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Items: 1 to 20 of 119

1.

Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals.

Johnson AD, Newton-Cheh C, Chasman DI, Ehret GB, Johnson T, Rose L, Rice K, Verwoert GC, Launer LJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, Caulfield M, van Duijn CM, Ridker PM, Munroe PB, Levy D; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium; Global BPgen Consortium; Women's Genome Health Study.

Hypertension. 2011 May;57(5):903-10. doi: 10.1161/HYPERTENSIONAHA.110.158667. Epub 2011 Mar 28.

2.

Pharmacogenetics of antihypertensive drug responses.

Schwartz GL, Turner ST.

Am J Pharmacogenomics. 2004;4(3):151-60. Review.

PMID:
15174896
3.

The C-532T polymorphism of the angiotensinogen gene is associated with pulse pressure: a possible explanation for heterogeneity in genetic association studies of AGT and hypertension.

Baker M, Rahman T, Hall D, Avery PJ, Mayosi BM, Connell JM, Farrall M, Watkins H, Keavney B.

Int J Epidemiol. 2007 Dec;36(6):1356-62. Epub 2007 Nov 12.

PMID:
17998241
4.

Hypertension susceptibility loci and blood pressure response to antihypertensives: results from the pharmacogenomic evaluation of antihypertensive responses study.

Gong Y, McDonough CW, Wang Z, Hou W, Cooper-DeHoff RM, Langaee TY, Beitelshees AL, Chapman AB, Gums JG, Bailey KR, Boerwinkle E, Turner ST, Johnson JA.

Circ Cardiovasc Genet. 2012 Dec;5(6):686-91. doi: 10.1161/CIRCGENETICS.112.964080. Epub 2012 Oct 19.

5.

Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response.

Shahin MH, Sá AC, Webb A, Gong Y, Langaee T, McDonough CW, Riva A, Beitleshees AL, Chapman AB, Gums JG, Turner ST, Boerwinkle E, Scherer SE, Sadee W, Cooper-DeHoff RM, Johnson JA.

Circ Cardiovasc Genet. 2017 Jan;10(1). pii: e001404. doi: 10.1161/CIRCGENETICS.116.001404.

6.

Reevaluation of the association of seven candidate genes with blood pressure and hypertension: a replication study and meta-analysis with a larger sample size.

Takeuchi F, Yamamoto K, Katsuya T, Sugiyama T, Nabika T, Ohnaka K, Yamaguchi S, Takayanagi R, Ogihara T, Kato N.

Hypertens Res. 2012 Aug;35(8):825-31. doi: 10.1038/hr.2012.43. Epub 2012 Mar 29.

PMID:
22456346
7.

Polymorphisms of the beta1-adrenergic receptor gene are associated with essential hypertension in Chinese.

Peng Y, Xue H, Luo L, Yao W, Li R.

Clin Chem Lab Med. 2009;47(10):1227-31. doi: 10.1515/CCLM.2009.276.

PMID:
19743955
8.

Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide.

Turner ST, Boerwinkle E, O'Connell JR, Bailey KR, Gong Y, Chapman AB, McDonough CW, Beitelshees AL, Schwartz GL, Gums JG, Padmanabhan S, Hiltunen TP, Citterio L, Donner KM, Hedner T, Lanzani C, Melander O, Saarela J, Ripatti S, Wahlstrand B, Manunta P, Kontula K, Dominiczak AF, Cooper-DeHoff RM, Johnson JA.

Hypertension. 2013 Aug;62(2):391-7. doi: 10.1161/HYPERTENSIONAHA.111.00436. Epub 2013 Jun 10.

9.

Association of common polymorphisms in β1-adrenergic receptor with antihypertensive response to carvedilol.

Si D, Wang J, Xu Y, Chen X, Zhang M, Zhou H.

J Cardiovasc Pharmacol. 2014 Oct;64(4):306-9. doi: 10.1097/FJC.0000000000000119.

PMID:
25291495
10.

Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials.

Magvanjav O, Gong Y, McDonough CW, Chapman AB, Turner ST, Gums JG, Bailey KR, Boerwinkle E, Beitelshees AL, Tanaka T, Kubo M, Pepine CJ, Cooper-DeHoff RM, Johnson JA.

J Am Heart Assoc. 2017 Nov 2;6(11). pii: e006522. doi: 10.1161/JAHA.117.006522.

11.

G protein receptor kinase 4 polymorphisms: β-blocker pharmacogenetics and treatment-related outcomes in hypertension.

Vandell AG, Lobmeyer MT, Gawronski BE, Langaee TY, Gong Y, Gums JG, Beitelshees AL, Turner ST, Chapman AB, Cooper-DeHoff RM, Bailey KR, Boerwinkle E, Pepine CJ, Liggett SB, Johnson JA.

Hypertension. 2012 Oct;60(4):957-64. doi: 10.1161/HYPERTENSIONAHA.112.198721. Epub 2012 Sep 4.

12.

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.

