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Items: 1 to 20 of 139

1.

Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2.

Fitzpatrick AM, Stephenson ST, Hadley GR, Burwell L, Penugonda M, Simon DM, Hansen J, Jones DP, Brown LA.

J Allergy Clin Immunol. 2011 Jun;127(6):1604-11. doi: 10.1016/j.jaci.2011.03.031. Epub 2011 Apr 22.

2.

Disruption of Nrf2/ARE signaling impairs antioxidant mechanisms and promotes cell degradation pathways in aged skeletal muscle.

Miller CJ, Gounder SS, Kannan S, Goutam K, Muthusamy VR, Firpo MA, Symons JD, Paine R 3rd, Hoidal JR, Rajasekaran NS.

Biochim Biophys Acta. 2012 Jun;1822(6):1038-50. doi: 10.1016/j.bbadis.2012.02.007. Epub 2012 Feb 15.

3.

Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure.

Kim HJ, Vaziri ND.

Am J Physiol Renal Physiol. 2010 Mar;298(3):F662-71. doi: 10.1152/ajprenal.00421.2009. Epub 2009 Dec 9.

4.

Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells.

Yang SP, Yang XZ, Cao GP.

Mol Med Rep. 2015 Jul;12(1):1145-50. doi: 10.3892/mmr.2015.3490. Epub 2015 Mar 13.

PMID:
25776802
5.

Alterations in the Nrf2-Keap1 signaling pathway and its downstream target genes in rat brain under stress.

Djordjevic J, Djordjevic A, Adzic M, Mitic M, Lukic I, Radojcic MB.

Brain Res. 2015 Mar 30;1602:20-31. doi: 10.1016/j.brainres.2015.01.010. Epub 2015 Jan 15.

PMID:
25598205
6.

Mechanism of the Nrf2/Keap1/ARE signaling system.

Tkachev VO, Menshchikova EB, Zenkov NK.

Biochemistry (Mosc). 2011 Apr;76(4):407-22. Review.

PMID:
21585316
7.
8.

Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells.

Kode A, Rajendrasozhan S, Caito S, Yang SR, Megson IL, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2008 Mar;294(3):L478-88. Epub 2007 Dec 27.

9.

Caveolin-1 inhibits expression of antioxidant enzymes through direct interaction with nuclear erythroid 2 p45-related factor-2 (Nrf2).

Li W, Liu H, Zhou JS, Cao JF, Zhou XB, Choi AM, Chen ZH, Shen HH.

J Biol Chem. 2012 Jun 15;287(25):20922-30. doi: 10.1074/jbc.M112.352336. Epub 2012 Apr 30.

10.

Lymphocyte levels of redox-sensitive transcription factors and antioxidative enzymes as indicators of pro-oxidative state in depressive patients.

Lukic I, Mitic M, Djordjevic J, Tatalovic N, Bozovic N, Soldatovic I, Mihaljevic M, Pavlovic Z, Radojcic MB, Maric NP, Adzic M.

Neuropsychobiology. 2014;70(1):1-9. doi: 10.1159/000362841. Epub 2014 Aug 21.

PMID:
25170744
11.

Age-related cataracts: homocysteine coupled endoplasmic reticulum stress and suppression of Nrf2-dependent antioxidant protection.

Elanchezhian R, Palsamy P, Madson CJ, Lynch DW, Shinohara T.

Chem Biol Interact. 2012 Oct 25;200(1):1-10. doi: 10.1016/j.cbi.2012.08.017. Epub 2012 Sep 1.

12.

Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis.

Stępkowski TM, Kruszewski MK.

Free Radic Biol Med. 2011 May 1;50(9):1186-95. doi: 10.1016/j.freeradbiomed.2011.01.033. Epub 2011 Feb 2.

PMID:
21295136
13.

Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2.

Singh A, Rangasamy T, Thimmulappa RK, Lee H, Osburn WO, Brigelius-Flohé R, Kensler TW, Yamamoto M, Biswal S.

Am J Respir Cell Mol Biol. 2006 Dec;35(6):639-50. Epub 2006 Jun 22. Erratum in: Am J Respir Cell Mol Biol. 2007 May;36(5):642.

14.

Acute exposure to 3-methylcholanthrene induces hepatic oxidative stress via activation of the Nrf2/ARE signaling pathway in mice.

Jin Y, Miao W, Lin X, Pan X, Ye Y, Xu M, Fu Z.

Environ Toxicol. 2014 Dec;29(12):1399-408. doi: 10.1002/tox.21870. Epub 2013 May 27.

PMID:
23712962
15.

Glutathione redox control of asthma: from molecular mechanisms to therapeutic opportunities.

Fitzpatrick AM, Jones DP, Brown LA.

Antioxid Redox Signal. 2012 Jul 15;17(2):375-408. doi: 10.1089/ars.2011.4198. Epub 2012 Mar 9. Review.

16.

Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.

Sun Z, Zhang S, Chan JY, Zhang DD.

Mol Cell Biol. 2007 Sep;27(18):6334-49. Epub 2007 Jul 16.

17.

Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling.

Lee HH, Park SA, Almazari I, Kim EH, Na HK, Surh YJ.

Arch Biochem Biophys. 2010 Sep 1;501(1):142-50. doi: 10.1016/j.abb.2010.06.011. Epub 2010 Jun 15.

PMID:
20558128
18.

Time course of Keap1-Nrf2 pathway expression after experimental intracerebral haemorrhage: correlation with brain oedema and neurological deficit.

Shang H, Yang D, Zhang W, Li T, Ren X, Wang X, Zhao W.

Free Radic Res. 2013 May;47(5):368-75. doi: 10.3109/10715762.2013.778403. Epub 2013 Mar 21.

PMID:
23438812
19.

Airway glutathione homeostasis is altered in children with severe asthma: evidence for oxidant stress.

Fitzpatrick AM, Teague WG, Holguin F, Yeh M, Brown LA; Severe Asthma Research Program.

J Allergy Clin Immunol. 2009 Jan;123(1):146-152.e8. doi: 10.1016/j.jaci.2008.10.047.

20.

Nuclear factor erythroid 2-like 2 (Nrf2) expression in end-stage liver disease.

Kurzawski M, Dziedziejko V, Urasińska E, Post M, Wójcicki M, Miętkiewski J, Droździk M.

Environ Toxicol Pharmacol. 2012 Jul;34(1):87-95. doi: 10.1016/j.etap.2012.03.001. Epub 2012 Mar 11.

PMID:
22459801

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