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Origin of bistability underlying mammalian cell cycle entry.

Yao G, Tan C, West M, Nevins JR, You L.

Mol Syst Biol. 2011 Apr 26;7:485. doi: 10.1038/msb.2011.19.


A bistable Rb-E2F switch underlies the restriction point.

Yao G, Lee TJ, Mori S, Nevins JR, You L.

Nat Cell Biol. 2008 Apr;10(4):476-82. doi: 10.1038/ncb1711. Epub 2008 Mar 23.


Lamina-associated polypeptide 2alpha regulates cell cycle progression and differentiation via the retinoblastoma-E2F pathway.

Dorner D, Vlcek S, Foeger N, Gajewski A, Makolm C, Gotzmann J, Hutchison CJ, Foisner R.

J Cell Biol. 2006 Apr 10;173(1):83-93.


Systematic reverse engineering of network topologies: a case study of resettable bistable cellular responses.

Mondal D, Dougherty E, Mukhopadhyay A, Carbo A, Yao G, Xing J.

PLoS One. 2014 Aug 29;9(8):e105833. doi: 10.1371/journal.pone.0105833. eCollection 2014.


Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes.

Sdek P, Zhao P, Wang Y, Huang CJ, Ko CY, Butler PC, Weiss JN, Maclellan WR.

J Cell Biol. 2011 Aug 8;194(3):407-23. doi: 10.1083/jcb.201012049.


Phase portraits of the proliferation-quiescence decision.

Zhang T.

Sci Signal. 2013 Dec 10;6(305):pe37. doi: 10.1126/scisignal.2004891.


Dynamical behaviors of Rb-E2F pathway including negative feedback loops involving miR449.

Yan F, Liu H, Hao J, Liu Z.

PLoS One. 2012;7(9):e43908. doi: 10.1371/journal.pone.0043908. Epub 2012 Sep 18.


The Retinoblastoma pathway regulates stem cell proliferation in freshwater planarians.

Zhu SJ, Pearson BJ.

Dev Biol. 2013 Jan 15;373(2):442-52. doi: 10.1016/j.ydbio.2012.10.025. Epub 2012 Nov 1.


Geminin is targeted for repression by the retinoblastoma tumor suppressor pathway through intragenic E2F sites.

Markey M, Siddiqui H, Knudsen ES.

J Biol Chem. 2004 Jul 9;279(28):29255-62. Epub 2004 Apr 14.


Integrin subunits alpha5 and alpha6 regulate cell cycle by modulating the chk1 and Rb/E2F pathways to affect breast cancer metastasis.

Wang Y, Shenouda S, Baranwal S, Rathinam R, Jain P, Bao L, Hazari S, Dash S, Alahari SK.

Mol Cancer. 2011 Jul 13;10:84. doi: 10.1186/1476-4598-10-84.


Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase.

Lieman JH, Worley LA, Harbour JW.

J Biol Chem. 2005 Mar 18;280(11):10484-90. Epub 2005 Jan 7.


Regulation of modular Cyclin and CDK feedback loops by an E2F transcription oscillator in the mammalian cell cycle.

Lavi O, Ginsberg D, Louzoun Y.

Math Biosci Eng. 2011 Apr;8(2):445-61. doi: 10.3934/mbe.2011.8.445.


Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest.

Sheahan S, Bellamy CO, Dunbar DR, Harrison DJ, Prost S.

BMC Cancer. 2007 Nov 19;7:215.


Regulation of RB transcription in vivo by RB family members.

Burkhart DL, Ngai LK, Roake CM, Viatour P, Thangavel C, Ho VM, Knudsen ES, Sage J.

Mol Cell Biol. 2010 Apr;30(7):1729-45. doi: 10.1128/MCB.00952-09. Epub 2010 Jan 25.


The RB/E2F pathway and regulation of RNA processing.

Ahlander J, Bosco G.

Biochem Biophys Res Commun. 2009 Jul 3;384(3):280-3. doi: 10.1016/j.bbrc.2009.04.107. Epub 2009 May 3. Review.


Regulation of miR106b cluster through the RB pathway: mechanism and functional targets.

Thangavel C, Boopathi E, Ertel A, Lim M, Addya S, Fortina P, Witkiewicz AK, Knudsen ES.

Cell Cycle. 2013 Jan 1;12(1):98-111. doi: 10.4161/cc.23029. Epub 2012 Dec 19.


The THAP-zinc finger protein THAP1 regulates endothelial cell proliferation through modulation of pRB/E2F cell-cycle target genes.

Cayrol C, Lacroix C, Mathe C, Ecochard V, Ceribelli M, Loreau E, Lazar V, Dessen P, Mantovani R, Aguilar L, Girard JP.

Blood. 2007 Jan 15;109(2):584-94. Epub 2006 Sep 26.

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