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Mutual regulation between the spindle checkpoint and APC/C.

Kim S, Yu H.

Semin Cell Dev Biol. 2011 Aug;22(6):551-8. doi: 10.1016/j.semcdb.2011.03.008. Epub 2011 Mar 23. Review.


Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20.

Morrow CJ, Tighe A, Johnson VL, Scott MI, Ditchfield C, Taylor SS.

J Cell Sci. 2005 Aug 15;118(Pt 16):3639-52. Epub 2005 Jul 26.


Cyclin A and Nek2A: APC/C-Cdc20 substrates invisible to the mitotic spindle checkpoint.

van Zon W, Wolthuis RM.

Biochem Soc Trans. 2010 Feb;38(Pt 1):72-7. doi: 10.1042/BST0380072. Review.


Roles of different pools of the mitotic checkpoint complex and the mechanisms of their disassembly.

Eytan E, Sitry-Shevah D, Teichner A, Hershko A.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10568-73. doi: 10.1073/pnas.1308928110. Epub 2013 Jun 10.


APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.

Mansfeld J, Collin P, Collins MO, Choudhary JS, Pines J.

Nat Cell Biol. 2011 Sep 18;13(10):1234-43. doi: 10.1038/ncb2347.


Expression of constitutively active CDK1 stabilizes APC-Cdh1 substrates and potentiates premature spindle assembly and checkpoint function in G1 cells.

Ma Y, Yuan X, Wyatt WR, Pomerening JR.

PLoS One. 2012;7(3):e33835. doi: 10.1371/journal.pone.0033835. Epub 2012 Mar 29.


Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation.

Reddy SK, Rape M, Margansky WA, Kirschner MW.

Nature. 2007 Apr 19;446(7138):921-5.


Correction of microtubule-kinetochore attachment errors: mechanisms and role in tumor suppression.

Ricke RM, van Deursen JM.

Semin Cell Dev Biol. 2011 Aug;22(6):559-65. doi: 10.1016/j.semcdb.2011.03.007. Epub 2011 Mar 23. Review.


Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation.

Izawa D, Pines J.

J Cell Biol. 2012 Oct 1;199(1):27-37. doi: 10.1083/jcb.201205170. Epub 2012 Sep 24.


Role of phosphorylation of Cdc20 in p31(comet)-stimulated disassembly of the mitotic checkpoint complex.

Miniowitz-Shemtov S, Eytan E, Ganoth D, Sitry-Shevah D, Dumin E, Hershko A.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8056-60. doi: 10.1073/pnas.1204081109. Epub 2012 May 7.


Regulation of APC-Cdc20 by the spindle checkpoint.

Yu H.

Curr Opin Cell Biol. 2002 Dec;14(6):706-14. Review.


Intermediates in the assembly of mitotic checkpoint complexes and their role in the regulation of the anaphase-promoting complex.

Kaisari S, Sitry-Shevah D, Miniowitz-Shemtov S, Hershko A.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):966-71. doi: 10.1073/pnas.1524551113. Epub 2016 Jan 11.


APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex.

Uzunova K, Dye BT, Schutz H, Ladurner R, Petzold G, Toyoda Y, Jarvis MA, Brown NG, Poser I, Novatchkova M, Mechtler K, Hyman AA, Stark H, Schulman BA, Peters JM.

Nat Struct Mol Biol. 2012 Nov;19(11):1116-23. doi: 10.1038/nsmb.2412. Epub 2012 Sep 24.


Molecular basis of APC/C regulation by the spindle assembly checkpoint.

Alfieri C, Chang L, Zhang Z, Yang J, Maslen S, Skehel M, Barford D.

Nature. 2016 Aug 25;536(7617):431-436. doi: 10.1038/nature19083. Epub 2016 Aug 10.


The spindle checkpoint: how do cells delay anaphase onset?

Sczaniecka MM, Hardwick KG.

SEB Exp Biol Ser. 2008;59:243-56. Review.


The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.

Nilsson J, Yekezare M, Minshull J, Pines J.

Nat Cell Biol. 2008 Dec;10(12):1411-20. doi: 10.1038/ncb1799. Epub 2008 Nov 9.


Functional interaction between BubR1 and securin in an anaphase-promoting complex/cyclosomeCdc20-independent manner.

Kim HS, Jeon YK, Ha GH, Park HY, Kim YJ, Shin HJ, Lee CG, Chung DH, Lee CW.

Cancer Res. 2009 Jan 1;69(1):27-36. doi: 10.1158/0008-5472.CAN-08-0820.


APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation.

Ge S, Skaar JR, Pagano M.

Cell Cycle. 2009 Jan 1;8(1):167-71. Epub 2009 Jan 11.


The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C).

Sczaniecka M, Feoktistova A, May KM, Chen JS, Blyth J, Gould KL, Hardwick KG.

J Biol Chem. 2008 Aug 22;283(34):23039-47. doi: 10.1074/jbc.M803594200. Epub 2008 Jun 13.


Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes.

Gui L, Homer H.

Development. 2012 Jun;139(11):1941-6. doi: 10.1242/dev.078352. Epub 2012 Apr 18.

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