Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 91

1.

Synthesis and biological evaluation of analogues of AKT (protein kinase B) inhibitor-IV.

Sun Q, Wu R, Cai S, Lin Y, Sellers L, Sakamoto K, He B, Peterson BR.

J Med Chem. 2011 Mar 10;54(5):1126-39. doi: 10.1021/jm100912b. Epub 2011 Feb 14.

2.

Anticancer/antiviral agent Akt inhibitor-IV massively accumulates in mitochondria and potently disrupts cellular bioenergetics.

Meinig JM, Peterson BR.

ACS Chem Biol. 2015 Feb 20;10(2):570-6. doi: 10.1021/cb500856c. Epub 2014 Dec 1.

3.

Synthesis, in vitro and in vivo antitumor and antiviral activity of novel 1-substituted benzimidazole derivatives.

Shaker YM, Omar MA, Mahmoud K, Elhallouty SM, El-Senousy WM, Ali MM, Mahmoud AE, Abdel-Halim AH, Soliman SM, El Diwani HI.

J Enzyme Inhib Med Chem. 2015;30(5):826-45. doi: 10.3109/14756366.2014.979344.

PMID:
25567722
4.

Synthesis and biological evaluation of imidazo[1,5-a]pyridine-benzimidazole hybrids as inhibitors of both tubulin polymerization and PI3K/Akt pathway.

Kamal A, Rao AV, Nayak VL, Reddy NV, Swapna K, Ramakrishna G, Alvala M.

Org Biomol Chem. 2014 Dec 28;12(48):9864-80. doi: 10.1039/c4ob01930j.

PMID:
25354805
5.

New thiazole carboxamides as potent inhibitors of Akt kinases.

Chang S, Zhang Z, Zhuang X, Luo J, Cao X, Li H, Tu Z, Lu X, Ren X, Ding K.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):1208-12. doi: 10.1016/j.bmcl.2011.11.080. Epub 2011 Nov 30.

PMID:
22172705
6.

Synthesis, antiviral and antitumor activity of 2-substituted-5-amidino-benzimidazoles.

Starcević K, Kralj M, Ester K, Sabol I, Grce M, Pavelić K, Karminski-Zamola G.

Bioorg Med Chem. 2007 Jul 1;15(13):4419-26. Epub 2007 Apr 25.

PMID:
17482821
7.

Synthesis and Biological Evaluation of 2-Aminobenzothiazole and Benzimidazole Analogs Based on the Clathrodin Structure.

Montalvão S, Leino TO, Kiuru PS, Lillsunde KE, Yli-Kauhaluoma J, Tammela P.

Arch Pharm (Weinheim). 2016 Feb;349(2):137-49. doi: 10.1002/ardp.201500365. Epub 2015 Dec 28.

PMID:
26709468
8.

Anti-HIV agents. I: Synthesis and in vitro anti-HIV evaluation of novel 1H,3H-thiazolo[3,4-a]benzimidazoles.

Chimirri A, Grasso S, Monforte AM, Monforte P, Zappalà M.

Farmaco. 1991 Jun;46(6):817-23.

PMID:
1685321
9.

Synthesis and antiviral/antiproliferative activity of some N-sulphonylbenzimidazoles.

Garuti L, Roberti M, De Clercq E.

Bioorg Med Chem Lett. 2002 Oct 7;12(19):2707-10.

PMID:
12217359
10.

A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate.

Falasca M, Chiozzotto D, Godage HY, Mazzoletti M, Riley AM, Previdi S, Potter BV, Broggini M, Maffucci T.

Br J Cancer. 2010 Jan 5;102(1):104-14. doi: 10.1038/sj.bjc.6605408.

11.

Synthesis, in vitro cytotoxic and antiviral activity of cis-[Pt(R(-) and S(+)-2-alpha-hydroxybenzylbenzimidazole)2Cl2] complexes.

Gökçe M, Utku S, Gür S, Ozkul A, Gümüş F.

Eur J Med Chem. 2005 Feb;40(2):135-41.

PMID:
15694648
12.

Anti-HIV agents II. Synthesis and in vitro anti-HIV activity of novel 1H,3H-thiazolo[3,4-a]benzimidazoles.

Chimirri A, Grasso S, Monforte AM, Monforte P, Zappala M.

Farmaco. 1991 Jul-Aug;46(7-8):925-33.

PMID:
1686551
13.

Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation.

Montagu A, Roy V, Balzarini J, Snoeck R, Andrei G, Agrofoglio LA.

Eur J Med Chem. 2011 Feb;46(2):778-86. doi: 10.1016/j.ejmech.2010.12.017. Epub 2010 Dec 21.

PMID:
21232828
14.

Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles.

Singh M, Tandon V.

Eur J Med Chem. 2011 Feb;46(2):659-69. doi: 10.1016/j.ejmech.2010.11.046. Epub 2010 Dec 8.

PMID:
21186067
15.

Derivatives containing both coumarin and benzimidazole potently induce caspase-dependent apoptosis of cancer cells through inhibition of PI3K-AKT-mTOR signaling.

Liu H, Wang Y, Sharma A, Mao R, Jiang N, Dun B, She JX.

Anticancer Drugs. 2015 Jul;26(6):667-77. doi: 10.1097/CAD.0000000000000232.

PMID:
25811964
16.

Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives.

Cheng J, Xie J, Luo X.

Bioorg Med Chem Lett. 2005 Jan 17;15(2):267-9.

PMID:
15603937
17.

Synthesis, structure and in vitro anti-human immunodeficiency virus activity of novel 3-methyl-1H,3H-thiazolo[3,4-a]benzimidazoles.

Chimirri A, Grasso S, Monforte AM, Monforte P, Rao A, Zappalà M, Bruno G, Nicolò F, Pannecouque C, Witvrouw M, De Clercq E.

Antivir Chem Chemother. 1998 Sep;9(5):431-8.

PMID:
9875396
18.

Synthesis and antiviral activity of novel 5-(1-cyanamido-2-haloethyl) and 5-(1-hydroxy(or methoxy)-2-azidoethyl) analogues of uracil nucleosides.

Kumar R, Rai D, Sharma SK, Saffran HA, Blush R, Tyrrell DL.

J Med Chem. 2001 Oct 11;44(21):3531-8.

PMID:
11585457
19.

DC120, a novel and potent inhibitor of AKT kinase, induces tumor cell apoptosis and suppresses tumor growth.

Deng R, Yang F, Chang SH, Tang J, Qin J, Feng GK, Ding K, Zhu XF.

Mol Pharmacol. 2012 Aug;82(2):189-98. doi: 10.1124/mol.111.077271. Epub 2012 May 2.

20.

Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides.

Quintiliani M, Persoons L, Solaroli N, Karlsson A, Andrei G, Snoeck R, Balzarini J, McGuigan C.

Bioorg Med Chem. 2011 Jul 15;19(14):4338-45. doi: 10.1016/j.bmc.2011.05.037. Epub 2011 May 27.

PMID:
21696963

Supplemental Content

Support Center