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Items: 1 to 20 of 268

1.

Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells.

Rodriguez BA, Weng YI, Liu TM, Zuo T, Hsu PY, Lin CH, Cheng AL, Cui H, Yan PS, Huang TH.

Carcinogenesis. 2011 Jun;32(6):812-21. doi: 10.1093/carcin/bgr017. Epub 2011 Feb 8.

2.

Silencing of imprinted CDKN1C gene expression is associated with loss of CpG and histone H3 lysine 9 methylation at DMR-LIT1 in esophageal cancer.

Soejima H, Nakagawachi T, Zhao W, Higashimoto K, Urano T, Matsukura S, Kitajima Y, Takeuchi M, Nakayama M, Oshimura M, Miyazaki K, Joh K, Mukai T.

Oncogene. 2004 May 27;23(25):4380-8.

PMID:
15007390
3.

Imprinting disruption of the CDKN1C/KCNQ1OT1 domain: the molecular mechanisms causing Beckwith-Wiedemann syndrome and cancer.

Higashimoto K, Soejima H, Saito T, Okumura K, Mukai T.

Cytogenet Genome Res. 2006;113(1-4):306-12.

PMID:
16575194
4.

Expression profile of LIT1/KCNQ1OT1 and epigenetic status at the KvDMR1 in colorectal cancers.

Nakano S, Murakami K, Meguro M, Soejima H, Higashimoto K, Urano T, Kugoh H, Mukai T, Ikeguchi M, Oshimura M.

Cancer Sci. 2006 Nov;97(11):1147-54. Epub 2006 Sep 5.

5.

A cross-talk between DNA methylation and H3 lysine 9 dimethylation at the KvDMR1 region controls the induction of Cdkn1c in muscle cells.

Andresini O, Ciotti A, Rossi MN, Battistelli C, Carbone M, Maione R.

Epigenetics. 2016 Nov;11(11):791-803. Epub 2016 Sep 9.

6.

Silencing of CDKN1C (p57KIP2) is associated with hypomethylation at KvDMR1 in Beckwith-Wiedemann syndrome.

Diaz-Meyer N, Day CD, Khatod K, Maher ER, Cooper W, Reik W, Junien C, Graham G, Algar E, Der Kaloustian VM, Higgins MJ.

J Med Genet. 2003 Nov;40(11):797-801.

7.

Two distinct mechanisms of silencing by the KvDMR1 imprinting control region.

Shin JY, Fitzpatrick GV, Higgins MJ.

EMBO J. 2008 Jan 9;27(1):168-78. Epub 2007 Dec 13.

8.

CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells.

Yang X, Karuturi RK, Sun F, Aau M, Yu K, Shao R, Miller LD, Tan PB, Yu Q.

PLoS One. 2009;4(4):e5011. doi: 10.1371/journal.pone.0005011. Epub 2009 Apr 2. Erratum in: PLoS One. 2009;4(4). doi: 10.1371/annotation/e70583a2-3581-4848-b1e3-b518ac07d3a6.

9.

Epigenetic down-regulation of CDKN1C/p57KIP2 in pancreatic ductal neoplasms identified by gene expression profiling.

Sato N, Matsubayashi H, Abe T, Fukushima N, Goggins M.

Clin Cancer Res. 2005 Jul 1;11(13):4681-8.

10.

ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome.

Arima T, Kamikihara T, Hayashida T, Kato K, Inoue T, Shirayoshi Y, Oshimura M, Soejima H, Mukai T, Wake N.

Nucleic Acids Res. 2005 May 11;33(8):2650-60. Print 2005.

11.

Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes.

Mancini-Dinardo D, Steele SJ, Levorse JM, Ingram RS, Tilghman SM.

Genes Dev. 2006 May 15;20(10):1268-82.

12.

Epigenetic silencing of the XAF1 gene is mediated by the loss of CTCF binding.

Victoria-Acosta G, Vazquez-Santillan K, Jimenez-Hernandez L, Muñoz-Galindo L, Maldonado V, Martinez-Ruiz GU, Melendez-Zajgla J.

Sci Rep. 2015 Oct 7;5:14838. doi: 10.1038/srep14838. Erratum in: Sci Rep. 2016;6:20462.

13.

Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c.

Asahara S, Etoh H, Inoue H, Teruyama K, Shibutani Y, Ihara Y, Kawada Y, Bartolome A, Hashimoto N, Matsuda T, Koyanagi-Kimura M, Kanno A, Hirota Y, Hosooka T, Nagashima K, Nishimura W, Inoue H, Matsumoto M, Higgins MJ, Yasuda K, Inagaki N, Seino S, Kasuga M, Kido Y.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8332-7. doi: 10.1073/pnas.1422104112. Epub 2015 Jun 22.

14.
15.

Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines.

Meeran SM, Patel SN, Tollefsbol TO.

PLoS One. 2010 Jul 6;5(7):e11457. doi: 10.1371/journal.pone.0011457.

16.

Gene methylation in gastric cancer.

Qu Y, Dang S, Hou P.

Clin Chim Acta. 2013 Sep 23;424:53-65. doi: 10.1016/j.cca.2013.05.002. Epub 2013 May 10. Review.

17.

Alternative mechanisms associated with silencing of CDKN1C in Beckwith-Wiedemann syndrome.

Diaz-Meyer N, Yang Y, Sait SN, Maher ER, Higgins MJ.

J Med Genet. 2005 Aug;42(8):648-55.

18.

Evolution of the CDKN1C-KCNQ1 imprinted domain.

Ager EI, Pask AJ, Gehring HM, Shaw G, Renfree MB.

BMC Evol Biol. 2008 May 29;8:163. doi: 10.1186/1471-2148-8-163.

19.

Enhancers compete with a long non-coding RNA for regulation of the Kcnq1 domain.

Schultz BM, Gallicio GA, Cesaroni M, Lupey LN, Engel N.

Nucleic Acids Res. 2015 Jan;43(2):745-59. doi: 10.1093/nar/gku1324. Epub 2014 Dec 24.

20.

A novel tetranucleotide repeat polymorphism within KCNQ1OT1 confers risk for hepatocellular carcinoma.

Wan J, Huang M, Zhao H, Wang C, Zhao X, Jiang X, Bian S, He Y, Gao Y.

DNA Cell Biol. 2013 Nov;32(11):628-34. doi: 10.1089/dna.2013.2118. Epub 2013 Aug 28.

PMID:
23984860

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