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Items: 1 to 20 of 181

1.

Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing.

Leung DC, Dong KB, Maksakova IA, Goyal P, Appanah R, Lee S, Tachibana M, Shinkai Y, Lehnertz B, Mager DL, Rossi F, Lorincz MC.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5718-23. doi: 10.1073/pnas.1014660108. Epub 2011 Mar 22.

2.

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.

Matsui T, Leung D, Miyashita H, Maksakova IA, Miyachi H, Kimura H, Tachibana M, Lorincz MC, Shinkai Y.

Nature. 2010 Apr 8;464(7290):927-31. doi: 10.1038/nature08858. Epub 2010 Feb 17. Erratum in: Nature. 2014 Sep 4;513(7516):128.

PMID:
20164836
3.

Distinct roles of KAP1, HP1 and G9a/GLP in silencing of the two-cell-specific retrotransposon MERVL in mouse ES cells.

Maksakova IA, Thompson PJ, Goyal P, Jones SJ, Singh PB, Karimi MM, Lorincz MC.

Epigenetics Chromatin. 2013 Jun 4;6(1):15. doi: 10.1186/1756-8935-6-15.

4.

hnRNP K coordinates transcriptional silencing by SETDB1 in embryonic stem cells.

Thompson PJ, Dulberg V, Moon KM, Foster LJ, Chen C, Karimi MM, Lorincz MC.

PLoS Genet. 2015 Jan 22;11(1):e1004933. doi: 10.1371/journal.pgen.1004933. eCollection 2015 Jan. Erratum in: PLoS Genet. 2016 Oct 14;12 (10 ):e1006390.

5.

DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements, and chimeric transcripts in mESCs.

Karimi MM, Goyal P, Maksakova IA, Bilenky M, Leung D, Tang JX, Shinkai Y, Mager DL, Jones S, Hirst M, Lorincz MC.

Cell Stem Cell. 2011 Jun 3;8(6):676-87. doi: 10.1016/j.stem.2011.04.004.

6.

Ectopic DNMT3L triggers assembly of a repressive complex for retroviral silencing in somatic cells.

Kao TH, Liao HF, Wolf D, Tai KY, Chuang CY, Lee HS, Kuo HC, Hata K, Zhang X, Cheng X, Goff SP, Ooi SK, Bestor TH, Lin SP.

J Virol. 2014 Sep;88(18):10680-95. doi: 10.1128/JVI.01176-14. Epub 2014 Jul 2.

7.

Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells.

Liu S, Brind'Amour J, Karimi MM, Shirane K, Bogutz A, Lefebvre L, Sasaki H, Shinkai Y, Lorincz MC.

Genes Dev. 2014 Sep 15;28(18):2041-55. doi: 10.1101/gad.244848.114. Erratum in: Genes Dev. 2015 Jan 1;29(1):108.

8.

Regulation of DNA methylation turnover at LTR retrotransposons and imprinted loci by the histone methyltransferase Setdb1.

Leung D, Du T, Wagner U, Xie W, Lee AY, Goyal P, Li Y, Szulwach KE, Jin P, Lorincz MC, Ren B.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6690-5. doi: 10.1073/pnas.1322273111. Epub 2014 Apr 22.

9.

DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity.

Dong KB, Maksakova IA, Mohn F, Leung D, Appanah R, Lee S, Yang HW, Lam LL, Mager DL, Schübeler D, Tachibana M, Shinkai Y, Lorincz MC.

EMBO J. 2008 Oct 22;27(20):2691-701. doi: 10.1038/emboj.2008.193. Epub 2008 Sep 25.

10.

De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET.

Rowe HM, Friedli M, Offner S, Verp S, Mesnard D, Marquis J, Aktas T, Trono D.

Development. 2013 Feb 1;140(3):519-29. doi: 10.1242/dev.087585.

11.
12.

The histone methyltransferase SETDB1 represses endogenous and exogenous retroviruses in B lymphocytes.

Collins PL, Kyle KE, Egawa T, Shinkai Y, Oltz EM.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8367-72. doi: 10.1073/pnas.1422187112. Epub 2015 Jun 22.

13.

Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts.

Han P, Li W, Yang J, Shang C, Lin CH, Cheng W, Hang CT, Cheng HL, Chen CH, Wong J, Xiong Y, Zhao M, Drakos SG, Ghetti A, Li DY, Bernstein D, Chen HS, Quertermous T, Chang CP.

Biochim Biophys Acta. 2016 Jul;1863(7 Pt B):1772-81. doi: 10.1016/j.bbamcr.2016.03.002. Epub 2016 Mar 4.

PMID:
26952936
14.

G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription.

Tachibana M, Matsumura Y, Fukuda M, Kimura H, Shinkai Y.

EMBO J. 2008 Oct 22;27(20):2681-90. doi: 10.1038/emboj.2008.192. Epub 2008 Sep 25.

15.

Ethanol induced acetylation of histone at G9a exon1 and G9a-mediated histone H3 dimethylation leads to neurodegeneration in neonatal mice.

Subbanna S, Nagre NN, Shivakumar M, Umapathy NS, Psychoyos D, Basavarajappa BS.

Neuroscience. 2014 Jan 31;258:422-32. doi: 10.1016/j.neuroscience.2013.11.043. Epub 2013 Dec 1.

16.

Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A.

Chaturvedi CP, Somasundaram B, Singh K, Carpenedo RL, Stanford WL, Dilworth FJ, Brand M.

Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18845-50. doi: 10.1073/pnas.1213951109. Epub 2012 Oct 29.

17.

Role of distinct surfaces of the G9a ankyrin repeat domain in histone and DNA methylation during embryonic stem cell self-renewal and differentiation.

Bittencourt D, Lee BH, Gao L, Gerke DS, Stallcup MR.

Epigenetics Chromatin. 2014 Oct 22;7:27. doi: 10.1186/1756-8935-7-27. eCollection 2014.

18.

G9a/GLP histone lysine dimethyltransferase complex activity in the hippocampus and the entorhinal cortex is required for gene activation and silencing during memory consolidation.

Gupta-Agarwal S, Franklin AV, Deramus T, Wheelock M, Davis RL, McMahon LL, Lubin FD.

J Neurosci. 2012 Apr 18;32(16):5440-53. doi: 10.1523/JNEUROSCI.0147-12.2012.

19.

H3K9 methyltransferase G9a and the related molecule GLP.

Shinkai Y, Tachibana M.

Genes Dev. 2011 Apr 15;25(8):781-8. doi: 10.1101/gad.2027411. Review.

20.

MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.

Chang Y, Sun L, Kokura K, Horton JR, Fukuda M, Espejo A, Izumi V, Koomen JM, Bedford MT, Zhang X, Shinkai Y, Fang J, Cheng X.

Nat Commun. 2011 Nov 15;2:533. doi: 10.1038/ncomms1549.

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