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Items: 1 to 20 of 176

1.

An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition.

Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S, Morris M, Wyatt L, Farshid G, Lim YY, Lindeman GJ, Shannon MF, Drew PA, Khew-Goodall Y, Goodall GJ.

Mol Biol Cell. 2011 May 15;22(10):1686-98. doi: 10.1091/mbc.E11-02-0103. Epub 2011 Mar 16.

2.

Mesenchymal stem cells play a potential role in regulating the establishment and maintenance of epithelial-mesenchymal transition in MCF7 human breast cancer cells by paracrine and induced autocrine TGF-β.

Xu Q, Wang L, Li H, Han Q, Li J, Qu X, Huang S, Zhao RC.

Int J Oncol. 2012 Sep;41(3):959-68. doi: 10.3892/ijo.2012.1541. Epub 2012 Jul 3.

PMID:
22766682
3.

A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition.

Moes M, Le Béchec A, Crespo I, Laurini C, Halavatyi A, Vetter G, Del Sol A, Friederich E.

PLoS One. 2012;7(4):e35440. doi: 10.1371/journal.pone.0035440. Epub 2012 Apr 13.

4.

Autocrine TGF-β/ZEB/microRNA-200 signal transduction drives epithelial-mesenchymal transition: Kinetic models predict minimal drug dose to inhibit metastasis.

Rateitschak K, Kaderali L, Wolkenhauer O, Jaster R.

Cell Signal. 2016 Aug;28(8):861-70. doi: 10.1016/j.cellsig.2016.03.002. Epub 2016 Mar 19.

PMID:
27000495
5.

ZEB/miR-200 feedback loop: at the crossroads of signal transduction in cancer.

Hill L, Browne G, Tulchinsky E.

Int J Cancer. 2013 Feb 15;132(4):745-54. doi: 10.1002/ijc.27708. Epub 2012 Jul 21. Review.

6.

Specificity protein 1 (Sp1) maintains basal epithelial expression of the miR-200 family: implications for epithelial-mesenchymal transition.

Kolesnikoff N, Attema JL, Roslan S, Bert AG, Schwarz QP, Gregory PA, Goodall GJ.

J Biol Chem. 2014 Apr 18;289(16):11194-205. doi: 10.1074/jbc.M113.529172. Epub 2014 Mar 13.

7.

MiR-200c suppresses TGF-β signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF217 and ZEB1 in breast cancer.

Bai WD, Ye XM, Zhang MY, Zhu HY, Xi WJ, Huang X, Zhao J, Gu B, Zheng GX, Yang AG, Jia LT.

Int J Cancer. 2014 Sep 15;135(6):1356-68. doi: 10.1002/ijc.28782. Epub 2014 Mar 3.

8.

A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.

Ohashi S, Natsuizaka M, Naganuma S, Kagawa S, Kimura S, Itoh H, Kalman RA, Nakagawa M, Darling DS, Basu D, Gimotty PA, Klein-Szanto AJ, Diehl JA, Herlyn M, Nakagawa H.

Cancer Res. 2011 Nov 1;71(21):6836-47. doi: 10.1158/0008-5472.CAN-11-0846. Epub 2011 Sep 2.

9.

Pien Tze Huang inhibits metastasis of human colorectal carcinoma cells via modulation of TGF-β1/ZEB/miR-200 signaling network.

Shen A, Lin W, Chen Y, Liu L, Chen H, Zhuang Q, Lin J, Sferra TJ, Peng J.

Int J Oncol. 2015 Feb;46(2):685-90. doi: 10.3892/ijo.2014.2772. Epub 2014 Nov 24.

PMID:
25422078
10.

The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?

Brabletz S, Brabletz T.

EMBO Rep. 2010 Sep;11(9):670-7. doi: 10.1038/embor.2010.117. Epub 2010 Aug 13. Review.

11.

TGF-β-induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops.

Zhang J, Tian XJ, Zhang H, Teng Y, Li R, Bai F, Elankumaran S, Xing J.

Sci Signal. 2014 Sep 30;7(345):ra91. doi: 10.1126/scisignal.2005304.

PMID:
25270257
12.

Notch3 is important for TGF-β-induced epithelial-mesenchymal transition in non-small cell lung cancer bone metastasis by regulating ZEB-1.

Liu L, Chen X, Wang Y, Qu Z, Lu Q, Zhao J, Yan X, Zhang H, Zhou Y.

Cancer Gene Ther. 2014 Sep;21(9):364-72. doi: 10.1038/cgt.2014.39. Epub 2014 Aug 1.

PMID:
25080992
13.

Phosphoglucose isomerase/autocrine motility factor mediates epithelial-mesenchymal transition regulated by miR-200 in breast cancer cells.

Ahmad A, Aboukameel A, Kong D, Wang Z, Sethi S, Chen W, Sarkar FH, Raz A.

Cancer Res. 2011 May 1;71(9):3400-9. doi: 10.1158/0008-5472.CAN-10-0965. Epub 2011 Mar 9.

14.

Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors.

Ohashi S, Natsuizaka M, Wong GS, Michaylira CZ, Grugan KD, Stairs DB, Kalabis J, Vega ME, Kalman RA, Nakagawa M, Klein-Szanto AJ, Herlyn M, Diehl JA, Rustgi AK, Nakagawa H.

Cancer Res. 2010 May 15;70(10):4174-84. doi: 10.1158/0008-5472.CAN-09-4614. Epub 2010 Apr 27.

15.

EED regulates epithelial-mesenchymal transition of cancer cells induced by TGF-β.

Oktyabri D, Tange S, Terashima M, Ishimura A, Suzuki T.

Biochem Biophys Res Commun. 2014 Oct 10;453(1):124-30. doi: 10.1016/j.bbrc.2014.09.082. Epub 2014 Sep 26.

PMID:
25264103
16.

MicroRNA-200b regulates cell proliferation, invasion, and migration by directly targeting ZEB2 in gastric carcinoma.

Kurashige J, Kamohara H, Watanabe M, Hiyoshi Y, Iwatsuki M, Tanaka Y, Kinoshita K, Saito S, Baba Y, Baba H.

Ann Surg Oncol. 2012 Jul;19 Suppl 3:S656-64. doi: 10.1245/s10434-012-2217-6. Epub 2012 Feb 4.

PMID:
22311119
17.

The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer.

Smith AL, Iwanaga R, Drasin DJ, Micalizzi DS, Vartuli RL, Tan AC, Ford HL.

Oncogene. 2012 Dec 13;31(50):5162-71. doi: 10.1038/onc.2012.11. Epub 2012 Jan 30.

18.

miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes.

Perdigão-Henriques R, Petrocca F, Altschuler G, Thomas MP, Le MT, Tan SM, Hide W, Lieberman J.

Oncogene. 2016 Jan 14;35(2):158-72. doi: 10.1038/onc.2015.69. Epub 2015 Mar 23.

PMID:
25798844
19.
20.

MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination.

Lu M, Jolly MK, Levine H, Onuchic JN, Ben-Jacob E.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18144-9. doi: 10.1073/pnas.1318192110. Epub 2013 Oct 23.

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