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Items: 1 to 20 of 176

1.

Proton-transport mechanisms in cytochrome c oxidase revealed by studies of kinetic isotope effects.

Johansson AL, Chakrabarty S, Berthold CL, Högbom M, Warshel A, Brzezinski P.

Biochim Biophys Acta. 2011 Sep;1807(9):1083-94. doi: 10.1016/j.bbabio.2011.03.012. Epub 2011 Apr 2.

2.

Intricate role of water in proton transport through cytochrome c oxidase.

Lee HJ, Svahn E, Swanson JM, Lepp H, Voth GA, Brzezinski P, Gennis RB.

J Am Chem Soc. 2010 Nov 17;132(45):16225-39. doi: 10.1021/ja107244g. Epub 2010 Oct 21.

3.

Variable proton-pumping stoichiometry in structural variants of cytochrome c oxidase.

Brzezinski P, Johansson AL.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):710-23. doi: 10.1016/j.bbabio.2010.02.020. Epub 2010 Feb 23. Review.

4.
5.

A pathogenic mutation in cytochrome c oxidase results in impaired proton pumping while retaining O(2)-reduction activity.

Namslauer I, Lee HJ, Gennis RB, Brzezinski P.

Biochim Biophys Acta. 2010 May;1797(5):550-6. doi: 10.1016/j.bbabio.2010.01.027. Epub 2010 Feb 1.

6.

Charge transfer in the K proton pathway linked to electron transfer to the catalytic site in cytochrome c oxidase.

Lepp H, Svahn E, Faxén K, Brzezinski P.

Biochemistry. 2008 Apr 29;47(17):4929-35. doi: 10.1021/bi7024707. Epub 2008 Apr 5.

PMID:
18393448
7.

Deuterium isotope effect of proton pumping in cytochrome c oxidase.

Salomonsson L, Brändén G, Brzezinski P.

Biochim Biophys Acta. 2008 Apr;1777(4):343-50. doi: 10.1016/j.bbabio.2007.09.009. Epub 2007 Oct 6.

8.

A mechanistic principle for proton pumping by cytochrome c oxidase.

Faxén K, Gilderson G, Adelroth P, Brzezinski P.

Nature. 2005 Sep 8;437(7056):286-9.

PMID:
16148937
9.

Structural elements involved in proton translocation by cytochrome c oxidase as revealed by backbone amide hydrogen-deuterium exchange of the E286H mutant.

Busenlehner LS, Brändén G, Namslauer I, Brzezinski P, Armstrong RN.

Biochemistry. 2008 Jan 8;47(1):73-83. Epub 2007 Dec 6.

PMID:
18052347
10.

Functional effects of mutations in cytochrome c oxidase related to prostate cancer.

Namslauer I, Dietz MS, Brzezinski P.

Biochim Biophys Acta. 2011 Oct;1807(10):1336-41. doi: 10.1016/j.bbabio.2011.02.005. Epub 2011 Feb 16.

11.
12.

The timing of proton migration in membrane-reconstituted cytochrome c oxidase.

Salomonsson L, Faxén K, Adelroth P, Brzezinski P.

Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17624-9. Epub 2005 Nov 23.

13.

Aspartate-132 in cytochrome c oxidase from Rhodobacter sphaeroides is involved in a two-step proton transfer during oxo-ferryl formation.

Smirnova IA, Adelroth P, Gennis RB, Brzezinski P.

Biochemistry. 1999 May 25;38(21):6826-33.

PMID:
10346904
14.

Plasticity of proton pathway structure and water coordination in cytochrome c oxidase.

Namslauer A, Lepp H, Brändén M, Jasaitis A, Verkhovsky MI, Brzezinski P.

J Biol Chem. 2007 May 18;282(20):15148-58. Epub 2007 Mar 15.

15.

Proton uptake and pKa changes in the uncoupled Asn139Cys variant of cytochrome c oxidase.

Johansson AL, Carlsson J, Högbom M, Hosler JP, Gennis RB, Brzezinski P.

Biochemistry. 2013 Feb 5;52(5):827-36. doi: 10.1021/bi301597a. Epub 2013 Jan 25.

PMID:
23305515
16.

On the role of the K-proton transfer pathway in cytochrome c oxidase.

Brändén M, Sigurdson H, Namslauer A, Gennis RB, Adelroth P, Brzezinski P.

Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5013-8. Epub 2001 Apr 10.

18.

Impaired proton pumping in cytochrome c oxidase upon structural alteration of the D pathway.

Lepp H, Salomonsson L, Zhu JP, Gennis RB, Brzezinski P.

Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):897-903. doi: 10.1016/j.bbabio.2008.04.013. Epub 2008 Apr 16.

19.
20.

Structural Changes and Proton Transfer in Cytochrome c Oxidase.

Vilhjálmsdóttir J, Johansson AL, Brzezinski P.

Sci Rep. 2015 Aug 27;5:12047. doi: 10.1038/srep12047.

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