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Items: 1 to 20 of 109

1.

Disc1 point mutations in mice affect development of the cerebral cortex.

Lee FH, Fadel MP, Preston-Maher K, Cordes SP, Clapcote SJ, Price DJ, Roder JC, Wong AH.

J Neurosci. 2011 Mar 2;31(9):3197-206. doi: 10.1523/JNEUROSCI.4219-10.2011.

2.

Genetic inactivation of GSK3α rescues spine deficits in Disc1-L100P mutant mice.

Lee FH, Kaidanovich-Beilin O, Roder JC, Woodgett JR, Wong AH.

Schizophr Res. 2011 Jun;129(1):74-9. doi: 10.1016/j.schres.2011.03.032. Epub 2011 Apr 17.

PMID:
21498050
3.

Abnormal interneuron development in disrupted-in-schizophrenia-1 L100P mutant mice.

Lee FH, Zai CC, Cordes SP, Roder JC, Wong AH.

Mol Brain. 2013 Apr 30;6:20. doi: 10.1186/1756-6606-6-20.

4.

Altered Disrupted-in-Schizophrenia-1 Function Affects the Development of Cortical Parvalbumin Interneurons by an Indirect Mechanism.

Borkowska M, Millar JK, Price DJ.

PLoS One. 2016 May 31;11(5):e0156082. doi: 10.1371/journal.pone.0156082. eCollection 2016.

5.

Maternal immune activation during gestation interacts with Disc1 point mutation to exacerbate schizophrenia-related behaviors in mice.

Lipina TV, Zai C, Hlousek D, Roder JC, Wong AH.

J Neurosci. 2013 May 1;33(18):7654-66. doi: 10.1523/JNEUROSCI.0091-13.2013.

6.

Effects of background mutations and single nucleotide polymorphisms (SNPs) on the Disc1 L100P behavioral phenotype associated with schizophrenia in mice.

Arime Y, Fukumura R, Miura I, Mekada K, Yoshiki A, Wakana S, Gondo Y, Akiyama K.

Behav Brain Funct. 2014 Dec 8;10:45. doi: 10.1186/1744-9081-10-45.

7.

Comprehensive behavioral analysis of ENU-induced Disc1-Q31L and -L100P mutant mice.

Shoji H, Toyama K, Takamiya Y, Wakana S, Gondo Y, Miyakawa T.

BMC Res Notes. 2012 Feb 20;5:108. doi: 10.1186/1756-0500-5-108.

8.

Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.

Pletnikov MV, Ayhan Y, Nikolskaia O, Xu Y, Ovanesov MV, Huang H, Mori S, Moran TH, Ross CA.

Mol Psychiatry. 2008 Feb;13(2):173-86, 115. Epub 2007 Sep 11.

PMID:
17848917
9.

Disrupted-in-Schizophrenia 1 (DISC1) is necessary for the correct migration of cortical interneurons.

Steinecke A, Gampe C, Valkova C, Kaether C, Bolz J.

J Neurosci. 2012 Jan 11;32(2):738-45. doi: 10.1523/JNEUROSCI.5036-11.2012.

10.

DBZ regulates cortical cell positioning and neurite development by sustaining the anterograde transport of Lis1 and DISC1 through control of Ndel1 dual-phosphorylation.

Okamoto M, Iguchi T, Hattori T, Matsuzaki S, Koyama Y, Taniguchi M, Komada M, Xie MJ, Yagi H, Shimizu S, Konishi Y, Omi M, Yoshimi T, Tachibana T, Fujieda S, Katayama T, Ito A, Hirotsune S, Tohyama M, Sato M.

J Neurosci. 2015 Feb 18;35(7):2942-58. doi: 10.1523/JNEUROSCI.5029-13.2015.

11.

Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development.

Young-Pearse TL, Suth S, Luth ES, Sawa A, Selkoe DJ.

J Neurosci. 2010 Aug 4;30(31):10431-40. doi: 10.1523/JNEUROSCI.1445-10.2010.

12.

Disc1 variation leads to specific alterations in adult neurogenesis.

Chandran JS, Kazanis I, Clapcote SJ, Ogawa F, Millar JK, Porteous DJ, Ffrench-Constant C.

PLoS One. 2014 Oct 1;9(10):e108088. doi: 10.1371/journal.pone.0108088. eCollection 2014.

13.

Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.

Ayhan Y, Abazyan B, Nomura J, Kim R, Ladenheim B, Krasnova IN, Sawa A, Margolis RL, Cadet JL, Mori S, Vogel MW, Ross CA, Pletnikov MV.

Mol Psychiatry. 2011 Mar;16(3):293-306. doi: 10.1038/mp.2009.144. Epub 2010 Jan 5.

14.

Neuregulin-1 Regulates Cortical Inhibitory Neuron Dendrite and Synapse Growth through DISC1.

Unda BK, Kwan V, Singh KK.

Neural Plast. 2016;2016:7694385. Epub 2016 Oct 25.

15.
16.

Interaction between FEZ1 and DISC1 in regulation of neuronal development and risk for schizophrenia.

Kang E, Burdick KE, Kim JY, Duan X, Guo JU, Sailor KA, Jung DE, Ganesan S, Choi S, Pradhan D, Lu B, Avramopoulos D, Christian K, Malhotra AK, Song H, Ming GL.

Neuron. 2011 Nov 17;72(4):559-71. doi: 10.1016/j.neuron.2011.09.032.

17.

Frontal cortical synaptic communication is abnormal in Disc1 genetic mouse models of schizophrenia.

Holley SM, Wang EA, Cepeda C, Jentsch JD, Ross CA, Pletnikov MV, Levine MS.

Schizophr Res. 2013 May;146(1-3):264-72. doi: 10.1016/j.schres.2013.02.007. Epub 2013 Mar 6.

18.

Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.

Shen S, Lang B, Nakamoto C, Zhang F, Pu J, Kuan SL, Chatzi C, He S, Mackie I, Brandon NJ, Marquis KL, Day M, Hurko O, McCaig CD, Riedel G, St Clair D.

J Neurosci. 2008 Oct 22;28(43):10893-904. doi: 10.1523/JNEUROSCI.3299-08.2008.

19.

DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212.

Kim JY, Duan X, Liu CY, Jang MH, Guo JU, Pow-anpongkul N, Kang E, Song H, Ming GL.

Neuron. 2009 Sep 24;63(6):761-73. doi: 10.1016/j.neuron.2009.08.008.

20.

Interplay between DISC1 and GABA signaling regulates neurogenesis in mice and risk for schizophrenia.

Kim JY, Liu CY, Zhang F, Duan X, Wen Z, Song J, Feighery E, Lu B, Rujescu D, St Clair D, Christian K, Callicott JH, Weinberger DR, Song H, Ming GL.

Cell. 2012 Mar 2;148(5):1051-64. doi: 10.1016/j.cell.2011.12.037.

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