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Items: 1 to 20 of 239

1.

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver.

Li Y, Xu S, Giles A, Nakamura K, Lee JW, Hou X, Donmez G, Li J, Luo Z, Walsh K, Guarente L, Zang M.

FASEB J. 2011 May;25(5):1664-79. doi: 10.1096/fj.10-173492. Epub 2011 Feb 14.

2.

Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice.

Latreille M, Laberge MK, Bourret G, Yamani L, Larose L.

Am J Physiol Endocrinol Metab. 2011 Mar;300(3):E423-34. doi: 10.1152/ajpendo.00088.2010. Epub 2010 Jun 29.

3.

Endoplasmic reticulum stress promotes LIPIN2-dependent hepatic insulin resistance.

Ryu D, Seo WY, Yoon YS, Kim YN, Kim SS, Kim HJ, Park TS, Choi CS, Koo SH.

Diabetes. 2011 Apr;60(4):1072-81. doi: 10.2337/db10-1046. Epub 2011 Feb 25.

4.

Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21.

Li Y, Wong K, Giles A, Jiang J, Lee JW, Adams AC, Kharitonenkov A, Yang Q, Gao B, Guarente L, Zang M.

Gastroenterology. 2014 Feb;146(2):539-49.e7. doi: 10.1053/j.gastro.2013.10.059. Epub 2013 Nov 1.

5.

SIRT1 attenuates palmitate-induced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150.

Jung TW, Lee KT, Lee MW, Ka KH.

Biochem Biophys Res Commun. 2012 Jun 1;422(2):229-32. doi: 10.1016/j.bbrc.2012.04.129. Epub 2012 Apr 30.

PMID:
22564731
6.

Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance.

Ye R, Jung DY, Jun JY, Li J, Luo S, Ko HJ, Kim JK, Lee AS.

Diabetes. 2010 Jan;59(1):6-16. doi: 10.2337/db09-0755. Epub 2009 Oct 6.

7.

AMPK activation prevents excess nutrient-induced hepatic lipid accumulation by inhibiting mTORC1 signaling and endoplasmic reticulum stress response.

Li H, Min Q, Ouyang C, Lee J, He C, Zou MH, Xie Z.

Biochim Biophys Acta. 2014 Sep;1842(9):1844-54. doi: 10.1016/j.bbadis.2014.07.002. Epub 2014 Jul 10.

8.

Resveratrol treatment restores peripheral insulin sensitivity in diabetic mice in a sirt1-independent manner.

González-Rodríguez Á, Santamaría B, Mas-Gutierrez JA, Rada P, Fernández-Millán E, Pardo V, Álvarez C, Cuadrado A, Ros M, Serrano M, Valverde ÁM.

Mol Nutr Food Res. 2015 Aug;59(8):1431-42. doi: 10.1002/mnfr.201400933. Epub 2015 Apr 28.

PMID:
25808216
9.

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice.

Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, Ferré P, Foufelle F.

J Clin Invest. 2009 May;119(5):1201-15. doi: 10.1172/JCI37007. Epub 2009 Apr 13.

10.

Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity.

Zhou B, Li C, Qi W, Zhang Y, Zhang F, Wu JX, Hu YN, Wu DM, Liu Y, Yan TT, Jing Q, Liu MF, Zhai QW.

Diabetologia. 2012 Jul;55(7):2032-43. doi: 10.1007/s00125-012-2539-8. Epub 2012 Apr 4.

PMID:
22476949
11.

Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation.

Dong H, Huang H, Yun X, Kim DS, Yue Y, Wu H, Sutter A, Chavin KD, Otterbein LE, Adams DB, Kim YB, Wang H.

Endocrinology. 2014 Mar;155(3):818-28. doi: 10.1210/en.2013-1667. Epub 2014 Jan 1.

12.

Inhibition of CYP4A reduces hepatic endoplasmic reticulum stress and features of diabetes in mice.

Park EC, Kim SI, Hong Y, Hwang JW, Cho GS, Cha HN, Han JK, Yun CH, Park SY, Jang IS, Lee ZW, Choi JS, Kim S, Kim GH.

Gastroenterology. 2014 Oct;147(4):860-9. doi: 10.1053/j.gastro.2014.06.039. Epub 2014 Jun 28. Erratum in: Gastroenterology. 2015 Aug;149(2):509.

PMID:
24983671
13.

Protective Effects of Alisma orientale Extract against Hepatic Steatosis via Inhibition of Endoplasmic Reticulum Stress.

Jang MK, Han YR, Nam JS, Han CW, Kim BJ, Jeong HS, Ha KT, Jung MH.

Int J Mol Sci. 2015 Nov 2;16(11):26151-65. doi: 10.3390/ijms161125944.

14.

Protein tyrosine phosphatase 1B and insulin resistance: role of endoplasmic reticulum stress/reactive oxygen species/nuclear factor kappa B axis.

Panzhinskiy E, Ren J, Nair S.

PLoS One. 2013 Oct 18;8(10):e77228. doi: 10.1371/journal.pone.0077228. eCollection 2013.

15.

FoxO1 links hepatic insulin action to endoplasmic reticulum stress.

Kamagate A, Kim DH, Zhang T, Slusher S, Gramignoli R, Strom SC, Bertera S, Ringquist S, Dong HH.

Endocrinology. 2010 Aug;151(8):3521-35. doi: 10.1210/en.2009-1306. Epub 2010 May 25.

16.

Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice.

Huang J, Jia Y, Fu T, Viswakarma N, Bai L, Rao MS, Zhu Y, Borensztajn J, Reddy JK.

FASEB J. 2012 Feb;26(2):628-38. doi: 10.1096/fj.11-194019. Epub 2011 Oct 18.

17.

Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice.

Han MS, Chung KW, Cheon HG, Rhee SD, Yoon CH, Lee MK, Kim KW, Lee MS.

Diabetes. 2009 Feb;58(2):329-36. doi: 10.2337/db08-0080.

18.

Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance.

Wang RH, Kim HS, Xiao C, Xu X, Gavrilova O, Deng CX.

J Clin Invest. 2011 Nov;121(11):4477-90. doi: 10.1172/JCI46243. Epub 2011 Oct 3.

19.

AdipoR2 is transcriptionally regulated by ER stress-inducible ATF3 in HepG2 human hepatocyte cells.

Koh IU, Lim JH, Joe MK, Kim WH, Jung MH, Yoon JB, Song J.

FEBS J. 2010 May;277(10):2304-17. doi: 10.1111/j.1742-4658.2010.07646.x.

20.

Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.

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