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Items: 1 to 20 of 108

1.

Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans.

Budatha M, Roshanravan S, Zheng Q, Weislander C, Chapman SL, Davis EC, Starcher B, Word RA, Yanagisawa H.

J Clin Invest. 2011 May;121(5):2048-59. doi: 10.1172/JCI45636.

2.

Effect of vaginal distention on elastic fiber synthesis and matrix degradation in the vaginal wall: potential role in the pathogenesis of pelvic organ prolapse.

Rahn DD, Acevedo JF, Word RA.

Am J Physiol Regul Integr Comp Physiol. 2008 Oct;295(4):R1351-8. doi: 10.1152/ajpregu.90447.2008.

3.

Dysregulation of protease and protease inhibitors in a mouse model of human pelvic organ prolapse.

Budatha M, Silva S, Montoya TI, Suzuki A, Shah-Simpson S, Wieslander CK, Yanagisawa M, Word RA, Yanagisawa H.

PLoS One. 2013;8(2):e56376. doi: 10.1371/journal.pone.0056376.

4.

Expression of extracellular matrix-remodeling proteins is altered in vaginal tissue of premenopausal women with severe pelvic organ prolapse.

Alarab M, Kufaishi H, Lye S, Drutz H, Shynlova O.

Reprod Sci. 2014 Jun;21(6):704-15. doi: 10.1177/1933719113512529.

5.

[Expression and significance of elastin and fibulin-5 in anterior vaginal tissue of women with pelvic organ prolapse].

Li B, Zhang QF, Lin XY, Chen LL, Ouyang L, Zhang SL.

Zhonghua Fu Chan Ke Za Zhi. 2009 Jul;44(7):514-7. Chinese.

PMID:
19957551
6.

Pelvic organ prolapse in fibulin-5 knockout mice: pregnancy-induced changes in elastic fiber homeostasis in mouse vagina.

Drewes PG, Yanagisawa H, Starcher B, Hornstra I, Csiszar K, Marinis SI, Keller P, Word RA.

Am J Pathol. 2007 Feb;170(2):578-89.

7.

Quantification of pelvic organ prolapse in mice: vaginal protease activity precedes increased MOPQ scores in fibulin 5 knockout mice.

Wieslander CK, Rahn DD, McIntire DD, Acevedo JF, Drewes PG, Yanagisawa H, Word RA.

Biol Reprod. 2009 Mar;80(3):407-14. doi: 10.1095/biolreprod.108.072900.

8.

Elastogenesis in the vaginal wall and pelvic-organ prolapse.

Connell KA.

N Engl J Med. 2011 Jun 16;364(24):2356-8. doi: 10.1056/NEJMcibr1104976. No abstract available.

PMID:
21675895
9.

Failure of pelvic organ support in mice deficient in fibulin-3.

Rahn DD, Acevedo JF, Roshanravan S, Keller PW, Davis EC, Marmorstein LY, Word RA.

Am J Pathol. 2009 Jan;174(1):206-15. doi: 10.2353/ajpath.2009.080212.

10.

Fibulin-5: two for the price of one maintaining pelvic support.

Northington GM.

J Clin Invest. 2011 May;121(5):1688-91. doi: 10.1172/JCI57438.

11.

Differential expression profiling of matrix metalloproteinases and tissue inhibitors of metalloproteinases in females with or without pelvic organ prolapse.

Wang X, Li Y, Chen J, Guo X, Guan H, Li C.

Mol Med Rep. 2014 Oct;10(4):2004-8. doi: 10.3892/mmr.2014.2467.

PMID:
25110112
12.

Functional characteristics of vaginal fibroblastic cells from premenopausal women with pelvic organ prolapse.

Ruiz-Zapata AM, Kerkhof MH, Zandieh-Doulabi B, Brölmann HA, Smit TH, Helder MN.

Mol Hum Reprod. 2014 Nov;20(11):1135-43. doi: 10.1093/molehr/gau078.

13.

[Connective tissue and prolapse genesis].

Tremollieres F.

Gynecol Obstet Fertil. 2010 Jun;38(6):388-93. doi: 10.1016/j.gyobfe.2010.04.005. Review. French.

PMID:
20576547
14.

Decreased expression of elastin, fibulin-5 and lysyl oxidase-like 1 in the uterosacral ligaments of postmenopausal women with pelvic organ prolapse.

Zhao BH, Zhou JH.

J Obstet Gynaecol Res. 2012 Jun;38(6):925-31. doi: 10.1111/j.1447-0756.2011.01814.x.

PMID:
22487196
15.

Transforming growth factor β1 and extracellular matrix protease expression in the uterosacral ligaments of patients with and without pelvic organ prolapse.

Leegant A, Zuckerwise LC, Downing K, Brouwer-Visser J, Zhu C, Cossio MJ, Strube F, Xie X, Banks E, Huang GS.

Female Pelvic Med Reconstr Surg. 2015 Jan-Feb;21(1):53-8. doi: 10.1097/SPV.0000000000000130.

16.

Identifying distinct nanoscopic features of native collagen fibrils towards early diagnosis of pelvic organ prolapse.

Kim T, Sridharan I, Ma Y, Zhu B, Chi N, Kobak W, Rotmensch J, Schieber JD, Wang R.

Nanomedicine. 2016 Apr;12(3):667-75. doi: 10.1016/j.nano.2015.11.006.

PMID:
26656625
17.

Fibulin-5 (FBLN5) gene polymorphism is associated with pelvic organ prolapse.

Khadzhieva MB, Kamoeva SV, Chumachenko AG, Ivanova AV, Volodin IV, Vladimirov IS, Abilev SK, Salnikova LE.

Maturitas. 2014 Aug;78(4):287-92. doi: 10.1016/j.maturitas.2014.05.003.

PMID:
24917111
18.

Loss of fibulin-5 binding to beta1 integrins inhibits tumor growth by increasing the level of ROS.

Schluterman MK, Chapman SL, Korpanty G, Ozumi K, Fukai T, Yanagisawa H, Brekken RA.

Dis Model Mech. 2010 May-Jun;3(5-6):333-42. doi: 10.1242/dmm.003707.

19.

Vasoactive intestinal peptide expression in the vaginal anterior wall of patients with pelvic organ prolapse.

Hu JM, Cheng X, Wang L, Zhu JN, Zhou LH.

Taiwan J Obstet Gynecol. 2013 Jun;52(2):233-40. doi: 10.1016/j.tjog.2013.04.014.

20.

Changes in tissue composition of the vaginal wall of premenopausal women with prolapse.

Kerkhof MH, Ruiz-Zapata AM, Bril H, Bleeker MC, Belien JA, Stoop R, Helder MN.

Am J Obstet Gynecol. 2014 Feb;210(2):168.e1-9. doi: 10.1016/j.ajog.2013.10.881.

PMID:
24184181
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