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Items: 1 to 20 of 101

1.

Structural and functional analysis of tomosyn identifies domains important in exocytotic regulation.

Williams AL, Bielopolski N, Meroz D, Lam AD, Passmore DR, Ben-Tal N, Ernst SA, Ashery U, Stuenkel EL.

J Biol Chem. 2011 Apr 22;286(16):14542-53. doi: 10.1074/jbc.M110.215624. Epub 2011 Feb 17.

2.

Differential interaction of tomosyn with syntaxin and SNAP25 depends on domains in the WD40 β-propeller core and determines its inhibitory activity.

Bielopolski N, Lam AD, Bar-On D, Sauer M, Stuenkel EL, Ashery U.

J Biol Chem. 2014 Jun 13;289(24):17087-99. doi: 10.1074/jbc.M113.515296. Epub 2014 Apr 29.

3.

The N- and C-terminal domains of tomosyn play distinct roles in soluble N-ethylmaleimide-sensitive factor attachment protein receptor binding and fusion regulation.

Yu H, Rathore SS, Gulbranson DR, Shen J.

J Biol Chem. 2014 Sep 12;289(37):25571-80. doi: 10.1074/jbc.M114.591487. Epub 2014 Jul 25.

4.

The R-SNARE motif of tomosyn forms SNARE core complexes with syntaxin 1 and SNAP-25 and down-regulates exocytosis.

Hatsuzawa K, Lang T, Fasshauer D, Bruns D, Jahn R.

J Biol Chem. 2003 Aug 15;278(33):31159-66. Epub 2003 Jun 2.

5.

Structural basis for the inhibitory role of tomosyn in exocytosis.

Pobbati AV, Razeto A, Böddener M, Becker S, Fasshauer D.

J Biol Chem. 2004 Nov 5;279(45):47192-200. Epub 2004 Aug 16.

6.

Receptor-mediated regulation of tomosyn-syntaxin 1A interactions in bovine adrenal chromaffin cells.

Gladycheva SE, Lam AD, Liu J, D'Andrea-Merrins M, Yizhar O, Lentz SI, Ashery U, Ernst SA, Stuenkel EL.

J Biol Chem. 2007 Aug 3;282(31):22887-99. Epub 2007 Jun 1.

7.
8.

Tomosyn interacts with the SUMO E3 ligase PIASγ.

Geerts CJ, Jacobsen L, van de Bospoort R, Verhage M, Groffen AJ.

PLoS One. 2014 Mar 10;9(3):e91697. doi: 10.1371/journal.pone.0091697. eCollection 2014.

9.

Tomosyn-1 is involved in a post-docking event required for pancreatic beta-cell exocytosis.

Cheviet S, Bezzi P, Ivarsson R, Renström E, Viertl D, Kasas S, Catsicas S, Regazzi R.

J Cell Sci. 2006 Jul 15;119(Pt 14):2912-20. Epub 2006 Jun 20.

10.

Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process.

Fujita Y, Shirataki H, Sakisaka T, Asakura T, Ohya T, Kotani H, Yokoyama S, Nishioka H, Matsuura Y, Mizoguchi A, Scheller RH, Takai Y.

Neuron. 1998 May;20(5):905-15.

11.

Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release.

Sakisaka T, Yamamoto Y, Mochida S, Nakamura M, Nishikawa K, Ishizaki H, Okamoto-Tanaka M, Miyoshi J, Fujiyoshi Y, Manabe T, Takai Y.

J Cell Biol. 2008 Oct 20;183(2):323-37. doi: 10.1083/jcb.200805150.

12.

Three splicing variants of tomosyn and identification of their syntaxin-binding region.

Yokoyama S, Shirataki H, Sakisaka T, Takai Y.

Biochem Biophys Res Commun. 1999 Mar 5;256(1):218-22.

PMID:
10066450
13.

Multiple functional domains are involved in tomosyn regulation of exocytosis.

Yizhar O, Lipstein N, Gladycheva SE, Matti U, Ernst SA, Rettig J, Stuenkel EL, Ashery U.

J Neurochem. 2007 Oct;103(2):604-16. Epub 2007 Jul 31.

14.

Amisyn regulates exocytosis and fusion pore stability by both syntaxin-dependent and syntaxin-independent mechanisms.

Constable JR, Graham ME, Morgan A, Burgoyne RD.

J Biol Chem. 2005 Sep 9;280(36):31615-23. Epub 2005 Jul 20.

15.

Tomosyn is expressed in beta-cells and negatively regulates insulin exocytosis.

Zhang W, Lilja L, Mandic SA, Gromada J, Smidt K, Janson J, Takai Y, Bark C, Berggren PO, Meister B.

Diabetes. 2006 Mar;55(3):574-81.

16.

Tomosyn Negatively Regulates Arginine Vasopressin Secretion in Embryonic Stem Cell-Derived Neurons.

Takeuchi S, Iwama S, Takagi H, Kiyota A, Nakashima K, Izumida H, Fujisawa H, Iwata N, Suga H, Watanabe T, Kaibuchi K, Oiso Y, Arima H, Sugimura Y.

PLoS One. 2016 Oct 12;11(10):e0164544. doi: 10.1371/journal.pone.0164544. eCollection 2016.

17.

Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion.

Bhatnagar S, Soni MS, Wrighton LS, Hebert AS, Zhou AS, Paul PK, Gregg T, Rabaglia ME, Keller MP, Coon JJ, Attie AD.

J Biol Chem. 2014 Sep 5;289(36):25276-86. doi: 10.1074/jbc.M114.575985. Epub 2014 Jul 7.

18.

A novel site of action for alpha-SNAP in the SNARE conformational cycle controlling membrane fusion.

Barszczewski M, Chua JJ, Stein A, Winter U, Heintzmann R, Zilly FE, Fasshauer D, Lang T, Jahn R.

Mol Biol Cell. 2008 Mar;19(3):776-84. Epub 2007 Dec 19.

19.

The tail domain of tomosyn controls membrane fusion through tomosyn displacement by VAMP2.

Yamamoto Y, Fujikura K, Sakaue M, Okimura K, Kobayashi Y, Nakamura T, Sakisaka T.

Biochem Biophys Res Commun. 2010 Aug 13;399(1):24-30. doi: 10.1016/j.bbrc.2010.07.026. Epub 2010 Jul 13.

PMID:
20633536
20.

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