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Items: 1 to 20 of 103

1.

Naphthalene-based RNA editing inhibitor blocks RNA editing activities and editosome assembly in Trypanosoma brucei.

Moshiri H, Acoca S, Kala S, Najafabadi HS, Hogues H, Purisima E, Salavati R.

J Biol Chem. 2011 Apr 22;286(16):14178-89. doi: 10.1074/jbc.M110.199646. Epub 2011 Mar 4.

2.

High resolution crystal structure of a key editosome enzyme from Trypanosoma brucei: RNA editing ligase 1.

Deng J, Schnaufer A, Salavati R, Stuart KD, Hol WG.

J Mol Biol. 2004 Oct 22;343(3):601-13.

PMID:
15465048
3.

Mutational analysis of Trypanosoma brucei RNA editing ligase reveals regions critical for interaction with KREPA2.

Mehta V, Sen R, Moshiri H, Salavati R.

PLoS One. 2015 Mar 19;10(3):e0120844. doi: 10.1371/journal.pone.0120844. eCollection 2015.

4.

Separate insertion and deletion subcomplexes of the Trypanosoma brucei RNA editing complex.

Schnaufer A, Ernst NL, Palazzo SS, O'Rear J, Salavati R, Stuart K.

Mol Cell. 2003 Aug;12(2):307-19.

5.

Novel TUTase associates with an editosome-like complex in mitochondria of Trypanosoma brucei.

Aphasizheva I, Ringpis GE, Weng J, Gershon PD, Lathrop RH, Aphasizhev R.

RNA. 2009 Jul;15(7):1322-37. doi: 10.1261/rna.1538809. Epub 2009 May 22.

6.

Differential Editosome Protein Function between Life Cycle Stages of Trypanosoma brucei.

McDermott SM, Guo X, Carnes J, Stuart K.

J Biol Chem. 2015 Oct 9;290(41):24914-31. doi: 10.1074/jbc.M115.669432. Epub 2015 Aug 24.

7.

Toward understanding the conformational dynamics of RNA ligation.

Swift RV, Durrant J, Amaro RE, McCammon JA.

Biochemistry. 2009 Feb 3;48(4):709-19. doi: 10.1021/bi8018114.

8.

Purification of a functional enzymatic editing complex from Trypanosoma brucei mitochondria.

Rusché LN, Cruz-Reyes J, Piller KJ, Sollner-Webb B.

EMBO J. 1997 Jul 1;16(13):4069-81.

9.

Structure of the mitochondrial editosome-like complex associated TUTase 1 reveals divergent mechanisms of UTP selection and domain organization.

Stagno J, Aphasizheva I, Bruystens J, Luecke H, Aphasizhev R.

J Mol Biol. 2010 Jun 11;399(3):464-75. doi: 10.1016/j.jmb.2010.04.021. Epub 2010 Apr 18.

10.

A fluorescence-based reporter substrate for monitoring RNA editing in trypanosomatid pathogens.

Moshiri H, Salavati R.

Nucleic Acids Res. 2010 Jul;38(13):e138. doi: 10.1093/nar/gkq333. Epub 2010 May 5.

11.

KREPA4, an RNA binding protein essential for editosome integrity and survival of Trypanosoma brucei.

Salavati R, Ernst NL, O'Rear J, Gilliam T, Tarun S Jr, Stuart K.

RNA. 2006 May;12(5):819-31. Epub 2006 Apr 6.

12.

A deletion site editing endonuclease in Trypanosoma brucei.

Trotter JR, Ernst NL, Carnes J, Panicucci B, Stuart K.

Mol Cell. 2005 Nov 11;20(3):403-12.

13.

The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.

Park YJ, Budiarto T, Wu M, Pardon E, Steyaert J, Hol WG.

Nucleic Acids Res. 2012 Aug;40(14):6966-77. doi: 10.1093/nar/gks369. Epub 2012 May 4.

14.

TbMP44 is essential for RNA editing and structural integrity of the editosome in Trypanosoma brucei.

Wang B, Ernst NL, Palazzo SS, Panigrahi AK, Salavati R, Stuart K.

Eukaryot Cell. 2003 Jun;2(3):578-87.

15.

RNA editing: complexity and complications.

Stuart K, Panigrahi AK.

Mol Microbiol. 2002 Aug;45(3):591-6. Review.

16.

Pilot-scale compound screening against RNA editing identifies trypanocidal agents.

Moshiri H, Mehta V, Yip CW, Salavati R.

J Biomol Screen. 2015 Jan;20(1):92-100. doi: 10.1177/1087057114548833. Epub 2014 Aug 28.

PMID:
25170016
17.

Structure and intrinsic disorder of the proteins of the Trypanosoma brucei editosome.

Czerwoniec A, Kasprzak JM, Bytner P, Dobrychłop M, Bujnicki JM.

FEBS Lett. 2015 Sep 14;589(19 Pt A):2603-10. doi: 10.1016/j.febslet.2015.07.026. Epub 2015 Jul 29. Review.

18.

Native mRNA editing complexes from Trypanosoma brucei mitochondria.

Pollard VW, Harris ME, Hajduk SL.

EMBO J. 1992 Dec;11(12):4429-38.

19.

Functional complementation of Trypanosoma brucei RNA in vitro editing with recombinant RNA ligase.

Gao G, Simpson AM, Kang X, Rogers K, Nebohacova M, Li F, Simpson L.

Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4712-7. Epub 2005 Mar 21.

20.

Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.

Deng J, Ernst NL, Turley S, Stuart KD, Hol WG.

EMBO J. 2005 Dec 7;24(23):4007-17. Epub 2005 Nov 10.

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