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Items: 1 to 20 of 138

1.

TOFA (5-tetradecyl-oxy-2-furoic acid) reduces fatty acid synthesis, inhibits expression of AR, neuropilin-1 and Mcl-1 and kills prostate cancer cells independent of p53 status.

Guseva NV, Rokhlin OW, Glover RA, Cohen MB.

Cancer Biol Ther. 2011 Jul 1;12(1):80-5. doi: 10.4161/cbt.12.1.15721.

PMID:
21525791
2.

KN-93 inhibits androgen receptor activity and induces cell death irrespective of p53 and Akt status in prostate cancer.

Rokhlin OW, Guseva NV, Taghiyev AF, Glover RA, Cohen MB.

Cancer Biol Ther. 2010 Feb;9(3):224-35.

PMID:
20023417
3.

Small-interfering RNA-induced androgen receptor silencing leads to apoptotic cell death in prostate cancer.

Liao X, Tang S, Thrasher JB, Griebling TL, Li B.

Mol Cancer Ther. 2005 Apr;4(4):505-15.

4.

AT-101 (R-(-)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model.

McGregor N, Patel L, Craig M, Weidner S, Wang S, Pienta KJ.

J Cell Biochem. 2010 Aug 1;110(5):1187-94. doi: 10.1002/jcb.22633.

5.

TGF-beta signaling and androgen receptor status determine apoptotic cross-talk in human prostate cancer cells.

Zhu ML, Partin JV, Bruckheimer EM, Strup SE, Kyprianou N.

Prostate. 2008 Feb 15;68(3):287-95. doi: 10.1002/pros.20698.

PMID:
18163430
7.

Mechanisms of prostate cancer cell survival after inhibition of AR expression.

Cohen MB, Rokhlin OW.

J Cell Biochem. 2009 Feb 15;106(3):363-71. doi: 10.1002/jcb.22022. Review.

PMID:
19115258
8.

Interruption of nuclear factor kappaB signaling by the androgen receptor facilitates 12-O-tetradecanoylphorbolacetate-induced apoptosis in androgen-sensitive prostate cancer LNCaP cells.

Altuwaijri S, Lin HK, Chuang KH, Lin WJ, Yeh S, Hanchett LA, Rahman MM, Kang HY, Tsai MY, Zhang Y, Yang L, Chang C.

Cancer Res. 2003 Nov 1;63(21):7106-12.

9.

Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells.

Zhou W, Simpson PJ, McFadden JM, Townsend CA, Medghalchi SM, Vadlamudi A, Pinn ML, Ronnett GV, Kuhajda FP.

Cancer Res. 2003 Nov 1;63(21):7330-7.

10.

Antiandrogen-induced cell death in LNCaP human prostate cancer cells.

Lee EC, Zhan P, Schallhom R, Packman K, Tenniswood M.

Cell Death Differ. 2003 Jul;10(7):761-71.

11.

Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation.

Marrocco DL, Tilley WD, Bianco-Miotto T, Evdokiou A, Scher HI, Rifkind RA, Marks PA, Richon VM, Butler LM.

Mol Cancer Ther. 2007 Jan;6(1):51-60.

12.
13.

Androgen receptor-dependent regulation of Bcl-xL expression: Implication in prostate cancer progression.

Sun A, Tang J, Hong Y, Song J, Terranova PF, Thrasher JB, Svojanovsky S, Wang HG, Li B.

Prostate. 2008 Mar 1;68(4):453-61. doi: 10.1002/pros.20723.

PMID:
18196538
14.

Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence.

Unni E, Sun S, Nan B, McPhaul MJ, Cheskis B, Mancini MA, Marcelli M.

Cancer Res. 2004 Oct 1;64(19):7156-68.

15.

Apoptosis induction by a novel anti-prostate cancer compound, BMD188 (a fatty acid-containing hydroxamic acid), requires the mitochondrial respiratory chain.

Joshi B, Li L, Taffe BG, Zhu Z, Wahl S, Tian H, Ben-Josef E, Taylor JD, Porter AT, Tang DG.

Cancer Res. 1999 Sep 1;59(17):4343-55.

16.
17.

Androgenic up-regulation of androgen receptor cDNA expression in androgen-independent prostate cancer cells.

Dai JL, Maiorino CA, Gkonos PJ, Burnstein KL.

Steroids. 1996 Sep;61(9):531-9.

PMID:
8883219
18.

Arachidonic acid activation of intratumoral steroid synthesis during prostate cancer progression to castration resistance.

Locke JA, Guns ES, Lehman ML, Ettinger S, Zoubeidi A, Lubik A, Margiotti K, Fazli L, Adomat H, Wasan KM, Gleave ME, Nelson CC.

Prostate. 2010 Feb 15;70(3):239-51. doi: 10.1002/pros.21057.

PMID:
19790237
20.

Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor.

Heisler LE, Evangelou A, Lew AM, Trachtenberg J, Elsholtz HP, Brown TJ.

Mol Cell Endocrinol. 1997 Jan 3;126(1):59-73.

PMID:
9027364
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