Similar articles for PMID: 21426483

Year	Number of Results
1996	1
1997	1
2000	3
2001	1
2002	5
2003	3
2004	7
2005	2
2006	7
2007	10
2008	5
2009	8
2010	8
2011	11
2012	10
2013	6
2014	4
2015	3
2016	6
2017	5
2018	2
2019	1
2020	1
2021	2
2022	5
2023	1
2024	0

1

The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence.

Bernardes de Jesus B, Schneeberger K, Vera E, Tejera A, Harley CB, Blasco MA. Bernardes de Jesus B, et al. Aging Cell. 2011 Aug;10(4):604-21. doi: 10.1111/j.1474-9726.2011.00700.x. Epub 2011 Apr 14. Aging Cell. 2011. PMID: 21426483 Free PMC article.

2

Dysfunctional telomeres promote genomic instability and metastasis in the absence of telomerase activity in oncogene induced mammary cancer.

Bojovic B, Crowe DL. Bojovic B, et al. Mol Carcinog. 2013 Feb;52(2):103-17. doi: 10.1002/mc.21834. Epub 2011 Nov 15. Mol Carcinog. 2013. PMID: 22086874

3

The mTOR pathway is necessary for survival of mice with short telomeres.

Ferrara-Romeo I, Martinez P, Saraswati S, Whittemore K, Graña-Castro O, Thelma Poluha L, Serrano R, Hernandez-Encinas E, Blanco-Aparicio C, Maria Flores J, Blasco MA. Ferrara-Romeo I, et al. Nat Commun. 2020 Mar 3;11(1):1168. doi: 10.1038/s41467-020-14962-1. Nat Commun. 2020. PMID: 32127537 Free PMC article.

4

HMGB1 gene knockout in mouse embryonic fibroblasts results in reduced telomerase activity and telomere dysfunction.

Polanská E, Dobšáková Z, Dvořáčková M, Fajkus J, Štros M. Polanská E, et al. Chromosoma. 2012 Aug;121(4):419-31. doi: 10.1007/s00412-012-0373-x. Epub 2012 Apr 28. Chromosoma. 2012. PMID: 22544226

5

Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice.

Lee J, Reddy R, Barsky L, Scholes J, Chen H, Shi W, Driscoll B. Lee J, et al. Am J Physiol Lung Cell Mol Physiol. 2009 Jan;296(1):L57-70. doi: 10.1152/ajplung.90411.2008. Epub 2008 Oct 24. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 18952756 Free PMC article.

6

Functional interaction between DNA-PKcs and telomerase in telomere length maintenance.

Espejel S, Franco S, Sgura A, Gae D, Bailey SM, Taccioli GE, Blasco MA. Espejel S, et al. EMBO J. 2002 Nov 15;21(22):6275-87. doi: 10.1093/emboj/cdf593. EMBO J. 2002. PMID: 12426399 Free PMC article.

7

Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase.

Strong MA, Vidal-Cardenas SL, Karim B, Yu H, Guo N, Greider CW. Strong MA, et al. Mol Cell Biol. 2011 Jun;31(12):2369-79. doi: 10.1128/MCB.05312-11. Epub 2011 Apr 4. Mol Cell Biol. 2011. PMID: 21464209 Free PMC article.

8

The effect of TERC haploinsufficiency on the inheritance of telomere length.

Goldman F, Bouarich R, Kulkarni S, Freeman S, Du HY, Harrington L, Mason PJ, Londoño-Vallejo A, Bessler M. Goldman F, et al. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17119-24. doi: 10.1073/pnas.0505318102. Epub 2005 Nov 11. Proc Natl Acad Sci U S A. 2005. PMID: 16284252 Free PMC article.

9

Short telomeres initiate telomere recombination in primary and tumor cells.

Morrish TA, Greider CW. Morrish TA, et al. PLoS Genet. 2009 Jan;5(1):e1000357. doi: 10.1371/journal.pgen.1000357. Epub 2009 Jan 30. PLoS Genet. 2009. PMID: 19180191 Free PMC article.

10

Ectopic expression of human telomerase RNA component results in increased telomerase activity and elongated telomeres in bovine blastocysts.

Garrels W, Kues WB, Herrmann D, Holler S, Baulain U, Niemann H. Garrels W, et al. Biol Reprod. 2012 Oct 25;87(4):95. doi: 10.1095/biolreprod.112.100198. Print 2012 Oct. Biol Reprod. 2012. PMID: 22855562

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