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IL-2 contributes to maintaining a balance between CD4+Foxp3+ regulatory T cells and effector CD4+ T cells required for immune control of blood-stage malaria infection.

Berretta F, St-Pierre J, Piccirillo CA, Stevenson MM.

J Immunol. 2011 Apr 15;186(8):4862-71. doi: 10.4049/jimmunol.1003777. Epub 2011 Mar 9.


Anti-IL-2 treatment impairs the expansion of T(reg) cell population during acute malaria and enhances the Th1 cell response at the chronic disease.

Zago CA, Bortoluci KR, Sardinha LR, Pretel FD, Castillo-Méndez SI, Freitas do Rosário AP, Hiyane MI, Muxel SM, Rodriguez-Málaga SM, Abrahamsohn IA, Álvarez JM, D'Império Lima MR.

PLoS One. 2012;7(1):e29894. doi: 10.1371/journal.pone.0029894. Epub 2012 Jan 17.


Transient attenuated Foxp3 expression on CD4⁺ T cells treated with 7D4 mAb contributes to the control of parasite burden in DBA / 2 mice infected with lethal Plasmodium chabaudi chabaudi AS.

Feng H, Zhu XT, Qi ZM, Wang QH, Wang GG, Pan YY, Li Y, Zheng L, Jiang YJ, Shang H, Cui L, Cao YM.

Scand J Immunol. 2012 Jan;75(1):46-53. doi: 10.1111/j.1365-3083.2011.02622.x.


Plasmodium chabaudi AS: distinct CD4(+)CD25(+)Foxp3(+) regulatory T cell responses during infection in DBA/2 and BALB/c mice.

Wang GG, Chen G, Feng H, Liu J, Jiang YJ, Shang H, Cao YM.

Parasitol Int. 2013 Feb;62(1):24-31. doi: 10.1016/j.parint.2012.08.005. Epub 2012 Aug 27.


Concurrent infection with Heligmosomoides polygyrus suppresses anti-Plasmodium yoelii protection partially by induction of CD4(+)CD25(+)Foxp3(+) Treg in mice.

Tetsutani K, Ishiwata K, Ishida H, Tu L, Torii M, Hamano S, Himeno K, Hisaeda H.

Eur J Immunol. 2009 Oct;39(10):2822-30. doi: 10.1002/eji.200939433.


Downregulation of CD4+CD25+ regulatory T cells may underlie enhanced Th1 immunity caused by immunization with activated autologous T cells.

Cao Q, Wang L, Du F, Sheng H, Zhang Y, Wu J, Shen B, Shen T, Zhang J, Li D, Li N.

Cell Res. 2007 Jul;17(7):627-37.


Natural killer cells prevent CD28-mediated Foxp3 transcription in CD4+CD25- T lymphocytes.

Brillard E, Pallandre JR, Chalmers D, Ryffel B, Radlovic A, Seilles E, Rohrlich PS, Pivot X, Tiberghien P, Saas P, Borg C.

Exp Hematol. 2007 Mar;35(3):416-25.


Changes of CD4+CD25+Foxp3+ regulatory T cells in aged Balb/c mice.

Zhao L, Sun L, Wang H, Ma H, Liu G, Zhao Y.

J Leukoc Biol. 2007 Jun;81(6):1386-94. Epub 2007 Mar 16.


Strong impact of CD4+ Foxp3+ regulatory T cells and limited effect of T cell-derived IL-10 on pathogen clearance during Plasmodium yoelii infection.

Abel S, Lückheide N, Westendorf AM, Geffers R, Roers A, Müller W, Sparwasser T, Matuschewski K, Buer J, Hansen W.

J Immunol. 2012 Jun 1;188(11):5467-77. doi: 10.4049/jimmunol.1102223. Epub 2012 Apr 27.


IL-2 induces in vivo suppression by CD4(+)CD25(+)Foxp3(+) regulatory T cells.

Brandenburg S, Takahashi T, de la Rosa M, Janke M, Karsten G, Muzzulini T, Orinska Z, Bulfone-Paus S, Scheffold A.

Eur J Immunol. 2008 Jun;38(6):1643-53. doi: 10.1002/eji.200737791.


Stimulation of α7 nicotinic acetylcholine receptor by nicotine increases suppressive capacity of naturally occurring CD4+CD25+ regulatory T cells in mice in vitro.

Wang DW, Zhou RB, Yao YM, Zhu XM, Yin YM, Zhao GJ, Dong N, Sheng ZY.

J Pharmacol Exp Ther. 2010 Dec;335(3):553-61. doi: 10.1124/jpet.110.169961. Epub 2010 Sep 15.


An instructive role of donor macrophages in mixed chimeras in the induction of recipient CD4(+)Foxp3(+) Treg cells.

Liu G, Duan K, Ma H, Niu Z, Peng J, Zhao Y.

Immunol Cell Biol. 2011 Nov;89(8):827-35. doi: 10.1038/icb.2011.65. Epub 2011 Aug 16.


The immunoregulatory role of CD4⁺ FoxP3⁺ CD25⁻ regulatory T cells in lungs of mice infected with Bordetella pertussis.

Coleman MM, Finlay CM, Moran B, Keane J, Dunne PJ, Mills KH.

FEMS Immunol Med Microbiol. 2012 Apr;64(3):413-24. doi: 10.1111/j.1574-695X.2011.00927.x. Epub 2012 Jan 18.


Short-term anti-CD25 monoclonal antibody treatment and neogenetic CD4(+)CD25(high) regulatory T cells in kidney transplantation.

Wang Z, Xiao L, Shi BY, Qian YY, Bai HW, Chang JY, Cai M.

Transpl Immunol. 2008 Apr;19(1):69-73. doi: 10.1016/j.trim.2008.01.005. Epub 2008 Feb 22.


Control of Schistosoma mansoni egg-induced inflammation by IL-4-responsive CD4(+)CD25(-)CD103(+)Foxp3(-) cells is IL-10-dependent.

Dewals B, Hoving JC, Horsnell WG, Brombacher F.

Eur J Immunol. 2010 Oct;40(10):2837-47. doi: 10.1002/eji.200940075.


A possible role of CD4+CD25+ T cells as well as transcription factor Foxp3 in the dysregulation of allergic rhinitis.

Xu G, Mou Z, Jiang H, Cheng L, Shi J, Xu R, Oh Y, Li H.

Laryngoscope. 2007 May;117(5):876-80.


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