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Items: 1 to 20 of 91

1.

[Synthesis of secasterol and 24-episecasterol and their toxicity in MCF-7 cells].

Khripach VA, Zhabinskiĭ VN, Gyliakevich OV, Konstantinova OV, Misharin AIu, Mekhtiev AR, Timofeev VP, Tkachev IaV.

Bioorg Khim. 2010 Nov-Dec;36(6):815-24. Russian.

PMID:
21317948
2.

[(22R,23R)-3beta-Hydroxy-22,23-epoxy-5alpha-ergost-8(14)-en-15-one: improved synthesis and toxicity to MCF-7 cells].

Mekhtiev AR, Timofeev VP, Misharin AIu.

Bioorg Khim. 2008 Nov-Dec;34(6):840-6. Russian.

PMID:
19088760
3.

New pyrazolic compounds as cytotoxic agents.

Bouabdallah I, M'Barek LA, Zyad A, Ramdani A, Zidane I, Melhaoui A.

Nat Prod Res. 2007 Apr;21(4):298-302.

PMID:
17479417
4.

First stereoselective total synthesis and anticancer activity of new amide alkaloids of roots of pepper.

Srinivas Ch, Sai Pavan Kumar ChN, China Raju B, Jayathirtha Rao V, Naidu VG, Ramakrishna S, Diwan PV.

Bioorg Med Chem Lett. 2009 Oct 15;19(20):5915-8. doi: 10.1016/j.bmcl.2009.08.056. Epub 2009 Aug 20.

PMID:
19733069
5.

Isolation, synthesis and structures of cytotoxic ginsenoside derivatives.

Lei J, Li X, Gong XJ, Zheng YN.

Molecules. 2007 Sep 5;12(9):2140-50.

6.

Synthesis of a new cytotoxic cephalostatin/ritterazine analogue from hecogenin and 22-epi-hippuristanol.

Poza JJ, Rodríguez J, Jiménez C.

Bioorg Med Chem. 2010 Jan 1;18(1):58-63. doi: 10.1016/j.bmc.2009.11.018. Epub 2009 Nov 12.

PMID:
19948408
7.

Further study on synthesis and evaluation of 3,16,20-polyoxygenated steroids of marine origin and their analogs as potent cytotoxic agents.

Bunyathaworn P, Boonananwong S, Kongkathip B, Kongkathip N.

Steroids. 2010 Jun;75(6):432-44. doi: 10.1016/j.steroids.2010.02.011. Epub 2010 Feb 24.

PMID:
20188119
8.

Synthesis, proapoptotic screening, and structure-activity relationships of novel aza-lupane triterpenoids.

Mar AA, Szotek EL, Koohang A, Flavin WP, Eiznhamer DA, Flavin MT, Xu ZQ.

Bioorg Med Chem Lett. 2010 Sep 15;20(18):5389-93. doi: 10.1016/j.bmcl.2010.07.120. Epub 2010 Aug 3.

PMID:
20719505
9.

New quinoxaline 1,4-di-N-oxides. Part 1: Hypoxia-selective cytotoxins and anticancer agents derived from quinoxaline 1,4-di-N-oxides.

Amin KM, Ismail MM, Noaman E, Soliman DH, Ammar YA.

Bioorg Med Chem. 2006 Oct 15;14(20):6917-23. Epub 2006 Jul 14.

PMID:
16843668
10.

Synthesis and antitumor activity of new retinobenzoic acids.

Khandare RP, Vaze KR, Bhat SV.

Chem Biodivers. 2011 May;8(5):841-9. doi: 10.1002/cbdv.201000116.

PMID:
21560232
11.

Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines.

Karki R, Thapa P, Kang MJ, Jeong TC, Nam JM, Kim HL, Na Y, Cho WJ, Kwon Y, Lee ES.

Bioorg Med Chem. 2010 May 1;18(9):3066-77. doi: 10.1016/j.bmc.2010.03.051. Epub 2010 Mar 27.

PMID:
20392646
12.

Characterization, synthesis and self-aggregation of (-)-alternarlactam: a new fungal cytotoxin with cyclopentenone and isoquinolinone scaffolds.

Zhang AH, Jiang N, Gu W, Ma J, Wang YR, Song YC, Tan RX.

Chemistry. 2010 Dec 27;16(48):14479-85. doi: 10.1002/chem.201002205.

PMID:
21038331
13.

Antitumor activity of imidazothioxanthones in murine and human tumor models in vitro and in vivo.

Varvaresou A, Iakovou K, Gikas E, Fichtner I, Fiebig HH, Kelland LR, Double JA, Bibby MC, Hendriks HR.

Anticancer Res. 2004 Mar-Apr;24(2B):907-19.

14.

Benzothiepin-derived molecular scaffolds for estrogen receptor modulators: synthesis and antagonistic effects in breast cancer cells.

Meegan MJ, Barrett I, Zimmermann J, Knox AJ, Zisterer DM, Lloyd DG.

J Enzyme Inhib Med Chem. 2007 Oct;22(5):655-66.

PMID:
18035834
15.

Synthesis and evaluation of novel 4-amino-4,6-androstadiene-3,17-dione: an analog of formestane.

Sharma SK, Zheng W, Joshua AV, Abrams DN, McEwan AJ.

Bioorg Med Chem Lett. 2008 Oct 15;18(20):5563-6. doi: 10.1016/j.bmcl.2008.09.018. Epub 2008 Sep 22.

PMID:
18815032
16.

Synthesis and structure-activity relationships of fenbufen amide analogs.

Lin KI, Yang CH, Huang CW, Jian JY, Huang YC, Yu CS.

Molecules. 2010 Dec 2;15(12):8796-803. doi: 10.3390/molecules15128796.

17.

Synthesis and biological activity of novel shikonin analogues.

Wang W, Dai M, Zhu C, Zhang J, Lin L, Ding J, Duan W.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):735-7. doi: 10.1016/j.bmcl.2008.12.032. Epub 2008 Dec 11.

PMID:
19111464
18.

Novel naphthalimide-amino acid conjugates with flexible leucine moiety as side chain: design, synthesis and potential antitumor activity.

Wu A, Xu Y, Qian X.

Bioorg Med Chem. 2009 Jan 15;17(2):592-9. doi: 10.1016/j.bmc.2008.11.080. Epub 2008 Dec 7.

PMID:
19109022
19.

Synthesis, structure and hypoxic cytotoxicity of 3-amino-1,2,4-benzotriazine-1,4-dioxide derivatives.

Jiang F, Weng Q, Sheng R, Xia Q, He Q, Yang B, Hu Y.

Arch Pharm (Weinheim). 2007 May;340(5):258-63.

PMID:
17464965
20.

Synthesis, molecular modeling, and biological evaluation of cinnamic acid metronidazole ester derivatives as novel anticancer agents.

Qian Y, Zhang HJ, Zhang H, Xu C, Zhao J, Zhu HL.

Bioorg Med Chem. 2010 Jul 15;18(14):4991-6. doi: 10.1016/j.bmc.2010.06.003. Epub 2010 Jun 8.

PMID:
20594859

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