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Items: 1 to 20 of 108

1.

Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL-17 secretion.

Lluis A, Schedel M, Liu J, Illi S, Depner M, von Mutius E, Kabesch M, Schaub B.

J Allergy Clin Immunol. 2011 Jun;127(6):1587-94.e6. doi: 10.1016/j.jaci.2011.03.015. Epub 2011 May 4.

PMID:
21546069
2.

Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels.

Schedel M, Michel S, Gaertner VD, Toncheva AA, Depner M, Binia A, Schieck M, Rieger MT, Klopp N, von Berg A, Bufe A, Laub O, Rietschel E, Heinzmann A, Simma B, Vogelberg C, Genuneit J, Illig T, Kabesch M.

J Allergy Clin Immunol. 2015 Oct;136(4):893-903.e14. doi: 10.1016/j.jaci.2015.03.014. Epub 2015 Apr 28.

PMID:
25930191
3.

Genetic variants of 17q21 are associated with childhood-onset asthma and related phenotypes in a northeastern Han Chinese population: a case-control study.

Yu X, Yu C, Ren Z, Deng Y, Song J, Zhang H, Zhou H.

Tissue Antigens. 2014 May;83(5):330-6. doi: 10.1111/tan.12342. Epub 2014 Mar 21.

PMID:
24649901
4.

Association of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han population.

Fang Q, Zhao H, Wang A, Gong Y, Liu Q.

BMC Med Genet. 2011 Oct 11;12:133. doi: 10.1186/1471-2350-12-133.

5.

Asthma and atopy are associated with chromosome 17q21 markers in Chinese children.

Leung TF, Sy HY, Ng MC, Chan IH, Wong GW, Tang NL, Waye MM, Lam CW.

Allergy. 2009 Apr;64(4):621-8. doi: 10.1111/j.1398-9995.2008.01873.x. Epub 2009 Jan 27.

PMID:
19175592
6.

Relationship between the 17q21 locus and adult asthma in a Czech population.

Hrdlickova B, Holla LI.

Hum Immunol. 2011 Oct;72(10):921-5. doi: 10.1016/j.humimm.2011.07.309. Epub 2011 Aug 1.

PMID:
21843571
7.

Effect of 17q21 variants and smoking exposure in early-onset asthma.

Bouzigon E, Corda E, Aschard H, Dizier MH, Boland A, Bousquet J, Chateigner N, Gormand F, Just J, Le Moual N, Scheinmann P, Siroux V, Vervloet D, Zelenika D, Pin I, Kauffmann F, Lathrop M, Demenais F.

N Engl J Med. 2008 Nov 6;359(19):1985-94. doi: 10.1056/NEJMoa0806604. Epub 2008 Oct 15.

8.

ORMDL3--guilt by association?

Wjst M.

Clin Exp Allergy. 2008 Oct;38(10):1579-81. doi: 10.1111/j.1365-2222.2008.03086.x. Epub 2008 Aug 26.

PMID:
18754760
9.

Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma.

Berce V, Kozmus CE, Potočnik U.

Pharmacogenomics J. 2013 Dec;13(6):523-9. doi: 10.1038/tpj.2012.36. Epub 2012 Sep 18.

PMID:
22986918
10.

Variants in the 17q21 asthma susceptibility locus are associated with allergic rhinitis in the Japanese population.

Tomita K, Sakashita M, Hirota T, Tanaka S, Masuyama K, Yamada T, Fujieda S, Miyatake A, Hizawa N, Kubo M, Nakamura Y, Tamari M.

Allergy. 2013 Jan;68(1):92-100. doi: 10.1111/all.12066. Epub 2012 Nov 12.

PMID:
23157251
11.

Chromosome 17q21 Genes ORMDL3 and GSDMB in Asthma and Immune Diseases.

Das S, Miller M, Broide DH.

Adv Immunol. 2017;135:1-52. doi: 10.1016/bs.ai.2017.06.001. Epub 2017 Jul 19. Review.

