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Items: 1 to 20 of 45

1.

The role of microRNA-150 as a tumor suppressor in malignant lymphoma.

Watanabe A, Tagawa H, Yamashita J, Teshima K, Nara M, Iwamoto K, Kume M, Kameoka Y, Takahashi N, Nakagawa T, Shimizu N, Sawada K.

Leukemia. 2011 Aug;25(8):1324-34. doi: 10.1038/leu.2011.81. Epub 2011 Apr 19.

PMID:
21502955
2.

Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia.

Yamanaka Y, Tagawa H, Takahashi N, Watanabe A, Guo YM, Iwamoto K, Yamashita J, Saitoh H, Kameoka Y, Shimizu N, Ichinohasama R, Sawada K.

Blood. 2009 Oct 8;114(15):3265-75. doi: 10.1182/blood-2009-06-222794. Epub 2009 Jul 29.

3.

MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation.

Lee KH, Chen YL, Yeh SD, Hsiao M, Lin JT, Goan YG, Lu PJ.

Oncogene. 2009 Sep 24;28(38):3360-70. doi: 10.1038/onc.2009.192. Epub 2009 Jul 13.

PMID:
19597470
4.

Replacement treatment with microRNA-143 and -145 induces synergistic inhibition of the growth of human bladder cancer cells by regulating PI3K/Akt and MAPK signaling pathways.

Noguchi S, Yasui Y, Iwasaki J, Kumazaki M, Yamada N, Naito S, Akao Y.

Cancer Lett. 2013 Jan 28;328(2):353-61. doi: 10.1016/j.canlet.2012.10.017. Epub 2012 Oct 24.

PMID:
23104321
5.

Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101.

Ferreira AC, Robaina MC, Rezende LM, Severino P, Klumb CE.

Ann Hematol. 2014 Jun;93(6):983-93. doi: 10.1007/s00277-014-2021-4. Epub 2014 Feb 28.

PMID:
24577510
6.

MiR-124 suppresses cell proliferation in hepatocellular carcinoma by targeting PIK3CA.

Lang Q, Ling C.

Biochem Biophys Res Commun. 2012 Sep 21;426(2):247-52. doi: 10.1016/j.bbrc.2012.08.075. Epub 2012 Aug 23.

PMID:
22940133
7.

Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.

Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA.

Oncogene. 2007 Aug 16;26(38):5606-14. Epub 2007 Mar 12.

PMID:
17353907
8.

The tumor suppressive microRNA miR-218 targets the mTOR component Rictor and inhibits AKT phosphorylation in oral cancer.

Uesugi A, Kozaki K, Tsuruta T, Furuta M, Morita K, Imoto I, Omura K, Inazawa J.

Cancer Res. 2011 Sep 1;71(17):5765-78. doi: 10.1158/0008-5472.CAN-11-0368. Epub 2011 Jul 27.

9.

MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met.

Yan D, Zhou X, Chen X, Hu DN, Dong XD, Wang J, Lu F, Tu L, Qu J.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1559-65. doi: 10.1167/iovs.08-2681. Epub 2008 Nov 21.

PMID:
19029026
10.

miR-203 reverses chemoresistance in p53-mutated colon cancer cells through downregulation of Akt2 expression.

Li J, Chen Y, Zhao J, Kong F, Zhang Y.

Cancer Lett. 2011 May 1;304(1):52-9. doi: 10.1016/j.canlet.2011.02.003. Epub 2011 Feb 26.

PMID:
21354697
11.

Quantitative proteomics reveals that miR-155 regulates the PI3K-AKT pathway in diffuse large B-cell lymphoma.

Huang X, Shen Y, Liu M, Bi C, Jiang C, Iqbal J, McKeithan TW, Chan WC, Ding SJ, Fu K.

Am J Pathol. 2012 Jul;181(1):26-33. doi: 10.1016/j.ajpath.2012.03.013. Epub 2012 May 18.

12.

MiRNA-451 plays a role as tumor suppressor in human glioma cells.

Nan Y, Han L, Zhang A, Wang G, Jia Z, Yang Y, Yue X, Pu P, Zhong Y, Kang C.

Brain Res. 2010 Nov 4;1359:14-21. doi: 10.1016/j.brainres.2010.08.074. Epub 2010 Sep 18.

PMID:
20816946
13.

Reduced expression of the tumor suppressor PHLPP1 enhances the antiapoptotic B-cell receptor signal in chronic lymphocytic leukemia B-cells.

Suljagic M, Laurenti L, Tarnani M, Alam M, Malek SN, Efremov DG.

Leukemia. 2010 Dec;24(12):2063-71. doi: 10.1038/leu.2010.201. Epub 2010 Sep 23.

PMID:
20861921
14.

Epigenetics, microRNAs, and carcinogenesis: functional role of microRNA-137 in uveal melanoma.

Chen X, Wang J, Shen H, Lu J, Li C, Hu DN, Dong XD, Yan D, Tu L.

Invest Ophthalmol Vis Sci. 2011 Mar 2;52(3):1193-9. doi: 10.1167/iovs.10-5272.

PMID:
21051724
15.

Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway.

Meng Q, Xia C, Fang J, Rojanasakul Y, Jiang BH.

Cell Signal. 2006 Dec;18(12):2262-71. Epub 2006 Jun 2.

PMID:
16839745
17.

MicroRNA HSA-miR-125a-5p induces apoptosis by activating p53 in lung cancer cells.

Jiang L, Huang Q, Chang J, Wang E, Qiu X.

Exp Lung Res. 2011 Sep;37(7):387-98. doi: 10.3109/01902148.2010.492068. Epub 2011 Jul 21.

PMID:
21777146
18.

Tumor-suppressive mir-663 gene induces mitotic catastrophe growth arrest in human gastric cancer cells.

Pan J, Hu H, Zhou Z, Sun L, Peng L, Yu L, Sun L, Liu J, Yang Z, Ran Y.

Oncol Rep. 2010 Jul;24(1):105-12.

PMID:
20514450
19.

Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen.

Wang Q, Li DC, Li ZF, Liu CX, Xiao YM, Zhang B, Li XD, Zhao J, Chen LP, Xing XM, Tang SF, Lin YC, Lai YD, Yang P, Zeng JL, Xiao Q, Zeng XW, Lin ZN, Zhuang ZX, Zhuang SM, Chen W.

Oncogene. 2011 Sep 8;30(36):3875-86. doi: 10.1038/onc.2011.103. Epub 2011 Apr 4.

PMID:
21460851
20.

Interleukin-2 induces NF-kappaB activation through BCL10 and affects its subcellular localization in natural killer lymphoma cells.

Chan KK, Shen L, Au WY, Yuen HF, Wong KY, Guo T, Wong ML, Shimizu N, Tsuchiyama J, Kwong YL, Liang RH, Srivastava G.

J Pathol. 2010 Jun;221(2):164-74. doi: 10.1002/path.2699.

PMID:
20235165

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