Vimaleswaran KS, Cavadino A, Berry DJ; LifeLines Cohort Study investigators, Jorde R, Dieffenbach AK, Lu C, Alves AC, Heerspink HJ, Tikkanen E, Eriksson J, Wong A, Mangino M, Jablonski KA, Nolte IM, Houston DK, Ahluwalia TS, van der Most PJ, Pasko D, Zgaga L, Thiering E, Vitart V, Fraser RM, Huffman JE, de Boer RA, Schöttker B, Saum KU, McCarthy MI, Dupuis J, Herzig KH, Sebert S, Pouta A, Laitinen J, Kleber ME, Navis G, Lorentzon M, Jameson K, Arden N, Cooper JA, Acharya J, Hardy R, Raitakari O, Ripatti S, Billings LK, Lahti J, Osmond C, Penninx BW, Rejnmark L, Lohman KK, Paternoster L, Stolk RP, Hernandez DG, Byberg L, Hagström E, Melhus H, Ingelsson E, Mellström D, Ljunggren O, Tzoulaki I, McLachlan S, Theodoratou E, Tiesler CM, Jula A, Navarro P, Wright AF, Polasek O; International Consortium for Blood Pressure (ICBP); Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium; Global Blood Pressure Genetics (Global BPGen) consortium; Caroline Hayward, Wilson JF, Rudan I, Salomaa V, Heinrich J, Campbell H, Price JF, Karlsson M, Lind L, Michaëlsson K, Bandinelli S, Frayling TM, Hartman CA, Sørensen TI, Kritchevsky SB, Langdahl BL, Eriksson JG, Florez JC, Spector TD, Lehtimäki T, Kuh D, Humphries SE, Cooper C, Ohlsson C, März W, de Borst MH, Kumari M, Kivimaki M, Wang TJ, Power C, Brenner H, Grimnes G, van der Harst P, Snieder H, Hingorani AD, Pilz S, Whittaker JC, Järvelin MR, Hyppönen E.

Lancet Diabetes Endocrinol. 2014 Sep;2(9):719-29. doi: 10.1016/S2213-8587(14)70113-5. Epub 2014 Jun 25.

13.

Studies of associations between the Arg389Gly polymorphism of the beta1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects.

Gjesing AP, Andersen G, Albrechtsen A, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabet Med. 2007 Apr;24(4):392-7. Epub 2007 Feb 28.

PMID:
17335470
14.

Common genetic variation of beta1- and beta2-adrenergic receptor and response to four classes of antihypertensive treatment.

Suonsyrjä T, Donner K, Hannila-Handelberg T, Fodstad H, Kontula K, Hiltunen TP.

Pharmacogenet Genomics. 2010 May;20(5):342-5. doi: 10.1097/FPC.0b013e328338e1b8.

PMID:
20300048
15.

Prediction of patient responses to antihypertensive drugs using genetic polymorphisms: investigation of renin-angiotensin system genes.

Dudley C, Keavney B, Casadei B, Conway J, Bird R, Ratcliffe P.

J Hypertens. 1996 Feb;14(2):259-62.

PMID:
8728305
16.

Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension.

Lynch AI, Boerwinkle E, Davis BR, Ford CE, Eckfeldt JH, Leiendecker-Foster C, Arnett DK.

JAMA. 2008 Jan 23;299(3):296-307. doi: 10.1001/jama.299.3.296. Erratum in: JAMA. 2009 Sep 9;302(10):1057-8.

PMID:
18212314
17.

Association of CYP2D6 and ADRB1 genes with hypotensive and antichronotropic action of betaxolol in patients with arterial hypertension.

Zateyshchikov DA, Minushkina LO, Brovkin AN, Savel'eva EG, Zateyshchikova AA, Manchaeva BB, Nikitin AG, Sidorenko BA, Nosikov VV.

Fundam Clin Pharmacol. 2007 Aug;21(4):437-43.

PMID:
17635183
18.

Associations between ADRB1 and CYP2D6 gene polymorphisms and the response to β-blocker therapy in hypertension.

Wu D, Li G, Deng M, Song W, Huang X, Guo X, Wu Z, Wu S, Xu J.

J Int Med Res. 2015 Jun;43(3):424-34. doi: 10.1177/0300060514563151. Epub 2015 Mar 30.

PMID:
25823457
19.

Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.

Bis JC, Sitlani C, Irvin R, Avery CL, Smith AV, Sun F, Evans DS, Musani SK, Li X, Trompet S, Krijthe BP, Harris TB, Quibrera PM, Brody JA, Demissie S, Davis BR, Wiggins KL, Tranah GJ, Lange LA, Sotoodehnia N, Stott DJ, Franco OH, Launer LJ, Stürmer T, Taylor KD, Cupples LA, Eckfeldt JH, Smith NL, Liu Y, Wilson JG, Heckbert SR, Buckley BM, Ikram MA, Boerwinkle E, Chen YD, de Craen AJ, Uitterlinden AG, Rotter JI, Ford I, Hofman A, Sattar N, Slagboom PE, Westendorp RG, Gudnason V, Vasan RS, Lumley T, Cummings SR, Taylor HA Jr, Post W, Jukema JW, Stricker BH, Whitsel EA, Psaty BM, Arnett D.

PLoS One. 2015 Oct 30;10(10):e0140496. doi: 10.1371/journal.pone.0140496. eCollection 2015.

20.

Carvedilol pharmacokinetics and pharmacodynamics in relation to CYP2D6 and ADRB pharmacogenetics.

Sehrt D, Meineke I, Tzvetkov M, Gültepe S, Brockmöller J.

Pharmacogenomics. 2011 Jun;12(6):783-95. doi: 10.2217/pgs.11.20. Epub 2011 May 23.

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