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Items: 1 to 20 of 96

1.

Mechanisms of aneuploidy and its suppression by tumour suppressor proteins.

Thoma CR, Toso A, Meraldi P, Krek W.

Swiss Med Wkly. 2011 Mar 8;141:w13170. doi: 10.4414/smw.2011.13170. Review.

2.

Chromosome instability and deregulated proliferation: an unavoidable duo.

Coschi CH, Dick FA.

Cell Mol Life Sci. 2012 Jun;69(12):2009-24. doi: 10.1007/s00018-011-0910-4. Review.

PMID:
22223110
3.

Double-trouble in mitosis caused by von Hippel-Lindau tumor-suppressor protein inactivation.

Thoma CR, Toso A, Meraldi P, Krek W.

Cell Cycle. 2009 Nov 15;8(22):3619-20. No abstract available.

PMID:
19884795
4.
5.

Mouse models in tumor suppression.

Ghebranious N, Donehower LA.

Oncogene. 1998 Dec 24;17(25):3385-400. Review.

6.

The impact of p53 and p73 on aneuploidy and cancer.

Tomasini R, Mak TW, Melino G.

Trends Cell Biol. 2008 May;18(5):244-52. doi: 10.1016/j.tcb.2008.03.003. Review.

PMID:
18406616
7.

Tumor suppressors APC and VHL: gatekeepers of the intestine and kidney.

Giles RH, Voest EE.

Prog Mol Subcell Biol. 2005;40:151-81. Review. No abstract available.

PMID:
17153484
8.

The positive regulation of p53 by the tumor suppressor VHL.

Roe JS, Youn HD.

Cell Cycle. 2006 Sep;5(18):2054-6. Review.

PMID:
16969113
9.

Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice.

Albers J, Rajski M, Schönenberger D, Harlander S, Schraml P, von Teichman A, Georgiev S, Wild PJ, Moch H, Krek W, Frew IJ.

EMBO Mol Med. 2013 Jun;5(6):949-64. doi: 10.1002/emmm.201202231.

10.

p53: guardian of ploidy.

Aylon Y, Oren M.

Mol Oncol. 2011 Aug;5(4):315-23. doi: 10.1016/j.molonc.2011.07.007. Review.

11.

Role of the p53 family in stabilizing the genome and preventing polyploidization.

Talos F, Moll UM.

Adv Exp Med Biol. 2010;676:73-91. Review.

PMID:
20687470
12.

Low levels of p27 in association with deregulated p53-pRb protein status enhance tumor proliferation and chromosomal instability in non-small cell lung carcinomas.

Tsoli E, Gorgoulis VG, Zacharatos P, Kotsinas A, Mariatos G, Kastrinakis NG, Kokotas S, Kanavaros P, Asimacopoulos P, Bramis J, Kletsas D, Papavassiliou AG, Kittas C.

Mol Med. 2001 Jun;7(6):418-29.

13.

The role of tumor suppressor dysregulation in prostate cancer progression.

Dean JL, Knudsen KE.

Curr Drug Targets. 2013 Apr;14(4):460-71. Review.

PMID:
23410128
14.

Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation.

Manning AL, Benes C, Dyson NJ.

Oncogene. 2014 May 8;33(19):2487-94. doi: 10.1038/onc.2013.201.

15.

MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation.

Lentini L, Barra V, Schillaci T, Di Leonardo A.

J Cell Physiol. 2012 Sep;227(9):3324-32. doi: 10.1002/jcp.24030.

PMID:
22170163
16.

Tumour suppression: putting on the brakes.

Harris H.

Nature. 2004 Jan 15;427(6971):201. No abstract available.

PMID:
14724616
17.

RB: mitotic implications of a tumour suppressor.

Manning AL, Dyson NJ.

Nat Rev Cancer. 2012 Feb 9;12(3):220-6. doi: 10.1038/nrc3216. Review.

18.

Altered expression of the cell cycle regulatory molecules pRb, p53 and MDM2 exert a synergetic effect on tumor growth and chromosomal instability in non-small cell lung carcinomas (NSCLCs).

Gorgoulis VG, Zacharatos P, Kotsinas A, Mariatos G, Liloglou T, Vogiatzi T, Foukas P, Rassidakis G, Garinis G, Ioannides T, Zoumpourlis V, Bramis J, Michail PO, Asimacopoulos PJ, Field JK, Kittas C.

Mol Med. 2000 Mar;6(3):208-37. Erratum in: Mol Med 2001 Dec;7(12):861.

19.

Cell cycle checkpoint-guarded routes to catenation-induced chromosomal instability.

Smith PJ, Chin SF, Njoh K, Khan IA, Chappell MJ, Errington RJ.

SEB Exp Biol Ser. 2008;59:219-42. No abstract available.

PMID:
18368926
20.

Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.

Thompson SL, Compton DA.

J Cell Biol. 2010 Feb 8;188(3):369-81. doi: 10.1083/jcb.200905057.

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