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Items: 1 to 20 of 103

1.

Generation of hematopoietic humanized mice in the newborn BALB/c-Rag2null Il2rγnull mouse model: a multivariable optimization approach.

Lang J, Weiss N, Freed BM, Torres RM, Pelanda R.

Clin Immunol. 2011 Jul;140(1):102-16. doi: 10.1016/j.clim.2011.04.002. Epub 2011 Apr 14.

2.

Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.

Brehm MA, Cuthbert A, Yang C, Miller DM, DiIorio P, Laning J, Burzenski L, Gott B, Foreman O, Kavirayani A, Herlihy M, Rossini AA, Shultz LD, Greiner DL.

Clin Immunol. 2010 Apr;135(1):84-98. doi: 10.1016/j.clim.2009.12.008. Epub 2010 Jan 21.

3.

Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.

Strowig T, Rongvaux A, Rathinam C, Takizawa H, Borsotti C, Philbrick W, Eynon EE, Manz MG, Flavell RA.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13218-23. doi: 10.1073/pnas.1109769108. Epub 2011 Jul 25.

4.

NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models.

Ito M, Kobayashi K, Nakahata T.

Curr Top Microbiol Immunol. 2008;324:53-76. Review.

PMID:
18481452
5.

Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice.

Gorantla S, Sneller H, Walters L, Sharp JG, Pirruccello SJ, West JT, Wood C, Dewhurst S, Gendelman HE, Poluektova L.

J Virol. 2007 Mar;81(6):2700-12. Epub 2006 Dec 20.

6.

Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes.

Akkina R, Berges BK, Palmer BE, Remling L, Neff CP, Kuruvilla J, Connick E, Folkvord J, Gagliardi K, Kassu A, Akkina SR.

PLoS One. 2011;6(6):e20169. doi: 10.1371/journal.pone.0020169. Epub 2011 Jun 14.

7.

Experimental model for the study of the human immune system: production and monitoring of "human immune system" Rag2-/-gamma c-/- mice.

Legrand N, Weijer K, Spits H.

Methods Mol Biol. 2008;415:65-82. doi: 10.1007/978-1-59745-570-1_4.

PMID:
18370148
8.

Creation of "humanized" mice to study human immunity.

Pearson T, Greiner DL, Shultz LD.

Curr Protoc Immunol. 2008 May;Chapter 15:Unit 15.21. doi: 10.1002/0471142735.im1521s81.

9.

Dengue virus infection and immune response in humanized RAG2(-/-)gamma(c)(-/-) (RAG-hu) mice.

Kuruvilla JG, Troyer RM, Devi S, Akkina R.

Virology. 2007 Dec 5;369(1):143-52. Epub 2007 Aug 16.

10.

Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice.

Brehm MA, Bortell R, Diiorio P, Leif J, Laning J, Cuthbert A, Yang C, Herlihy M, Burzenski L, Gott B, Foreman O, Powers AC, Greiner DL, Shultz LD.

Diabetes. 2010 Sep;59(9):2265-70. doi: 10.2337/db10-0323. Epub 2010 Jun 22.

11.

Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.

Hasgur S, Aryee KE, Shultz LD, Greiner DL, Brehm MA.

Methods Mol Biol. 2016;1438:67-78. doi: 10.1007/978-1-4939-3661-8_4.

12.

Mucosal transmission of R5 and X4 tropic HIV-1 via vaginal and rectal routes in humanized Rag2-/- gammac -/- (RAG-hu) mice.

Berges BK, Akkina SR, Folkvord JM, Connick E, Akkina R.

Virology. 2008 Apr 10;373(2):342-51. doi: 10.1016/j.virol.2007.11.020. Epub 2008 Jan 18.

13.

Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease.

Pino S, Brehm MA, Covassin-Barberis L, King M, Gott B, Chase TH, Wagner J, Burzenski L, Foreman O, Greiner DL, Shultz LD.

Methods Mol Biol. 2010;602:105-17. doi: 10.1007/978-1-60761-058-8_7.

14.

Long term human reconstitution and immune aging in NOD-Rag (-)-γ chain (-) mice.

Harris DT, Badowski M.

Immunobiology. 2014 Feb;219(2):131-7. doi: 10.1016/j.imbio.2013.08.013. Epub 2013 Sep 5.

15.

Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2Rγ(null) humanized mice.

Billerbeck E, Barry WT, Mu K, Dorner M, Rice CM, Ploss A.

Blood. 2011 Mar 17;117(11):3076-86. doi: 10.1182/blood-2010-08-301507. Epub 2011 Jan 20.

16.

Co-transplantation of human fetal thymus, bone and CD34(+) cells into young adult immunodeficient NOD/SCID IL2Rγ(null) mice optimizes humanized mice that mount adaptive antibody responses.

Chung YS, Son JK, Choi B, Joo SY, Lee YS, Park JB, Moon H, Kim TJ, Kim SH, Hong S, Chang J, Kang MS, Kim SJ.

Clin Immunol. 2015 Apr;157(2):156-65. doi: 10.1016/j.clim.2015.02.005. Epub 2015 Feb 25.

PMID:
25725428
17.

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice.

Ishikawa F, Yasukawa M, Lyons B, Yoshida S, Miyamoto T, Yoshimoto G, Watanabe T, Akashi K, Shultz LD, Harada M.

Blood. 2005 Sep 1;106(5):1565-73. Epub 2005 May 26.

18.

Transplantation of human spleen into immunodeficient NOD/SCID IL2Rγ(null) mice generates humanized mice that improve functional B cell development.

Chung YS, Son JK, Choi B, Park JB, Chang J, Kim SJ.

Clin Immunol. 2015 Dec;161(2):308-15. doi: 10.1016/j.clim.2015.09.001. Epub 2015 Sep 7.

PMID:
26360254
19.

Long-term human CD34+ stem cell-engrafted nonobese diabetic/SCID/IL-2R gamma(null) mice show impaired CD8+ T cell maintenance and a functional arrest of immature NK cells.

André MC, Erbacher A, Gille C, Schmauke V, Goecke B, Hohberger A, Mang P, Wilhelm A, Mueller I, Herr W, Lang P, Handgretinger R, Hartwig UF.

J Immunol. 2010 Sep 1;185(5):2710-20. doi: 10.4049/jimmunol.1000583. Epub 2010 Jul 28.

20.

Development of functional human immune system with the transplantations of human fetal liver/thymus tissues and expanded hematopoietic stem cells in RAG2-/-gamma(c)-/- MICE.

Joo SY, Choi BK, Kang MJ, Jung DY, Park KS, Park JB, Choi GS, Joh J, Kwon CH, Jung GO, Lee SK, Kim SJ.

Transplant Proc. 2009 Jun;41(5):1885-90. doi: 10.1016/j.transproceed.2009.02.074.

PMID:
19545750

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