PMID:
28826527
12.

Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis.

Andiappan AK, Sio YY, Lee B, Suri BK, Matta SA, Lum J, Foo S, Koh G, Liu J, Zolezzi F, Poidinger M, Wang de Y, Rotzschke O, Chew FT.

J Allergy Clin Immunol. 2016 Mar;137(3):758-66.e3. doi: 10.1016/j.jaci.2015.08.038. Epub 2015 Oct 23.

PMID:
26483175
13.

17q21 variants modify the association between early respiratory infections and asthma.

Smit LA, Bouzigon E, Pin I, Siroux V, Monier F, Aschard H, Bousquet J, Gormand F, Just J, Le Moual N, Nadif R, Scheinmann P, Vervloet D, Lathrop M, Demenais F, Kauffmann F; EGEA Cooperative Group.

Eur Respir J. 2010 Jul;36(1):57-64. doi: 10.1183/09031936.00154509. Epub 2009 Dec 23.

14.

[Genome-wide association study of bronchial asthma in the Volga-Ural region of Russia].

Karunas AS, Iunusbaev BB, Fedorova IuIu, Gimalova GF, Ramazanova NN, Gur'eva LL, Mukhtarova LA, Zagidullin ShZ, Etkina EI, Khusnutdinova EK.

Mol Biol (Mosk). 2011 Nov-Dec;45(6):992-1003. Russian.

PMID:
22295569
15.

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma.

Moffatt MF, Kabesch M, Liang L, Dixon AL, Strachan D, Heath S, Depner M, von Berg A, Bufe A, Rietschel E, Heinzmann A, Simma B, Frischer T, Willis-Owen SA, Wong KC, Illig T, Vogelberg C, Weiland SK, von Mutius E, Abecasis GR, Farrall M, Gut IG, Lathrop GM, Cookson WO.

Nature. 2007 Jul 26;448(7152):470-3. Epub 2007 Jul 4.

16.

Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

Ferreira MA, McRae AF, Medland SE, Nyholt DR, Gordon SD, Wright MJ, Henders AK, Madden PA, Visscher PM, Wray NR, Heath AC, Montgomery GW, Duffy DL, Martin NG.

Eur J Hum Genet. 2011 Apr;19(4):458-64. doi: 10.1038/ejhg.2010.191. Epub 2010 Dec 8. Erratum in: Eur J Hum Genet. 2011 Oct;19(10):1109.

17.

Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma.

Wu H, Romieu I, Sienra-Monge JJ, Li H, del Rio-Navarro BE, London SJ.

Allergy. 2009 Apr;64(4):629-35. doi: 10.1111/j.1398-9995.2008.01912.x. Epub 2008 Dec 30.

18.

Effects of a 17q21 chromosome gene variant, tobacco smoke and furred pets on infant wheeze.

Bräuner EV, Loft S, Raaschou-Nielsen O, Vogel U, Andersen PS, Sørensen M.

Genes Immun. 2012 Jan;13(1):94-7. doi: 10.1038/gene.2011.51. Epub 2011 Jul 28.

PMID:
21796154
19.

Mechanisms elevating ORMDL3 expression in recurrent wheeze patients: role of Ets-1, p300 and CREB.

Jin R, Xu HG, Yuan WX, Zhuang LL, Liu LF, Jiang L, Zhu LH, Liu JY, Zhou GP.

Int J Biochem Cell Biol. 2012 Jul;44(7):1174-83. doi: 10.1016/j.biocel.2012.04.007. Epub 2012 Apr 23. Erratum in: Int J Biochem Cell Biol. 2012 Nov;44(11):2094.

PMID:
22546552
20.

Genome-wide association studies for discovery of genes involved in asthma.

Akhabir L, Sandford AJ.

Respirology. 2011 Apr;16(3):396-406. doi: 10.1111/j.1440-1843.2011.01939.x. Review.

PMID:
21276132

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