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Items: 1 to 20 of 119

1.

Tropomyosin position on F-actin revealed by EM reconstruction and computational chemistry.

Li XE, Tobacman LS, Mun JY, Craig R, Fischer S, Lehman W.

Biophys J. 2011 Feb 16;100(4):1005-13. doi: 10.1016/j.bpj.2010.12.3697.

2.

The structural dynamics of α-tropomyosin on F-actin shape the overlap complex between adjacent tropomyosin molecules.

Lehman W, Li XE, Orzechowski M, Fischer S.

Arch Biochem Biophys. 2014 Jun 15;552-553:68-73. doi: 10.1016/j.abb.2013.09.011. Epub 2013 Sep 23.

3.

A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle X-ray fibre diagrams from non-overlap muscle.

Poole KJ, Lorenz M, Evans G, Rosenbaum G, Pirani A, Craig R, Tobacman LS, Lehman W, Holmes KC.

J Struct Biol. 2006 Aug;155(2):273-84. Epub 2006 May 7.

PMID:
16793285
4.

Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments.

Lehman W, Hatch V, Korman V, Rosol M, Thomas L, Maytum R, Geeves MA, Van Eyk JE, Tobacman LS, Craig R.

J Mol Biol. 2000 Sep 22;302(3):593-606.

PMID:
10986121
5.

A periodic pattern of evolutionarily conserved basic and acidic residues constitutes the binding interface of actin-tropomyosin.

Barua B, Fagnant PM, Winkelmann DA, Trybus KM, Hitchcock-DeGregori SE.

J Biol Chem. 2013 Apr 5;288(14):9602-9. doi: 10.1074/jbc.M113.451161. Epub 2013 Feb 18.

6.

3-D image reconstruction of reconstituted smooth muscle thin filaments containing calponin: visualization of interactions between F-actin and calponin.

Hodgkinson JL, el-Mezgueldi M, Craig R, Vibert P, Marston SB, Lehman W.

J Mol Biol. 1997 Oct 17;273(1):150-9.

PMID:
9367753
7.

Ca(2+)-induced switching of troponin and tropomyosin on actin filaments as revealed by electron cryo-microscopy.

Narita A, Yasunaga T, Ishikawa T, Mayanagi K, Wakabayashi T.

J Mol Biol. 2001 Apr 27;308(2):241-61.

PMID:
11327765
8.

An atomic model of the unregulated thin filament obtained by X-ray fiber diffraction on oriented actin-tropomyosin gels.

Lorenz M, Poole KJ, Popp D, Rosenbaum G, Holmes KC.

J Mol Biol. 1995 Feb 10;246(1):108-19. Erratum in: J Mol Biol 1995 Jun 2;249(2):509.

PMID:
7853391
9.

The shape and flexibility of tropomyosin coiled coils: implications for actin filament assembly and regulation.

Li XE, Holmes KC, Lehman W, Jung H, Fischer S.

J Mol Biol. 2010 Jan 15;395(2):327-39. doi: 10.1016/j.jmb.2009.10.060. Epub 2009 Oct 31.

PMID:
19883661
10.

Cryo-EM structures of the actin:tropomyosin filament reveal the mechanism for the transition from C- to M-state.

Sousa DR, Stagg SM, Stroupe ME.

J Mol Biol. 2013 Nov 15;425(22):4544-55. doi: 10.1016/j.jmb.2013.08.020. Epub 2013 Sep 8.

11.

X-ray diffraction studies on oriented gels of vertebrate smooth muscle thin filaments.

Popp D, Holmes KC.

J Mol Biol. 1992 Mar 5;224(1):65-76.

PMID:
1532210
12.

Visualization of caldesmon on smooth muscle thin filaments.

Lehman W, Vibert P, Craig R.

J Mol Biol. 1997 Dec 5;274(3):310-7.

PMID:
9405141
13.

Structural basis for Ca2+-regulated muscle relaxation at interaction sites of troponin with actin and tropomyosin.

Murakami K, Yumoto F, Ohki SY, Yasunaga T, Tanokura M, Wakabayashi T.

J Mol Biol. 2005 Sep 9;352(1):178-201.

PMID:
16061251
14.

Electrostatic interaction map reveals a new binding position for tropomyosin on F-actin.

Rynkiewicz MJ, Schott V, Orzechowski M, Lehman W, Fischer S.

J Muscle Res Cell Motil. 2015 Dec;36(6):525-33. doi: 10.1007/s10974-015-9419-z. Epub 2015 Aug 19.

15.

Structure of the F-actin-tropomyosin complex.

von der Ecken J, Müller M, Lehman W, Manstein DJ, Penczek PA, Raunser S.

Nature. 2015 Mar 5;519(7541):114-7. doi: 10.1038/nature14033. Epub 2014 Dec 1.

16.

An atomic model of the thin filament in the relaxed and Ca2+-activated states.

Pirani A, Vinogradova MV, Curmi PM, King WA, Fletterick RJ, Craig R, Tobacman LS, Xu C, Hatch V, Lehman W.

J Mol Biol. 2006 Mar 31;357(3):707-17. Epub 2006 Jan 13.

PMID:
16469331
17.
18.

Three-dimensional image reconstruction of reconstituted smooth muscle thin filaments: effects of caldesmon.

Hodgkinson JL, Marston SB, Craig R, Vibert P, Lehman W.

Biophys J. 1997 Jun;72(6):2398-404.

19.

Tropomyosin positions in regulated thin filaments revealed by cryoelectron microscopy.

Xu C, Craig R, Tobacman L, Horowitz R, Lehman W.

Biophys J. 1999 Aug;77(2):985-92.

20.

Single particle analysis of relaxed and activated muscle thin filaments.

Pirani A, Xu C, Hatch V, Craig R, Tobacman LS, Lehman W.

J Mol Biol. 2005 Feb 25;346(3):761-72. Epub 2005 Jan 11.

PMID:
15713461

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