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Items: 1 to 20 of 162


Mutations in zebrafish lrp2 result in adult-onset ocular pathogenesis that models myopia and other risk factors for glaucoma.

Veth KN, Willer JR, Collery RF, Gray MP, Willer GB, Wagner DS, Mullins MC, Udvadia AJ, Smith RS, John SW, Gregg RG, Link BA.

PLoS Genet. 2011 Feb;7(2):e1001310. doi: 10.1371/journal.pgen.1001310. Epub 2011 Feb 17.


Retinal proliferation response in the buphthalmic zebrafish, bugeye.

Sherpa T, Hunter SS, Frey RA, Robison BD, Stenkamp DL.

Exp Eye Res. 2011 Oct;93(4):424-36. doi: 10.1016/j.exer.2011.06.001. Epub 2011 Jun 15.


Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia.

Cases O, Joseph A, Obry A, Santin MD, Ben-Yacoub S, Pâques M, Amsellem-Levera S, Bribian A, Simonutti M, Augustin S, Debeir T, Sahel JA, Christ A, de Castro F, Lehéricy S, Cosette P, Kozyraki R.

PLoS One. 2015 Jun 24;10(6):e0129518. doi: 10.1371/journal.pone.0129518. eCollection 2015.


DRP1 inhibition rescues retinal ganglion cells and their axons by preserving mitochondrial integrity in a mouse model of glaucoma.

Kim KY, Perkins GA, Shim MS, Bushong E, Alcasid N, Ju S, Ellisman MH, Weinreb RN, Ju WK.

Cell Death Dis. 2015 Aug 6;6:e1839. doi: 10.1038/cddis.2015.180.


Mice with an induced mutation in collagen 8A2 develop larger eyes and are resistant to retinal ganglion cell damage in an experimental glaucoma model.

Steinhart MR, Cone FE, Nguyen C, Nguyen TD, Pease ME, Puk O, Graw J, Oglesby EN, Quigley HA.

Mol Vis. 2012;18:1093-106. Epub 2012 May 1.


The distinct optic disk and peripapillary appearance in Donnai-Barrow syndrome.

Khan AO, Ghazi NG.

Ophthalmic Genet. 2018 Jun;39(3):321-324. doi: 10.1080/13816810.2018.1430245. Epub 2018 Feb 1.


Broadening the phenotype of LRP2 mutations: a new mutation in LRP2 causes a predominantly ocular phenotype suggestive of Stickler syndrome.

Schrauwen I, Sommen M, Claes C, Pinner J, Flaherty M, Collins F, Van Camp G.

Clin Genet. 2014 Sep;86(3):282-6. doi: 10.1111/cge.12265. Epub 2013 Sep 23.


Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice.

Mao M, Smith RS, Alavi MV, Marchant JK, Cosma M, Libby RT, John SW, Gould DB.

Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6823-31. doi: 10.1167/iovs.15-17527.


The bugeye mutant zebrafish exhibits visual deficits that arise with the onset of an enlarged eye phenotype.

Stujenske JM, Dowling JE, Emran F.

Invest Ophthalmol Vis Sci. 2011 Jun 13;52(7):4200-7. doi: 10.1167/iovs.10-6434.


Challenges In Early Glaucoma Detection.

Dervisevic E, Pavljasevic S, Dervisevic A, Kasumovic SS.

Med Arch. 2016 Jun;70(3):203-7. doi: 10.5455/medarh.2016.70.203-207. Epub 2016 May 31.


Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy.

Nickells RW, Howell GR, Soto I, John SW.

Annu Rev Neurosci. 2012;35:153-79. doi: 10.1146/annurev.neuro.051508.135728. Epub 2012 Apr 12. Review.


Retinal ganglion cell loss in a rat ocular hypertension model is sectorial and involves early optic nerve axon loss.

Soto I, Pease ME, Son JL, Shi X, Quigley HA, Marsh-Armstrong N.

Invest Ophthalmol Vis Sci. 2011 Jan 21;52(1):434-41. doi: 10.1167/iovs.10-5856. Print 2011 Jan.


Radiation pretreatment does not protect the rat optic nerve from elevated intraocular pressure-induced injury.

Johnson EC, Cepurna WO, Choi D, Choe TE, Morrison JC.

Invest Ophthalmol Vis Sci. 2014 Dec 18;56(1):412-9. doi: 10.1167/iovs.14-15094.


Comparison between axonal and retinal ganglion cell gene expression in various optic nerve injuries including glaucoma.

Levkovitch-Verbin H, Makarovsky D, Vander S.

Mol Vis. 2013 Dec 16;19:2526-41. eCollection 2013.


Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the retinal ganglion cell layer.

Umali J, Hawkey-Noble A, French CR.

Vision Res. 2019 Mar;156:66-72. doi: 10.1016/j.visres.2019.01.008. Epub 2019 Feb 2.


Neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma.

Stankowska DL, Minton AZ, Rutledge MA, Mueller BH 2nd, Phatak NR, He S, Ma HY, Forster MJ, Yorio T, Krishnamoorthy RR.

Invest Ophthalmol Vis Sci. 2015 Jan 13;56(2):893-907. doi: 10.1167/iovs.14-15008.


Susceptibility to glaucoma damage related to age and connective tissue mutations in mice.

Steinhart MR, Cone-Kimball E, Nguyen C, Nguyen TD, Pease ME, Chakravarti S, Oglesby EN, Quigley HA.

Exp Eye Res. 2014 Feb;119:54-60. doi: 10.1016/j.exer.2013.12.008. Epub 2013 Dec 22.


Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma.

Pease ME, McKinnon SJ, Quigley HA, Kerrigan-Baumrind LA, Zack DJ.

Invest Ophthalmol Vis Sci. 2000 Mar;41(3):764-74.


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