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Items: 1 to 20 of 96

1.

DNA polymerase beta is critical for genomic stability of sperm cells.

Kidane D, Dalal S, Keh A, Liu Y, Zelterman D, Sweasy JB.

DNA Repair (Amst). 2011 Apr 3;10(4):390-7. doi: 10.1016/j.dnarep.2011.01.003. Epub 2011 Feb 18.

2.

R152C DNA Pol β mutation impairs base excision repair and induces cellular transformation.

Zhou T, Pan F, Cao Y, Han Y, Zhao J, Sun H, Zhou X, Wu X, He L, Hu Z, Chen H, Shen B, Guo Z.

Oncotarget. 2016 Feb 9;7(6):6902-15. doi: 10.18632/oncotarget.6849.

3.

Deregulated expression of DNA polymerase β is involved in the progression of genomic instability.

Luo Q, Lai Y, Liu S, Wu M, Liu Y, Zhang Z.

Environ Mol Mutagen. 2012 Jun;53(5):325-33. doi: 10.1002/em.21697. Epub 2012 May 10.

4.

Cellular roles of DNA polymerase beta.

Ray S, Menezes MR, Senejani A, Sweasy JB.

Yale J Biol Med. 2013 Dec 13;86(4):463-9. Review.

5.

Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens.

Cabelof DC, Guo Z, Raffoul JJ, Sobol RW, Wilson SH, Richardson A, Heydari AR.

Cancer Res. 2003 Sep 15;63(18):5799-807.

6.

Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo.

Cabelof DC, Raffoul JJ, Yanamadala S, Guo Z, Heydari AR.

Carcinogenesis. 2002 Sep;23(9):1419-25.

PMID:
12189182
7.

Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress.

Sobol RW, Watson DE, Nakamura J, Yakes FM, Hou E, Horton JK, Ladapo J, Van Houten B, Swenberg JA, Tindall KR, Samson LD, Wilson SH.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):6860-5. Epub 2002 Apr 30.

8.

[Research progress on DNA polymerase beta and genetic instability].

Wu M, Zhang Z.

Wei Sheng Yan Jiu. 2009 Sep;38(5):637-40. Review. Chinese.

PMID:
19877532
9.

DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.

Schrader CE, Linehan EK, Ucher AJ, Bertocci B, Stavnezer J.

DNA Repair (Amst). 2013 Dec;12(12):1087-93. doi: 10.1016/j.dnarep.2013.09.002. Epub 2013 Sep 29.

10.

Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity.

Guo Z, Zheng L, Dai H, Zhou M, Xu H, Shen B.

Nucleic Acids Res. 2009 Jun;37(10):3431-41. doi: 10.1093/nar/gkp201. Epub 2009 Mar 31.

11.

Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice.

Allen D, Herbert DC, McMahan CA, Rotrekl V, Sobol RW, Wilson SH, Walter CA.

Biol Reprod. 2008 Nov;79(5):824-31. doi: 10.1095/biolreprod.108.069104. Epub 2008 Jul 23.

12.

Involvement of DNA polymerase beta in repairing oxidative damages induced by antitumor drug adriamycin.

Liu S, Wu M, Zhang Z.

Toxicol Appl Pharmacol. 2010 Aug 1;246(3):163-70. doi: 10.1016/j.taap.2010.05.011. Epub 2010 May 25.

PMID:
20510258
13.

Mammalian DNA beta-polymerase in base excision repair of alkylation damage.

Sobol RW, Wilson SH.

Prog Nucleic Acid Res Mol Biol. 2001;68:57-74. Review.

PMID:
11554313
14.

Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation.

Nemec AA, Donigan KA, Murphy DL, Jaeger J, Sweasy JB.

J Biol Chem. 2012 Jul 6;287(28):23840-9. doi: 10.1074/jbc.M112.362111. Epub 2012 May 9.

16.

Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency.

Cabelof DC, Raffoul JJ, Nakamura J, Kapoor D, Abdalla H, Heydari AR.

J Biol Chem. 2004 Aug 27;279(35):36504-13. Epub 2004 Jun 24.

17.

Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates.

Senejani AG, Dalal S, Liu Y, Nottoli TP, McGrath JM, Clairmont CS, Sweasy JB.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6632-7. doi: 10.1073/pnas.1200800109. Epub 2012 Apr 9.

18.

Role of DNA polymerase beta in the genotoxicity of arsenic.

Lai Y, Zhao W, Chen C, Wu M, Zhang Z.

Environ Mol Mutagen. 2011 Jul;52(6):460-8. doi: 10.1002/em.20643. Epub 2011 Mar 2.

PMID:
21370284
19.

Loop II of DNA polymerase beta is important for polymerization activity and fidelity.

Lin GC, Jaeger J, Sweasy JB.

Nucleic Acids Res. 2007;35(9):2924-35. Epub 2007 Apr 16.

20.

Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate.

Cabelof DC, Ikeno Y, Nyska A, Busuttil RA, Anyangwe N, Vijg J, Matherly LH, Tucker JD, Wilson SH, Richardson A, Heydari AR.

Cancer Res. 2006 Aug 1;66(15):7460-5.

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