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Items: 1 to 20 of 100

1.

Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer.

Steine EJ, Ehrich M, Bell GW, Raj A, Reddy S, van Oudenaarden A, Jaenisch R, Linhart HG.

J Clin Invest. 2011 May;121(5):1748-52. doi: 10.1172/JCI43169. Epub 2011 Apr 1.

2.

Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation.

Hagemann S, Kuck D, Stresemann C, Prinz F, Brueckner B, Mund C, Mumberg D, Sommer A.

PLoS One. 2012;7(5):e36125. doi: 10.1371/journal.pone.0036125. Epub 2012 May 1.

3.

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing.

Linhart HG, Lin H, Yamada Y, Moran E, Steine EJ, Gokhale S, Lo G, Cantu E, Ehrich M, He T, Meissner A, Jaenisch R.

Genes Dev. 2007 Dec 1;21(23):3110-22.

4.

Global identification of genes targeted by DNMT3b for epigenetic silencing in lung cancer.

Teneng I, Tellez CS, Picchi MA, Klinge DM, Yingling CM, Snider AM, Liu Y, Belinsky SA.

Oncogene. 2015 Jan 29;34(5):621-30. doi: 10.1038/onc.2013.580. Epub 2014 Jan 27.

PMID:
24469050
5.

HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors.

Ghoshal K, Motiwala T, Claus R, Yan P, Kutay H, Datta J, Majumder S, Bai S, Majumder A, Huang T, Plass C, Jacob ST.

PLoS One. 2010 Apr 29;5(4):e10338. doi: 10.1371/journal.pone.0010338.

6.
7.

DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells.

McGough JM, Yang D, Huang S, Georgi D, Hewitt SM, Röcken C, Tänzer M, Ebert MP, Liu K.

Mol Cancer Res. 2008 Dec;6(12):1841-51. doi: 10.1158/1541-7786.MCR-08-0280.

8.

Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes.

Takahashi M, Kamei Y, Ehara T, Yuan X, Suganami T, Takai-Igarashi T, Hatada I, Ogawa Y.

Biochem Biophys Res Commun. 2013 May 17;434(4):873-8. doi: 10.1016/j.bbrc.2013.04.041. Epub 2013 Apr 20.

PMID:
23611774
9.

Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases.

Paz MF, Wei S, Cigudosa JC, Rodriguez-Perales S, Peinado MA, Huang TH, Esteller M.

Hum Mol Genet. 2003 Sep 1;12(17):2209-19. Epub 2003 Jul 15.

PMID:
12915469
10.

Inhibition of intestinal tumor formation by deletion of the DNA methyltransferase 3a.

Weis B, Schmidt J, Maamar H, Raj A, Lin H, Tóth C, Riedmann K, Raddatz G, Seitz HK, Ho AD, Lyko F, Linhart HG.

Oncogene. 2015 Apr 2;34(14):1822-30. doi: 10.1038/onc.2014.114. Epub 2014 May 19.

PMID:
24837369
11.

[DNA methylation and cancer].

Yoshikawa H.

Gan To Kagaku Ryoho. 2007 Feb;34(2):145-9. Review. Japanese.

PMID:
17301518
12.

A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer.

Huidobro C, Urdinguio RG, Rodríguez RM, Mangas C, Calvanese V, Martínez-Camblor P, Ferrero C, Parra-Blanco A, Rodrigo L, Obaya AJ, Suárez-Fernández L, Astudillo A, Hernando H, Ballestar E, Fernández AF, Fraga MF.

Eur J Cancer. 2012 Sep;48(14):2270-81. doi: 10.1016/j.ejca.2011.12.019. Epub 2012 Jan 13.

PMID:
22244828
13.

Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development.

Hu YG, Hirasawa R, Hu JL, Hata K, Li CL, Jin Y, Chen T, Li E, Rigolet M, Viegas-Péquignot E, Sasaki H, Xu GL.

Hum Mol Genet. 2008 Sep 1;17(17):2654-64. doi: 10.1093/hmg/ddn165. Epub 2008 Jun 10.

PMID:
18544626
14.

The de novo methyltransferases DNMT3a and DNMT3b target the murine gammaherpesvirus immediate-early gene 50 promoter during establishment of latency.

Gray KS, Forrest JC, Speck SH.

J Virol. 2010 May;84(10):4946-59. doi: 10.1128/JVI.00060-10. Epub 2010 Mar 3.

15.

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells.

Robert MF, Morin S, Beaulieu N, Gauthier F, Chute IC, Barsalou A, MacLeod AR.

Nat Genet. 2003 Jan;33(1):61-5. Epub 2002 Dec 23.

PMID:
12496760
16.

Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation.

Weisenberger DJ, Velicescu M, Cheng JC, Gonzales FA, Liang G, Jones PA.

Mol Cancer Res. 2004 Jan;2(1):62-72.

17.

Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells.

Meilinger D, Fellinger K, Bultmann S, Rothbauer U, Bonapace IM, Klinkert WE, Spada F, Leonhardt H.

EMBO Rep. 2009 Nov;10(11):1259-64. doi: 10.1038/embor.2009.201. Epub 2009 Oct 2.

18.

Genetic and epigenetic variation in the DNMT3B and MTHFR genes and colorectal adenoma risk.

Ho V, Ashbury JE, Taylor S, Vanner S, King WD.

Environ Mol Mutagen. 2016 May;57(4):261-8. doi: 10.1002/em.22010. Epub 2016 Apr 8.

PMID:
27062459
19.

Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis.

Hlady RA, Novakova S, Opavska J, Klinkebiel D, Peters SL, Bies J, Hannah J, Iqbal J, Anderson KM, Siebler HM, Smith LM, Greiner TC, Bastola D, Joshi S, Lockridge O, Simpson MA, Felsher DW, Wagner KU, Chan WC, Christman JK, Opavsky R.

J Clin Invest. 2012 Jan;122(1):163-77. doi: 10.1172/JCI57292. Epub 2011 Dec 1.

20.

∆ DNMT3B4-del Contributes to Aberrant DNA Methylation Patterns in Lung Tumorigenesis.

Ma MZ, Lin R, Carrillo J, Bhutani M, Pathak A, Ren H, Li Y, Song J, Mao L.

EBioMedicine. 2015 Sep 7;2(10):1340-50. doi: 10.1016/j.ebiom.2015.09.002. eCollection 2015 Oct.

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