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Practices, patients and (im)perfect data--feasibility of a randomised controlled clinical drug trial in German general practices.

Gágyor I, Bleidorn J, Wegscheider K, Hummers-Pradier E, Kochen MM.

Trials. 2011 Apr 1;12:91. doi: 10.1186/1745-6215-12-91.


Symptomatic treatment (ibuprofen) or antibiotics (ciprofloxacin) for uncomplicated urinary tract infection?--results of a randomized controlled pilot trial.

Bleidorn J, Gágyor I, Kochen MM, Wegscheider K, Hummers-Pradier E.

BMC Med. 2010 May 26;8:30. doi: 10.1186/1741-7015-8-30.


Immediate versus conditional treatment of uncomplicated urinary tract infection - a randomized-controlled comparative effectiveness study in general practices.

Gágyor I, Hummers-Pradier E, Kochen MM, Schmiemann G, Wegscheider K, Bleidorn J.

BMC Infect Dis. 2012 Jun 28;12:146. doi: 10.1186/1471-2334-12-146.


Uva-ursi extract and ibuprofen as alternative treatments of adult female urinary tract infection (ATAFUTI): study protocol for a randomised controlled trial.

Trill J, Simpson C, Webley F, Radford M, Stanton L, Maishman T, Galanopoulou A, Flower A, Eyles C, Willcox M, Hay A, Griffiths G, Little P, Lewith G, Moore M.

Trials. 2017 Sep 8;18(1):421. doi: 10.1186/s13063-017-2145-7.


Predicting antibiotic prescription after symptomatic treatment for urinary tract infection: development of a model using data from an RCT in general practice.

Gágyor I, Haasenritter J, Bleidorn J, McIsaac W, Schmiemann G, Hummers-Pradier E, Himmel W.

Br J Gen Pract. 2016 Apr;66(645):e234-40. doi: 10.3399/bjgp16X684361. Epub 2016 Mar 10.


Why do - or don't - patients with urinary tract infection participate in a clinical trial? A qualitative study in German family medicine.

Bleidorn J, Bucak S, Gágyor I, Hummers-Pradier E, Dierks ML.

Ger Med Sci. 2015 Oct 14;13:Doc17. doi: 10.3205/000221. eCollection 2015.


Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial.

Gágyor I, Bleidorn J, Kochen MM, Schmiemann G, Wegscheider K, Hummers-Pradier E.

BMJ. 2015 Dec 23;351:h6544. doi: 10.1136/bmj.h6544.


Ibuprofen versus pivmecillinam for uncomplicated urinary tract infection in women-A double-blind, randomized non-inferiority trial.

Vik I, Bollestad M, Grude N, Bærheim A, Damsgaard E, Neumark T, Bjerrum L, Cordoba G, Olsen IC, Lindbæk M.

PLoS Med. 2018 May 15;15(5):e1002569. doi: 10.1371/journal.pmed.1002569. eCollection 2018 May.


Time to symptom relief for uncomplicated urinary tract infection treated with extended-release ciprofloxacin: a prospective, open-label, uncontrolled primary care study.

Klimberg I, Shockey G, Ellison H, Fuller-Jonap F, Colgan R, Song J, Keating K, Cyrus P.

Curr Med Res Opin. 2005 Aug;21(8):1241-50.


Resistance profiles of urinary tract infections in general practice--an observational study.

Schmiemann G, Gágyor I, Hummers-Pradier E, Bleidorn J.

BMC Urol. 2012 Nov 21;12:33. doi: 10.1186/1471-2490-12-33.


A trial comparing low-dose, short-course ciprofloxacin and standard 7 day therapy with co-trimoxazole or nitrofurantoin in the treatment of uncomplicated urinary tract infection.

Iravani A, Klimberg I, Briefer C, Munera C, Kowalsky SF, Echols RM.

J Antimicrob Chemother. 1999 Mar;43 Suppl A:67-75.


SCISSOR-Spinal Cord Injury Study on Small molecule-derived Rho inhibition: a clinical study protocol.

Kopp MA, Liebscher T, Watzlawick R, Martus P, Laufer S, Blex C, Schindler R, Jungehulsing GJ, Knüppel S, Kreutzträger M, Ekkernkamp A, Dirnagl U, Strittmatter SM, Niedeggen A, Schwab JM.

BMJ Open. 2016 Jul 26;6(7):e010651. doi: 10.1136/bmjopen-2015-010651.


Reducing antibiotic use for uncomplicated urinary tract infection in general practice by treatment with uva-ursi (REGATTA) - a double-blind, randomized, controlled comparative effectiveness trial.

Afshar K, Fleischmann N, Schmiemann G, Bleidorn J, Hummers-Pradier E, Friede T, Wegscheider K, Moore M, Gágyor I.

BMC Complement Altern Med. 2018 Jul 3;18(1):203. doi: 10.1186/s12906-018-2266-x.


Recurrent urinary tract infections and complications after symptomatic versus antibiotic treatment: follow-up of a randomised controlled trial.

Bleidorn J, Hummers-Pradier E, Schmiemann G, Wiese B, Gágyor I.

Ger Med Sci. 2016 Feb 10;14:Doc01. doi: 10.3205/000228. eCollection 2016.


Feasibility, acceptability and effectiveness of an online alternative to face-to-face consultation in general practice: a mixed-methods study of webGP in six Devon practices.

Carter M, Fletcher E, Sansom A, Warren FC, Campbell JL.

BMJ Open. 2018 Feb 15;8(2):e018688. doi: 10.1136/bmjopen-2017-018688.


Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting: randomised, double blind trial.

Kronenberg A, Bütikofer L, Odutayo A, Mühlemann K, da Costa BR, Battaglia M, Meli DN, Frey P, Limacher A, Reichenbach S, Jüni P.

BMJ. 2017 Nov 7;359:j4784. doi: 10.1136/bmj.j4784. Erratum in: BMJ. 2017 Nov 13;359:j5268.


A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.

Southworth S, Peters J, Rock A, Pavliv L.

Clin Ther. 2009 Sep;31(9):1922-35. doi: 10.1016/j.clinthera.2009.08.026.


Maximising recruitment and retention of general practices in clinical trials: a case study.

Dormandy E, Kavalier F, Logan J, Harris H, Ishmael N, Marteau TM; SHIFT research team.

Br J Gen Pract. 2008 Nov;58(556):759-66, i-ii. doi: 10.3399/bjgp08X319666.


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