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Characterization of the expression of cytokeratins 5, 8, and 14 in mouse thymic epithelial cells during thymus regeneration following acute thymic involution.

Lee EN, Park JK, Lee JR, Oh SO, Baek SY, Kim BS, Yoon S.

Anat Cell Biol. 2011 Mar;44(1):14-24. doi: 10.5115/acb.2011.44.1.14. Epub 2011 Mar 31.


Cytokeratin (CK5, CK8, CK14) expression and presence of progenitor stem cells in human fetal thymuses.

Gupta R, Gupta T, Kaur H, Sehgal S, Aggarwal A, Kapoor K, Sharma A, Sahni D, Singla S.

Clin Anat. 2016 Sep;29(6):711-7. doi: 10.1002/ca.22736. Epub 2016 Jun 13.


Adult thymic epithelial cell (TEC) progenitors and TEC stem cells: Models and mechanisms for TEC development and maintenance.

Hamazaki Y.

Eur J Immunol. 2015 Nov;45(11):2985-93. doi: 10.1002/eji.201545844. Epub 2015 Sep 30. Review.


Regenerative capacity of adult cortical thymic epithelial cells.

Rode I, Boehm T.

Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3463-8. doi: 10.1073/pnas.1118823109. Epub 2012 Feb 13.


Regeneration of the adult thymus is preceded by the expansion of K5+K8+ epithelial cell progenitors and by increased expression of Trp63, cMyc and Tcf3 transcription factors in the thymic stroma.

Popa I, Zubkova I, Medvedovic M, Romantseva T, Mostowski H, Boyd R, Zaitseva M.

Int Immunol. 2007 Nov;19(11):1249-60. Epub 2007 Sep 6.


Thymic epithelial progenitor cells and thymus regeneration: an update.

Zhang L, Sun L, Zhao Y.

Cell Res. 2007 Jan;17(1):50-5. Review.


Serial progression of cortical and medullary thymic epithelial microenvironments.

Alves NL, Takahama Y, Ohigashi I, Ribeiro AR, Baik S, Anderson G, Jenkinson WE.

Eur J Immunol. 2014 Jan;44(1):16-22. doi: 10.1002/eji.201344110. Epub 2013 Dec 4. Review. Erratum in: Eur J Immunol. 2014 Jul;44(7):2197.


Thymic stromal cell subsets for T cell development.

Nitta T, Suzuki H.

Cell Mol Life Sci. 2016 Mar;73(5):1021-37. doi: 10.1007/s00018-015-2107-8. Epub 2016 Jan 29. Review.


Thymic epithelial β-catenin is required for adult thymic homeostasis and function.

Liang CC, You LR, Yen JJ, Liao NS, Yang-Yen HF, Chen CM.

Immunol Cell Biol. 2013 Sep;91(8):511-23. doi: 10.1038/icb.2013.34. Epub 2013 Jul 16.


Thymocyte selection regulates the homeostasis of IL-7-expressing thymic cortical epithelial cells in vivo.

Ribeiro AR, Rodrigues PM, Meireles C, Di Santo JP, Alves NL.

J Immunol. 2013 Aug 1;191(3):1200-9. doi: 10.4049/jimmunol.1203042. Epub 2013 Jun 21.


Expression of nerve growth factor is upregulated in the rat thymic epithelial cells during thymus regeneration following acute thymic involution.

Lee HW, Kim SM, Shim NR, Bae SK, Jung IG, Kwak JY, Kim BS, Kim JB, Moon JO, Chung JS, Yoon S.

Regul Pept. 2007 Jun 7;141(1-3):86-95. Epub 2007 Jan 10.


DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.

Osada M, Jardine L, Misir R, Andl T, Millar SE, Pezzano M.

PLoS One. 2010 Feb 8;5(2):e9062. doi: 10.1371/journal.pone.0009062.


Medullary thymic epithelial stem cells: role in thymic epithelial cell maintenance and thymic involution.

Hamazaki Y, Sekai M, Minato N.

Immunol Rev. 2016 May;271(1):38-55. doi: 10.1111/imr.12412. Review.


Intermediate expression of CCRL1 reveals novel subpopulations of medullary thymic epithelial cells that emerge in the postnatal thymus.

Ribeiro AR, Meireles C, Rodrigues PM, Alves NL.

Eur J Immunol. 2014 Oct;44(10):2918-24. doi: 10.1002/eji.201444585. Epub 2014 Sep 5. Erratum in: Eur J Immunol. 2014 Dec;44(12):3768.


Development and developmental potential of cortical thymic epithelial cells.

Ohigashi I, Kozai M, Takahama Y.

Immunol Rev. 2016 May;271(1):10-22. doi: 10.1111/imr.12404. Review.


Adult Thymic Medullary Epithelium Is Maintained and Regenerated by Lineage-Restricted Cells Rather Than Bipotent Progenitors.

Ohigashi I, Zuklys S, Sakata M, Mayer CE, Hamazaki Y, Minato N, Hollander GA, Takahama Y.

Cell Rep. 2015 Nov 17;13(7):1432-1443. doi: 10.1016/j.celrep.2015.10.012. Epub 2015 Nov 5.


Thymic Epithelial Cells Induced from Pluripotent Stem Cells by a Three-Dimensional Spheroid Culture System Regenerates Functional T Cells in Nude Mice.

Okabe M, Ito S, Nishio N, Tanaka Y, Isobe K.

Cell Reprogram. 2015 Oct;17(5):368-75. doi: 10.1089/cell.2015.0006. Epub 2015 Sep 8.


FSP1(+) fibroblast subpopulation is essential for the maintenance and regeneration of medullary thymic epithelial cells.

Sun L, Sun C, Liang Z, Li H, Chen L, Luo H, Zhang H, Ding P, Sun X, Qin Z, Zhao Y.

Sci Rep. 2015 Oct 8;5:14871. doi: 10.1038/srep14871.


Alterations of Thymic Epithelial Cells in Lipopolysaccharide-induced Neonatal Thymus Involution.

Zhou YJ, Peng H, Chen Y, Liu YL.

Chin Med J (Engl). 2016 Jan 5;129(1):59-65. doi: 10.4103/0366-6999.172577.

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