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Items: 1 to 20 of 145


Membrane-coating lattice scaffolds in the nuclear pore and vesicle coats: commonalities, differences, challenges.

Leksa NC, Schwartz TU.

Nucleus. 2010 Jul-Aug;1(4):314-8. doi: 10.4161/nucl.1.4.11798. Epub 2010 Mar 12. Review.


Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice.

Brohawn SG, Schwartz TU.

Nat Struct Mol Biol. 2009 Nov;16(11):1173-7. doi: 10.1038/nsmb.1713. Epub 2009 Oct 25.


Structural evidence for common ancestry of the nuclear pore complex and vesicle coats.

Brohawn SG, Leksa NC, Spear ED, Rajashankar KR, Schwartz TU.

Science. 2008 Nov 28;322(5906):1369-73. doi: 10.1126/science.1165886. Epub 2008 Oct 30.


Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element.

Whittle JR, Schwartz TU.

J Biol Chem. 2009 Oct 9;284(41):28442-52. doi: 10.1074/jbc.M109.023580. Epub 2009 Aug 11.


Structure of the Sec13-Sec16 edge element, a template for assembly of the COPII vesicle coat.

Whittle JR, Schwartz TU.

J Cell Biol. 2010 Aug 9;190(3):347-61. doi: 10.1083/jcb.201003092.


A lattice model of the nuclear pore complex.

Brohawn SG, Schwartz TU.

Commun Integr Biol. 2009 May;2(3):205-7.


A fence-like coat for the nuclear pore membrane.

Debler EW, Ma Y, Seo HS, Hsia KC, Noriega TR, Blobel G, Hoelz A.

Mol Cell. 2008 Dec 26;32(6):815-26. doi: 10.1016/j.molcel.2008.12.001.


Structural evolution of the membrane-coating module of the nuclear pore complex.

Liu X, Mitchell JM, Wozniak RW, Blobel G, Fan J.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16498-503. doi: 10.1073/pnas.1214557109. Epub 2012 Sep 26.


The molecular architecture of the nuclear pore complex.

Alber F, Dokudovskaya S, Veenhoff LM, Zhang W, Kipper J, Devos D, Suprapto A, Karni-Schmidt O, Williams R, Chait BT, Sali A, Rout MP.

Nature. 2007 Nov 29;450(7170):695-701.


Integrative structure-function mapping of the nucleoporin Nup133 suggests a conserved mechanism for membrane anchoring of the nuclear pore complex.

Kim SJ, Fernandez-Martinez J, Sampathkumar P, Martel A, Matsui T, Tsuruta H, Weiss TM, Shi Y, Markina-Inarrairaegui A, Bonanno JB, Sauder JM, Burley SK, Chait BT, Almo SC, Rout MP, Sali A.

Mol Cell Proteomics. 2014 Nov;13(11):2911-26. doi: 10.1074/mcp.M114.040915. Epub 2014 Aug 19.


Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex.

Sampathkumar P, Kim SJ, Upla P, Rice WJ, Phillips J, Timney BL, Pieper U, Bonanno JB, Fernandez-Martinez J, Hakhverdyan Z, Ketaren NE, Matsui T, Weiss TM, Stokes DL, Sauder JM, Burley SK, Sali A, Rout MP, Almo SC.

Structure. 2013 Apr 2;21(4):560-71. doi: 10.1016/j.str.2013.02.005. Epub 2013 Mar 14.


Nup120: one more piece in the NPC puzzle.

Vetter IR.

Structure. 2009 Aug 12;17(8):1036-8. doi: 10.1016/j.str.2009.07.005.


Systematic Protein-Protein Interaction Analysis Reveals Intersubcomplex Contacts in the Nuclear Pore Complex.

Apelt L, Knockenhauer KE, Leksa NC, Benlasfer N, Schwartz TU, Stelzl U.

Mol Cell Proteomics. 2016 Aug;15(8):2594-606. doi: 10.1074/mcp.M115.054627. Epub 2016 May 18.


Nucleoporin's Like Charge Regions Are Major Regulators of FG Coverage and Dynamics Inside the Nuclear Pore Complex.

Peyro M, Soheilypour M, Ghavami A, Mofrad MR.

PLoS One. 2015 Dec 11;10(12):e0143745. doi: 10.1371/journal.pone.0143745. eCollection 2015.


Three-dimensional structure and flexibility of a membrane-coating module of the nuclear pore complex.

Kampmann M, Blobel G.

Nat Struct Mol Biol. 2009 Jul;16(7):782-8. doi: 10.1038/nsmb.1618. Epub 2009 Jun 7.


Simple fold composition and modular architecture of the nuclear pore complex.

Devos D, Dokudovskaya S, Williams R, Alber F, Eswar N, Chait BT, Rout MP, Sali A.

Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2172-7. Epub 2006 Feb 6.


Quantifying nucleoporin stoichiometry inside single nuclear pore complexes in vivo.

Mi L, Goryaynov A, Lindquist A, Rexach M, Yang W.

Sci Rep. 2015 Mar 23;5:9372. doi: 10.1038/srep09372.


Structural and functional studies of Nup107/Nup133 interaction and its implications for the architecture of the nuclear pore complex.

Boehmer T, Jeudy S, Berke IC, Schwartz TU.

Mol Cell. 2008 Jun 20;30(6):721-31. doi: 10.1016/j.molcel.2008.04.022.


Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex.

Bilokapic S, Schwartz TU.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15241-6. Epub 2012 Sep 5.


Linker Nups connect the nuclear pore complex inner ring with the outer ring and transport channel.

Fischer J, Teimer R, Amlacher S, Kunze R, Hurt E.

Nat Struct Mol Biol. 2015 Oct;22(10):774-81. doi: 10.1038/nsmb.3084. Epub 2015 Sep 7.


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