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Items: 1 to 20 of 100

1.

Efficient Intracellular Delivery of a Pro-Apoptotic Peptide With A pH-Responsive Carrier.

Albarran B, Hoffman AS, Stayton PS.

React Funct Polym. 2011 Mar 1;71(3):261-265.

2.

A TAT-streptavidin fusion protein directs uptake of biotinylated cargo into mammalian cells.

Albarran B, To R, Stayton PS.

Protein Eng Des Sel. 2005 Mar;18(3):147-52. Epub 2005 Apr 8.

PMID:
15820981
3.

Internalization of novel non-viral vector TAT-streptavidin into human cells.

Rinne J, Albarran B, Jylhävä J, Ihalainen TO, Kankaanpää P, Hytönen VP, Stayton PS, Kulomaa MS, Vihinen-Ranta M.

BMC Biotechnol. 2007 Jan 2;7:1.

4.

Intracellular delivery of a proapoptotic peptide via conjugation to a RAFT synthesized endosomolytic polymer.

Duvall CL, Convertine AJ, Benoit DS, Hoffman AS, Stayton PS.

Mol Pharm. 2010 Apr 5;7(2):468-76. doi: 10.1021/mp9002267.

5.

The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.

Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.

J Biol Chem. 2011 Mar 18;286(11):9382-92. doi: 10.1074/jbc.M110.203638. Epub 2010 Dec 9.

6.

Intracellular delivery and trafficking dynamics of a lymphoma-targeting antibody-polymer conjugate.

Berguig GY, Convertine AJ, Shi J, Palanca-Wessels MC, Duvall CL, Pun SH, Press OW, Stayton PS.

Mol Pharm. 2012 Dec 3;9(12):3506-14. doi: 10.1021/mp300338s. Epub 2012 Nov 5.

7.
8.

Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X(L).

Lama D, Sankararamakrishnan R.

J Comput Aided Mol Des. 2011 May;25(5):413-26. doi: 10.1007/s10822-011-9428-y. Epub 2011 Apr 27.

PMID:
21523491
10.

A comparison of two strategies for affinity maturation of a BH3 peptide toward pro-survival Bcl-2 proteins.

Zhang S, Long A, Link AJ.

ACS Synth Biol. 2012 Mar 16;1(3):89-98. doi: 10.1021/sb200002m. Epub 2011 Oct 7.

PMID:
23651073
11.

Relationship between helix stability and binding affinities: molecular dynamics simulations of Bfl-1/A1-binding pro-apoptotic BH3 peptide helices in explicit solvent.

Modi V, Lama D, Sankararamakrishnan R.

J Biomol Struct Dyn. 2013;31(1):65-77. doi: 10.1080/07391102.2012.691363. Epub 2012 Jul 18.

PMID:
22803956
12.

Enzyme-Cleavable Polymeric Micelles for the Intracellular Delivery of Proapoptotic Peptides.

Kern HB, Srinivasan S, Convertine AJ, Hockenbery D, Press OW, Stayton PS.

Mol Pharm. 2017 May 1;14(5):1450-1459. doi: 10.1021/acs.molpharmaceut.6b01178. Epub 2017 Mar 30.

PMID:
28277671
13.

Sequence and helicity requirements for the proapoptotic activity of Bax BH3 peptides.

Shangary S, Oliver CL, Tillman TS, Cascio M, Johnson DE.

Mol Cancer Ther. 2004 Nov;3(11):1343-54.

14.

A novel system enhancing the endosomal escapes of peptides promotes Bak BH3 peptide inducing apoptosis in lung cancer A549 cells.

Lin N, Zheng W, Li L, Liu H, Wang T, Wang P, Ma X.

Target Oncol. 2014 Jun;9(2):163-70. doi: 10.1007/s11523-013-0282-9. Epub 2013 Jun 6.

PMID:
23740403
15.

Regulation of apoptosis by BH3 domains in a cell-free system.

Cosulich SC, Worrall V, Hedge PJ, Green S, Clarke PR.

Curr Biol. 1997 Dec 1;7(12):913-20.

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Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.

Willis SN, Chen L, Dewson G, Wei A, Naik E, Fletcher JI, Adams JM, Huang DC.

Genes Dev. 2005 Jun 1;19(11):1294-305. Epub 2005 May 18.

19.

Amphipathic tail-anchoring peptide and Bcl-2 homology domain-3 (BH3) peptides from Bcl-2 family proteins induce apoptosis through different mechanisms.

Ko JK, Choi KH, Peng J, He F, Zhang Z, Weisleder N, Lin J, Ma J.

J Biol Chem. 2011 Mar 18;286(11):9038-48. doi: 10.1074/jbc.M110.198457. Epub 2010 Dec 28.

20.

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