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Items: 1 to 20 of 83

1.

Crystal structure of the Leishmania major MIX protein: a scaffold protein that mediates protein-protein interactions.

Gorman MA, Uboldi AD, Walsh PJ, Tan KS, Hansen G, Huyton T, Ji H, Curtis J, Kedzierski L, Papenfuss AT, Dogovski C, Perugini MA, Simpson RJ, Handman E, Parker MW.

Protein Sci. 2011 Jun;20(6):1060-8. doi: 10.1002/pro.631.

2.

The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of Leishmania detoxification pathway.

Fiorillo A, Colotti G, Boffi A, Baiocco P, Ilari A.

PLoS Negl Trop Dis. 2012;6(8):e1781. doi: 10.1371/journal.pntd.0001781.

3.

Acylation-dependent and-independent membrane targeting and distinct functions of small myristoylated proteins (SMPs) in Leishmania major.

Tull D, Heng J, Gooley PR, Naderer T, McConville MJ.

Int J Parasitol. 2012;42(3):239-47. doi: 10.1016/j.ijpara.2011.12.004.

PMID:
22281304
4.

The Hus1 homologue of Leishmania major encodes a nuclear protein that participates in DNA damage response.

Nunes VS, Damasceno JD, Freire R, Tosi LR.

Mol Biochem Parasitol. 2011 May;177(1):65-9. doi: 10.1016/j.molbiopara.2011.01.011.

5.

A mitochondrial protein affects cell morphology, mitochondrial segregation and virulence in Leishmania.

Uboldi AD, Lueder FB, Walsh P, Spurck T, McFadden GI, Curtis J, Likic VA, Perugini MA, Barson M, Lithgow T, Handman E.

Int J Parasitol. 2006 Dec;36(14):1499-514.

PMID:
17011565
6.

The crystal structure of the Leishmania major deoxyuridine triphosphate nucleotidohydrolase in complex with nucleotide analogues, dUMP, and deoxyuridine.

Hemsworth GR, Moroz OV, Fogg MJ, Scott B, Bosch-Navarrete C, González-Pacanowska D, Wilson KS.

J Biol Chem. 2011 May 6;286(18):16470-81. doi: 10.1074/jbc.M111.224873.

7.

Cloning, expression and dynamic simulation of TRYP6 from Leishmania major (MRHO/IR/75/ER).

Eslami G, Frikha F, Salehi R, Khamesipour A, Hejazi H, Nilforoushzadeh MA.

Mol Biol Rep. 2011 Aug;38(6):3765-76. doi: 10.1007/s11033-010-0492-5.

PMID:
21120619
8.

Structural insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.

Sampathkumar P, Roach C, Michels PA, Hol WG.

J Mol Biol. 2008 Sep 12;381(4):867-80. doi: 10.1016/j.jmb.2008.05.089.

PMID:
18598704
9.

Type I signal peptidase from Leishmania is a target of the immune response in human cutaneous and visceral leishmaniasis.

Rafati S, Salmanian AH, Taheri T, Masina S, Schaff C, Taslimi Y, Fasel N.

Mol Biochem Parasitol. 2004 May;135(1):13-20.

PMID:
15287582
10.

Molecular cloning, biochemical and structural analysis of elongation factor-1 alpha from Leishmania donovani: comparison with the mammalian homologue.

Nandan D, Cherkasov A, Sabouti R, Yi T, Reiner NE.

Biochem Biophys Res Commun. 2003 Mar 21;302(4):646-52.

PMID:
12646217
11.

Structural characterization of the As/Sb reductase LmACR2 from Leishmania major.

Mukhopadhyay R, Bisacchi D, Zhou Y, Armirotti A, Bordo D.

J Mol Biol. 2009 Mar 13;386(5):1229-39. doi: 10.1016/j.jmb.2008.07.056.

PMID:
18687336
12.

Leishmania: overexpression and comparative structural analysis of the stage-regulated meta 1 gene.

Uliana SR, Goyal N, Freymüller E, Smith DF.

Exp Parasitol. 1999 Jul;92(3):183-91.

PMID:
10403759
13.

A genomic-based approach combining in vivo selection in mice to identify a novel virulence gene in Leishmania.

Zhang WW, Peacock CS, Matlashewski G.

PLoS Negl Trop Dis. 2008 Jun 11;2(6):e248. doi: 10.1371/journal.pntd.0000248.

14.
15.

Leishmania major CorA-like magnesium transporters play a critical role in parasite development and virulence.

Zhu Y, Davis A, Smith BJ, Curtis J, Handman E.

Int J Parasitol. 2009 May;39(6):713-23. doi: 10.1016/j.ijpara.2008.11.010.

PMID:
19136005
16.

Molecular modeling of a Leishmania antigen eIF-4A: identification of a potential epitope implicated in the adjuvant effect.

Hamza A, Kébaïer K, Vasilescu D, Sarma MH, Sarma RH.

J Biomol Struct Dyn. 2003 Aug;21(1):43-53. Erratum in: J Biomol Struct Dyn. 2003 Oct;21(2):following table of contents.

PMID:
12854958
17.

Biological network modeling identifies IPCS in Leishmania as a therapeutic target.

Mandlik V, Shinde S, Chaudhary A, Singh S.

Integr Biol (Camb). 2012 Sep;4(9):1130-42. doi: 10.1039/c2ib20037f.

PMID:
22842708
18.
19.

Functional characterization of stage-specific aminotransferases from trypanosomatids.

Marciano D, Maugeri DA, Cazzulo JJ, Nowicki C.

Mol Biochem Parasitol. 2009 Aug;166(2):172-82. doi: 10.1016/j.molbiopara.2009.04.001.

PMID:
19443056
20.

Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease.

Ljunggren A, Redzynia I, Alvarez-Fernandez M, Abrahamson M, Mort JS, Krupa JC, Jaskolski M, Bujacz G.

J Mol Biol. 2007 Aug 3;371(1):137-53.

PMID:
17561110
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