficiency in primary nociceptive neurons increases TRP channel sensitivity.

Bockhart V, Constantin CE, Häussler A, Wijnvoord N, Kanngiesser M, Myrczek T, Pickert G, Popp L, Sobotzik JM, Pasparakis M, Kuner R, Geisslinger G, Schultz C, Kress M, Tegeder I.

J Neurosci. 2009 Oct 14;29(41):12919-29. doi: 10.1523/JNEUROSCI.1496-09.2009.

18.

Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain.

Caires R, Luis E, Taberner FJ, Fernandez-Ballester G, Ferrer-Montiel A, Balazs EA, Gomis A, Belmonte C, de la Peña E.

Nat Commun. 2015 Aug 27;6:8095. doi: 10.1038/ncomms9095.

19.

Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia.

Btesh J, Fischer MJM, Stott K, McNaughton PA.

J Neurosci. 2013 May 22;33(21):9184-9193. doi: 10.1523/JNEUROSCI.4991-12.2013. Erratum in: J Neurosci. 2015 May 27;35(21):8377.

20.

Transcriptome analysis of trigeminal ganglia following masseter muscle inflammation in rats.

Chung MK, Park J, Asgar J, Ro JY.

Mol Pain. 2016 Oct 4;12. pii: 1744806916668526. Print 2016.

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