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Items: 1 to 20 of 113

1.

Altered expression of Ano1 variants in human diabetic gastroparesis.

Mazzone A, Bernard CE, Strege PR, Beyder A, Galietta LJ, Pasricha PJ, Rae JL, Parkman HP, Linden DR, Szurszewski JH, Ördög T, Gibbons SJ, Farrugia G.

J Biol Chem. 2011 Apr 15;286(15):13393-403. doi: 10.1074/jbc.M110.196089.

2.

Ano1, a Ca2+-activated Cl- channel, coordinates contractility in mouse intestine by Ca2+ transient coordination between interstitial cells of Cajal.

Singh RD, Gibbons SJ, Saravanaperumal SA, Du P, Hennig GW, Eisenman ST, Mazzone A, Hayashi Y, Cao C, Stoltz GJ, Ordog T, Rock JR, Harfe BD, Szurszewski JH, Farrugia G.

J Physiol. 2014 Sep 15;592(18):4051-68. doi: 10.1113/jphysiol.2014.277152.

3.

Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles.

Hwang SJ, Blair PJ, Britton FC, O'Driscoll KE, Hennig G, Bayguinov YR, Rock JR, Harfe BD, Sanders KM, Ward SM.

J Physiol. 2009 Oct 15;587(Pt 20):4887-904. doi: 10.1113/jphysiol.2009.176198.

4.

Intracellular Ca(2+) release from endoplasmic reticulum regulates slow wave currents and pacemaker activity of interstitial cells of Cajal.

Zhu MH, Sung TS, O'Driscoll K, Koh SD, Sanders KM.

Am J Physiol Cell Physiol. 2015 Apr 15;308(8):C608-20. doi: 10.1152/ajpcell.00360.2014.

5.

A novel exon in the human Ca2+-activated Cl- channel Ano1 imparts greater sensitivity to intracellular Ca2.

Strege PR, Bernard CE, Mazzone A, Linden DR, Beyder A, Gibbons SJ, Farrugia G.

Am J Physiol Gastrointest Liver Physiol. 2015 Nov 1;309(9):G743-9. doi: 10.1152/ajpgi.00074.2015.

6.

A Ca(2+)-activated Cl(-) conductance in interstitial cells of Cajal linked to slow wave currents and pacemaker activity.

Zhu MH, Kim TW, Ro S, Yan W, Ward SM, Koh SD, Sanders KM.

J Physiol. 2009 Oct 15;587(Pt 20):4905-18. doi: 10.1113/jphysiol.2009.176206.

7.

Anoctamins and gastrointestinal smooth muscle excitability.

Sanders KM, Zhu MH, Britton F, Koh SD, Ward SM.

Exp Physiol. 2012 Feb;97(2):200-6. doi: 10.1113/expphysiol.2011.058248. Review.

8.

Computational modeling of anoctamin 1 calcium-activated chloride channels as pacemaker channels in interstitial cells of Cajal.

Lees-Green R, Gibbons SJ, Farrugia G, Sneyd J, Cheng LK.

Am J Physiol Gastrointest Liver Physiol. 2014 Apr 15;306(8):G711-27. doi: 10.1152/ajpgi.00449.2013.

9.

Inhibition of cell proliferation by a selective inhibitor of the Ca(2+)-activated Cl(-) channel, Ano1.

Mazzone A, Eisenman ST, Strege PR, Yao Z, Ordog T, Gibbons SJ, Farrugia G.

Biochem Biophys Res Commun. 2012 Oct 19;427(2):248-53. doi: 10.1016/j.bbrc.2012.09.022.

10.

Use of anoctamin 1 (ANO1) to evaluate interstitial cells of Cajal in Hirschsprung's disease.

Coyle D, Kelly DA, O'Donnell AM, Gillick J, Puri P.

Pediatr Surg Int. 2016 Feb;32(2):125-33. doi: 10.1007/s00383-015-3822-9.

PMID:
26510736
11.

Immunoreactivity for Ano1 detects depletion of Kit-positive interstitial cells of Cajal in patients with slow transit constipation.

Kashyap P, Gomez-Pinilla PJ, Pozo MJ, Cima RR, Dozois EJ, Larson DW, Ordog T, Gibbons SJ, Farrugia G.

Neurogastroenterol Motil. 2011 Aug;23(8):760-5. doi: 10.1111/j.1365-2982.2011.01729.x.

12.

Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6).

Mazzone A, Gibbons SJ, Bernard CE, Nowsheen S, Middha S, Almada LL, Ordog T, Kendrick ML, Reid Lombardo KM, Shen KR, Galietta LJ, Fernandez-Zapico ME, Farrugia G.

FASEB J. 2015 Jan;29(1):152-63. doi: 10.1096/fj.14-258541.

13.

Platelet-derived growth factor receptor α (PDGFRα)-expressing "fibroblast-like cells" in diabetic and idiopathic gastroparesis of humans.

Grover M, Bernard CE, Pasricha PJ, Parkman HP, Abell TL, Nguyen LA, Snape W, Shen KR, Sarr M, Swain J, Kendrick M, Gibbons S, Ordog T, Farrugia G.

Neurogastroenterol Motil. 2012 Sep;24(9):844-52. doi: 10.1111/j.1365-2982.2012.01944.x.

14.
15.

Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract.

Gomez-Pinilla PJ, Gibbons SJ, Bardsley MR, Lorincz A, Pozo MJ, Pasricha PJ, Van de Rijn M, West RB, Sarr MG, Kendrick ML, Cima RR, Dozois EJ, Larson DW, Ordog T, Farrugia G.

Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1370-81. doi: 10.1152/ajpgi.00074.2009.

16.
17.

Association of low numbers of CD206-positive cells with loss of ICC in the gastric body of patients with diabetic gastroparesis.

Bernard CE, Gibbons SJ, Mann IS, Froschauer L, Parkman HP, Harbison S, Abell TL, Snape WJ, Hasler WL, McCallum RW, Sarosiek I, Nguyen LA, Koch KL, Tonascia J, Hamilton FA, Kendrick ML, Shen KR, Pasricha PJ, Farrugia G; NIDDK Gastroparesis Clinical Research Consortium (GpCRC)..

Neurogastroenterol Motil. 2014 Sep;26(9):1275-84. doi: 10.1111/nmo.12389.

18.

Ano1 is a better marker than c-Kit for transcript analysis of single interstitial cells of Cajal in culture.

Loera-Valencia R, Wang XY, Wright GW, Barajas-López C, Huizinga JD.

Cell Mol Biol Lett. 2014 Dec;19(4):601-10. doi: 10.2478/s11658-014-0214-4.

PMID:
25338768
19.

Ano1 as a regulator of proliferation.

Stanich JE, Gibbons SJ, Eisenman ST, Bardsley MR, Rock JR, Harfe BD, Ordog T, Farrugia G.

Am J Physiol Gastrointest Liver Physiol. 2011 Dec;301(6):G1044-51. doi: 10.1152/ajpgi.00196.2011.

20.

Ultrastructural differences between diabetic and idiopathic gastroparesis.

Faussone-Pellegrini MS, Grover M, Pasricha PJ, Bernard CE, Lurken MS, Smyrk TC, Parkman HP, Abell TL, Snape WJ, Hasler WL, Unalp-Arida A, Nguyen L, Koch KL, Calles J, Lee L, Tonascia J, Hamilton FA, Farrugia G; NIDDK Gastroparesis Clinical Research Consortium (GpCRC)..

J Cell Mol Med. 2012 Jul;16(7):1573-81. doi: 10.1111/j.1582-4934.2011.01451.x.

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