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Items: 1 to 20 of 82

1.

Direct effects of rapid-acting insulin analogues on insulin signaling in human pancreatic islets in vitro.

D'Aleo V, Mancarella R, Del Guerra S, Boggi U, Filipponi F, Marchetti P, Lupi R.

Diabetes Metab. 2011 Sep;37(4):324-9. doi: 10.1016/j.diabet.2010.12.002. Epub 2011 Feb 26.

PMID:
21354844
2.

Effects of prolonged exposure to pancreatic glucagon on the function, antigenicity and survival of isolated human islets.

Del Guerra S, Lupi R, Dotta F, Marselli L, Lencioni C, Santangelo C, Realacci M, Carmellini M, Mosca F, Navalesi R, Marchetti P.

Diabetes Metab Res Rev. 2000 Jul-Aug;16(4):281-6.

PMID:
10934457
3.

Effects of prolonged in vitro exposure to sulphonylureas on the function and survival of human islets.

Del Guerra S, Marselli L, Lupi R, Boggi U, Mosca F, Benzi L, Del Prato S, Marchetti P.

J Diabetes Complications. 2005 Jan-Feb;19(1):60-4.

PMID:
15642492
4.
5.

Glucose-regulated glucagon secretion requires insulin receptor expression in pancreatic alpha-cells.

Diao J, Asghar Z, Chan CB, Wheeler MB.

J Biol Chem. 2005 Sep 30;280(39):33487-96. Epub 2005 Jul 14.

6.

Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion.

Lupi R, Del Guerra S, Marselli L, Bugliani M, Boggi U, Mosca F, Marchetti P, Del Prato S.

Am J Physiol Endocrinol Metab. 2004 Apr;286(4):E560-7. Epub 2003 Nov 18.

7.

Palmitic acid increase levels of pancreatic duodenal homeobox-1 and p38/stress-activated protein kinase in islets from rats maintained on a low protein diet.

Arantes VC, Reis MA, Latorraca MQ, Ferreira F, Stoppiglia LF, Carneiro EM, Boschero AC.

Br J Nutr. 2006 Dec;96(6):1006-12.

PMID:
17181874
8.

A comparison of the steady-state pharmacokinetics and pharmacodynamics of a novel rapid-acting insulin analog, insulin glulisine, and regular human insulin in healthy volunteers using the euglycemic clamp technique.

Becker RH, Frick AD, Burger F, Scholtz H, Potgieter JH.

Exp Clin Endocrinol Diabetes. 2005 May;113(5):292-7. Erratum in: Exp Clin Endocrinol Diabetes. 2005 Jul;113(7):409.

PMID:
15926116
9.

The biguanide compound metformin prevents desensitization of human pancreatic islets induced by high glucose.

Lupi R, Del Guerra S, Tellini C, Giannarelli R, Coppelli A, Lorenzetti M, Carmellini M, Mosca F, Navalesi R, Marchetti P.

Eur J Pharmacol. 1999 Jan 8;364(2-3):205-9.

PMID:
9932725
10.

Advantage of premeal-injected insulin glulisine compared with regular human insulin in subjects with type 1 diabetes.

Rave K, Klein O, Frick AD, Becker RH.

Diabetes Care. 2006 Aug;29(8):1812-7.

PMID:
16873785
12.
13.
14.

Glucose- and insulin-induced phosphorylation of the insulin receptor and its primary substrates IRS-1 and IRS-2 in rat pancreatic islets.

Velloso LA, Carneiro EM, Crepaldi SC, Boschero AC, Saad MJ.

FEBS Lett. 1995 Dec 27;377(3):353-7.

16.

Insulin glulisine--a comprehensive preclinical evaluation.

Stammberger I, Seipke G, Bartels T.

Int J Toxicol. 2006 Jan-Feb;25(1):25-33.

PMID:
16510354
17.
18.

Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?

Welsh N, Cnop M, Kharroubi I, Bugliani M, Lupi R, Marchetti P, Eizirik DL.

Diabetes. 2005 Nov;54(11):3238-44.

19.

The non-peptidyl low molecular weight radical scavenger IAC protects human pancreatic islets from lipotoxicity.

D'Aleo V, Del Guerra S, Martano M, Bonamassa B, Canistro D, Soleti A, Valgimigli L, Paolini M, Filipponi F, Boggi U, Del Prato S, Lupi R.

Mol Cell Endocrinol. 2009 Oct 15;309(1-2):63-6. doi: 10.1016/j.mce.2009.05.010. Epub 2009 May 27.

PMID:
19481137
20.

Cytokine sensitivity of Langerhans' islets of diabetes-prone BB/OK rats under hypoglycemic conditions.

Schröder D, Wachlin G, Klöting I, Schmidt S.

Autoimmunity. 2003 Jun;36(4):211-9.

PMID:
14563014

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