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Items: 1 to 20 of 117

1.

Comparative transcriptional pathway bioinformatic analysis of dietary restriction, Sir2, p53 and resveratrol life span extension in Drosophila.

Antosh M, Whitaker R, Kroll A, Hosier S, Chang C, Bauer J, Cooper L, Neretti N, Helfand SL.

Cell Cycle. 2011 Mar 15;10(6):904-11. Epub 2011 Mar 15.

2.

dSir2 and Dmp53 interact to mediate aspects of CR-dependent lifespan extension in D. melanogaster.

Bauer JH, Morris SN, Chang C, Flatt T, Wood JG, Helfand SL.

Aging (Albany NY). 2009 Jan;1(1):38-48.

3.

Comparative transcriptional profiling identifies takeout as a gene that regulates life span.

Bauer J, Antosh M, Chang C, Schorl C, Kolli S, Neretti N, Helfand SL.

Aging (Albany NY). 2010 May;2(5):298-310.

4.

Sir2 mediates longevity in the fly through a pathway related to calorie restriction.

Rogina B, Helfand SL.

Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15998-6003. Epub 2004 Nov 1.

5.

Life span extension and neuronal cell protection by Drosophila nicotinamidase.

Balan V, Miller GS, Kaplun L, Balan K, Chong ZZ, Li F, Kaplun A, VanBerkum MF, Arking R, Freeman DC, Maiese K, Tzivion G.

J Biol Chem. 2008 Oct 10;283(41):27810-9. doi: 10.1074/jbc.M804681200. Epub 2008 Aug 4.

6.
7.

dSir2 and longevity in Drosophila.

Frankel S, Ziafazeli T, Rogina B.

Exp Gerontol. 2011 May;46(5):391-6. doi: 10.1016/j.exger.2010.08.007. Epub 2010 Aug 20. Review.

8.

Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female Drosophila.

Hoffmann J, Romey R, Fink C, Yong L, Roeder T.

Aging (Albany NY). 2013 Apr;5(4):315-27.

9.

Extended longevity and survivorship during amino-acid starvation in a Drosophila Sir2 mutant heterozygote.

Slade JD, Staveley BE.

Genome. 2016 May;59(5):311-8. doi: 10.1139/gen-2015-0213. Epub 2016 Feb 22.

PMID:
27074822
10.

The longevity of sirtuins.

Sinclair D, Verdin E.

Cell Rep. 2012 Dec 27;2(6):1473-4. doi: 10.1016/j.celrep.2012.12.004.

11.

Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila.

Griswold AJ, Chang KT, Runko AP, Knight MA, Min KT.

Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8673-8. doi: 10.1073/pnas.0803837105. Epub 2008 Jun 17.

12.

Drosophila foxo acts in males to cause sexual-dimorphism in tissue-specific p53 life span effects.

Shen J, Tower J.

Exp Gerontol. 2010 Feb;45(2):97-105. doi: 10.1016/j.exger.2009.10.009. Epub 2009 Oct 17.

13.

Mechanism of human SIRT1 activation by resveratrol.

Borra MT, Smith BC, Denu JM.

J Biol Chem. 2005 Apr 29;280(17):17187-95. Epub 2005 Mar 4.

14.

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.

Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, Riesen M, Howard K, Neri C, Bedalov A, Kaeberlein M, Soti C, Partridge L, Gems D.

Nature. 2011 Sep 21;477(7365):482-5. doi: 10.1038/nature10296.

15.

Involvement of Drosophila Sir2-like genes in the regulation of life span.

Kusama S, Ueda R, Suda T, Nishihara S, Matsuura ET.

Genes Genet Syst. 2006 Oct;81(5):341-8.

16.

Increased expression of Drosophila Sir2 extends life span in a dose-dependent manner.

Whitaker R, Faulkner S, Miyokawa R, Burhenn L, Henriksen M, Wood JG, Helfand SL.

Aging (Albany NY). 2013 Sep;5(9):682-91.

17.

HST2 mediates SIR2-independent life-span extension by calorie restriction.

Lamming DW, Latorre-Esteves M, Medvedik O, Wong SN, Tsang FA, Wang C, Lin SJ, Sinclair DA.

Science. 2005 Sep 16;309(5742):1861-4. Epub 2005 Jul 28.

18.

dSir2 in the adult fat body, but not in muscles, regulates life span in a diet-dependent manner.

Banerjee KK, Ayyub C, Ali SZ, Mandot V, Prasad NG, Kolthur-Seetharam U.

Cell Rep. 2012 Dec 27;2(6):1485-91. doi: 10.1016/j.celrep.2012.11.013. Epub 2012 Dec 13.

19.

Sir2-independent life span extension by calorie restriction in yeast.

Kaeberlein M, Kirkland KT, Fields S, Kennedy BK.

PLoS Biol. 2004 Sep;2(9):E296. Epub 2004 Aug 24.

20.

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