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Items: 1 to 20 of 219

1.

AMPK and mTOR coordinate the regulation of Ulk1 and mammalian autophagy initiation.

Shang L, Wang X.

Autophagy. 2011 Aug;7(8):924-6. Epub 2011 Aug 1.

PMID:
21521945
2.

The serine/threonine kinase ULK1 is a target of multiple phosphorylation events.

Bach M, Larance M, James DE, Ramm G.

Biochem J. 2011 Dec 1;440(2):283-91. doi: 10.1042/BJ20101894.

PMID:
21819378
3.

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

Kim J, Kundu M, Viollet B, Guan KL.

Nat Cell Biol. 2011 Feb;13(2):132-41. doi: 10.1038/ncb2152. Epub 2011 Jan 23.

4.

The role of the Atg1/ULK1 complex in autophagy regulation.

Mizushima N.

Curr Opin Cell Biol. 2010 Apr;22(2):132-9. doi: 10.1016/j.ceb.2009.12.004. Epub 2010 Jan 6. Review.

PMID:
20056399
5.

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR.

Egan D, Kim J, Shaw RJ, Guan KL.

Autophagy. 2011 Jun;7(6):643-4. Epub 2011 Jun 1.

6.

Regulation of the autophagy initiating kinase ULK1 by nutrients: roles of mTORC1 and AMPK.

Kim J, Guan KL.

Cell Cycle. 2011 May 1;10(9):1337-8. doi: 10.4161/cc.10.9.15291. Epub 2011 Mar 15.

PMID:
21403467
7.

Role of ULK-FIP200 complex in mammalian autophagy: FIP200, a counterpart of yeast Atg17?

Hara T, Mizushima N.

Autophagy. 2009 Jan;5(1):85-7. Epub 2009 Jan 13.

PMID:
18981720
8.

Role of an intrinsically disordered conformation in AMPK-mediated phosphorylation of ULK1 and regulation of autophagy.

Khan SH, Kumar R.

Mol Biosyst. 2012 Jan;8(1):91-6. doi: 10.1039/c1mb05265a. Epub 2011 Aug 18. Review.

PMID:
21853163
9.

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy.

Mercer CA, Kaliappan A, Dennis PB.

Autophagy. 2009 Jul;5(5):649-62. Epub 2009 Jul 20.

PMID:
19287211
10.

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.

Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X.

J Biol Chem. 2009 May 1;284(18):12297-305. doi: 10.1074/jbc.M900573200. Epub 2009 Mar 3.

11.

The association of AMPK with ULK1 regulates autophagy.

Lee JW, Park S, Takahashi Y, Wang HG.

PLoS One. 2010 Nov 3;5(11):e15394. doi: 10.1371/journal.pone.0015394.

12.

Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK.

Shang L, Chen S, Du F, Li S, Zhao L, Wang X.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4788-93. doi: 10.1073/pnas.1100844108. Epub 2011 Mar 7.

13.

The ULK1 complex: sensing nutrient signals for autophagy activation.

Wong PM, Puente C, Ganley IG, Jiang X.

Autophagy. 2013 Feb 1;9(2):124-37. doi: 10.4161/auto.23323. Epub 2013 Jan 7. Review.

14.

Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks.

Alers S, Löffler AS, Wesselborg S, Stork B.

Mol Cell Biol. 2012 Jan;32(1):2-11. doi: 10.1128/MCB.06159-11. Epub 2011 Oct 24. Review.

15.

Ulk1-mediated phosphorylation of AMPK constitutes a negative regulatory feedback loop.

Löffler AS, Alers S, Dieterle AM, Keppeler H, Franz-Wachtel M, Kundu M, Campbell DG, Wesselborg S, Alessi DR, Stork B.

Autophagy. 2011 Jul;7(7):696-706. Epub 2011 Jul 1.

PMID:
21460634
16.

AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization.

Mack HI, Zheng B, Asara JM, Thomas SM.

Autophagy. 2012 Aug;8(8):1197-214. doi: 10.4161/auto.20586. Epub 2012 Aug 1.

17.

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway.

Vucicevic L, Misirkic M, Janjetovic K, Vilimanovich U, Sudar E, Isenovic E, Prica M, Harhaji-Trajkovic L, Kravic-Stevovic T, Bumbasirevic V, Trajkovic V.

Autophagy. 2011 Jan;7(1):40-50. Epub 2011 Jan 1.

PMID:
20980833
18.

Computational analysis of an autophagy/translation switch based on mutual inhibition of MTORC1 and ULK1.

Szymańska P, Martin KR, MacKeigan JP, Hlavacek WS, Lipniacki T.

PLoS One. 2015 Mar 11;10(3):e0116550. doi: 10.1371/journal.pone.0116550. eCollection 2015.

19.

AMPK -> ULK1 -> autophagy.

Roach PJ.

Mol Cell Biol. 2011 Aug;31(15):3082-4. doi: 10.1128/MCB.05565-11. Epub 2011 May 31. No abstract available.

20.

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, Guan JL, Oshiro N, Mizushima N.

Mol Biol Cell. 2009 Apr;20(7):1981-91. doi: 10.1091/mbc.E08-12-1248. Epub 2009 Feb 11.

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