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Items: 1 to 20 of 104

1.

PI3Kβ plays a critical role in neutrophil activation by immune complexes.

Kulkarni S, Sitaru C, Jakus Z, Anderson KE, Damoulakis G, Davidson K, Hirose M, Juss J, Oxley D, Chessa TA, Ramadani F, Guillou H, Segonds-Pichon A, Fritsch A, Jarvis GE, Okkenhaug K, Ludwig R, Zillikens D, Mocsai A, Vanhaesebroeck B, Stephens LR, Hawkins PT.

Sci Signal. 2011 Apr 12;4(168):ra23. doi: 10.1126/scisignal.2001617.

2.

Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae.

Boyle KB, Gyori D, Sindrilaru A, Scharffetter-Kochanek K, Taylor PR, Mócsai A, Stephens LR, Hawkins PT.

J Immunol. 2011 Mar 1;186(5):2978-89. doi: 10.4049/jimmunol.1002268. Epub 2011 Jan 21.

3.

Neutrophil cell surface receptors and their intracellular signal transduction pathways.

Futosi K, Fodor S, Mócsai A.

Int Immunopharmacol. 2013 Nov;17(3):638-50. doi: 10.1016/j.intimp.2013.06.034. Epub 2013 Aug 30. Review.

4.

Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcγR signaling.

Sadik CD, Kim ND, Iwakura Y, Luster AD.

Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):E3177-85. doi: 10.1073/pnas.1213797109. Epub 2012 Oct 29.

5.

Phosphoinositide 3-kinases gamma and delta, linkers of coordinate C5a receptor-Fcgamma receptor activation and immune complex-induced inflammation.

Konrad S, Ali SR, Wiege K, Syed SN, Engling L, Piekorz RP, Hirsch E, Nürnberg B, Schmidt RE, Gessner JE.

J Biol Chem. 2008 Nov 28;283(48):33296-303. doi: 10.1074/jbc.M804617200. Epub 2008 Sep 11.

6.

Reprint of Neutrophil cell surface receptors and their intracellular signal transduction pathways.

Futosi K, Fodor S, Mócsai A.

Int Immunopharmacol. 2013 Dec;17(4):1185-97. doi: 10.1016/j.intimp.2013.11.010. Epub 2013 Nov 18. Review.

PMID:
24263067
7.
8.

PTPN22 Is a Critical Regulator of Fcγ Receptor-Mediated Neutrophil Activation.

Vermeren S, Miles K, Chu JY, Salter D, Zamoyska R, Gray M.

J Immunol. 2016 Dec 15;197(12):4771-4779. Epub 2016 Nov 2.

9.

Leukotriene B4 augments and restores Fc gammaRs-dependent phagocytosis in macrophages.

Okamoto F, Saeki K, Sumimoto H, Yamasaki S, Yokomizo T.

J Biol Chem. 2010 Dec 24;285(52):41113-21. doi: 10.1074/jbc.M110.175497. Epub 2010 Oct 19.

10.

Non-canonical PI3K-Cdc42-Pak-Mek-Erk Signaling Promotes Immune-Complex-Induced Apoptosis in Human Neutrophils.

Chu JY, Dransfield I, Rossi AG, Vermeren S.

Cell Rep. 2016 Oct 4;17(2):374-386. doi: 10.1016/j.celrep.2016.09.006.

11.

Immobilized immune complexes induce neutrophil extracellular trap release by human neutrophil granulocytes via FcγRIIIB and Mac-1.

Behnen M, Leschczyk C, Möller S, Batel T, Klinger M, Solbach W, Laskay T.

J Immunol. 2014 Aug 15;193(4):1954-65. doi: 10.4049/jimmunol.1400478. Epub 2014 Jul 14.

12.

A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis.

Kim ND, Chou RC, Seung E, Tager AM, Luster AD.

J Exp Med. 2006 Apr 17;203(4):829-35. Epub 2006 Mar 27.

13.

Functional regulation of human neutrophil Fc gamma receptors.

Selvaraj P, Fifadara N, Nagarajan S, Cimino A, Wang G.

Immunol Res. 2004;29(1-3):219-30. Review.

PMID:
15181284
14.

The regulatory subunits of PI3Kγ control distinct neutrophil responses.

Deladeriere A, Gambardella L, Pan D, Anderson KE, Hawkins PT, Stephens LR.

Sci Signal. 2015 Jan 20;8(360):ra8. doi: 10.1126/scisignal.2005564.

PMID:
25605974
15.

Syk-dependent signaling pathways in neutrophils and macrophages are indispensable in the pathogenesis of anti-collagen antibody-induced arthritis.

Ozaki N, Suzuki S, Ishida M, Harada Y, Tanaka K, Sato Y, Kono T, Kubo M, Kitamura D, Encinas J, Hara H, Yoshida H.

Int Immunol. 2012 Sep;24(9):539-50. doi: 10.1093/intimm/dxs078.

PMID:
22914861
16.

Human neutrophil Fcgamma receptors initiate and play specialized nonredundant roles in antibody-mediated inflammatory diseases.

Tsuboi N, Asano K, Lauterbach M, Mayadas TN.

Immunity. 2008 Jun;28(6):833-46. doi: 10.1016/j.immuni.2008.04.013.

17.

The immunoglobulin, IgG Fc receptor and complement triangle in autoimmune diseases.

Karsten CM, Köhl J.

Immunobiology. 2012 Nov;217(11):1067-79. doi: 10.1016/j.imbio.2012.07.015. Review.

PMID:
22964232
18.
19.

R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation.

Braselmann S, Taylor V, Zhao H, Wang S, Sylvain C, Baluom M, Qu K, Herlaar E, Lau A, Young C, Wong BR, Lovell S, Sun T, Park G, Argade A, Jurcevic S, Pine P, Singh R, Grossbard EB, Payan DG, Masuda ES.

J Pharmacol Exp Ther. 2006 Dec;319(3):998-1008. Epub 2006 Aug 31. Erratum in: J Pharmacol Exp Ther. 2013 May;345(2):326.

20.

Effects of the protein tyrosine phosphatase CD45 on FcgammaRIIa signaling and neutrophil function.

Gao H, Henderson A, Flynn DC, Landreth KS, Ericson SG.

Exp Hematol. 2000 Sep;28(9):1062-70.

PMID:
11008019

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