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Items: 1 to 20 of 96

1.

Cleavage of oxidized guanine nucleotide and ADP sugar by human NUDT5 protein.

Ito R, Sekiguchi M, Setoyama D, Nakatsu Y, Yamagata Y, Hayakawa H.

J Biochem. 2011 Jun;149(6):731-8. doi: 10.1093/jb/mvr028.

PMID:
21389046
2.

A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides.

Ishibashi T, Hayakawa H, Sekiguchi M.

EMBO Rep. 2003 May;4(5):479-83.

3.

Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base.

Nakamura T, Meshitsuka S, Kitagawa S, Abe N, Yamada J, Ishino T, Nakano H, Tsuzuki T, Doi T, Kobayashi Y, Fujii S, Sekiguchi M, Yamagata Y.

J Biol Chem. 2010 Jan 1;285(1):444-52. doi: 10.1074/jbc.M109.066373.

4.

NDX-1 protein hydrolyzes 8-oxo-7, 8-dihydrodeoxyguanosine-5'-diphosphate to sanitize oxidized nucleotides and prevent oxidative stress in Caenorhabditis elegans.

Sanada U, Yonekura S, Kikuchi M, Hashiguchi K, Nakamura N, Yonei S, Zhang-Akiyama QM.

J Biochem. 2011 Dec;150(6):649-57. doi: 10.1093/jb/mvr107.

PMID:
21873335
5.

Diverse substrate recognition and hydrolysis mechanisms of human NUDT5.

Arimori T, Tamaoki H, Nakamura T, Kamiya H, Ikemizu S, Takagi Y, Ishibashi T, Harashima H, Sekiguchi M, Yamagata Y.

Nucleic Acids Res. 2011 Nov 1;39(20):8972-83. doi: 10.1093/nar/gkr575.

6.

Human MTH3 (NUDT18) protein hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates: comparison with MTH1 and MTH2.

Takagi Y, Setoyama D, Ito R, Kamiya H, Yamagata Y, Sekiguchi M.

J Biol Chem. 2012 Jun 15;287(25):21541-9. doi: 10.1074/jbc.M112.363010.

7.

Mammalian enzymes for preventing transcriptional errors caused by oxidative damage.

Ishibashi T, Hayakawa H, Ito R, Miyazawa M, Yamagata Y, Sekiguchi M.

Nucleic Acids Res. 2005 Jul 7;33(12):3779-84.

8.

NUDT5 hydrolyzes oxidized deoxyribonucleoside diphosphates with broad substrate specificity.

Kamiya H, Hori M, Arimori T, Sekiguchi M, Yamagata Y, Harashima H.

DNA Repair (Amst). 2009 Oct 2;8(10):1250-4. doi: 10.1016/j.dnarep.2009.07.011.

PMID:
19699693
9.

Lowered nudix type 5 (NUDT5) expression leads to cell cycle retardation in HeLa cells.

Zhang LQ, Dai DP, Gan W, Takagi Y, Hayakawa H, Sekiguchi M, Cai JP.

Mol Cell Biochem. 2012 Apr;363(1-2):377-84. doi: 10.1007/s11010-011-1190-x.

PMID:
22200976
10.

Lowered Nudix type 5 expression leads to cellular senescence in IMR-90 fibroblast cells.

Zhang L, Song XN, Dai DP, Zhou XY, Gan W, Takagi Y, Hayakawa H, Sekiguchi M, Cai JP.

Free Radic Res. 2013 Jul;47(6-7):511-6. doi: 10.3109/10715762.2013.795221.

PMID:
23581889
11.

Suppression of mutagenesis by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate (7,8-dihydro-8-oxo-2'-deoxyguanosine 5'-triphosphate) by human MTH1, MTH2, and NUDT5.

Hori M, Satou K, Harashima H, Kamiya H.

Free Radic Biol Med. 2010 May 1;48(9):1197-201. doi: 10.1016/j.freeradbiomed.2010.02.002.

PMID:
20144704
12.

Potential of Escherichia coli GTP cyclohydrolase II for hydrolyzing 8-oxo-dGTP, a mutagenic substrate for DNA synthesis.

Kobayashi M, Ohara-Nemoto Y, Kaneko M, Hayakawa H, Sekiguchi M, Yamamoto K.

J Biol Chem. 1998 Oct 9;273(41):26394-9.

13.

A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1.

Sakai Y, Furuichi M, Takahashi M, Mishima M, Iwai S, Shirakawa M, Nakabeppu Y.

J Biol Chem. 2002 Mar 8;277(10):8579-87.

14.

Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools.

Ito R, Hayakawa H, Sekiguchi M, Ishibashi T.

Biochemistry. 2005 May 3;44(17):6670-4.

PMID:
15850400
15.

Interactions of the products, 8-oxo-dGMP, dGMP, and pyrophosphate with the MutT nucleoside triphosphate pyrophosphohydrolase.

Saraswat V, Massiah MA, Lopez G, Amzel LM, Mildvan AS.

Biochemistry. 2002 Dec 31;41(52):15566-77.

PMID:
12501185
16.

The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein.

Fujikawa K, Kamiya H, Yakushiji H, Fujii Y, Nakabeppu Y, Kasai H.

J Biol Chem. 1999 Jun 25;274(26):18201-5.

17.

Interactions of nucleotide cofactors with the Escherichia coli replication factor DnaC protein.

Galletto R, Rajendran S, Bujalowski W.

Biochemistry. 2000 Oct 24;39(42):12959-69.

PMID:
11041861
18.

Activation of NUDT5, an ADP-ribose pyrophosphatase, by nitric oxide-mediated ADP-ribosylation.

Yu HN, Song EK, Yoo SM, Lee YR, Han MK, Yim CY, Kwak JY, Kim JS.

Biochem Biophys Res Commun. 2007 Mar 16;354(3):764-8.

PMID:
17261271
19.

Crystal structures of human NUDT5 reveal insights into the structural basis of the substrate specificity.

Zha M, Zhong C, Peng Y, Hu H, Ding J.

J Mol Biol. 2006 Dec 15;364(5):1021-33.

PMID:
17052728
20.

Molecular mechanism of ADP-ribose hydrolysis by human NUDT5 from structural and kinetic studies.

Zha M, Guo Q, Zhang Y, Yu B, Ou Y, Zhong C, Ding J.

J Mol Biol. 2008 Jun 6;379(3):568-78. doi: 10.1016/j.jmb.2008.04.006.

PMID:
18462755
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