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Items: 1 to 20 of 125

1.

Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1.

Wu QQ, Wang Y, Senitko M, Meyer C, Wigley WC, Ferguson DA, Grossman E, Chen J, Zhou XJ, Hartono J, Winterberg P, Chen B, Agarwal A, Lu CY.

Am J Physiol Renal Physiol. 2011 May;300(5):F1180-92. doi: 10.1152/ajprenal.00353.2010. Epub 2011 Feb 2.

2.

Bardoxolone methyl (BARD) ameliorates aristolochic acid (AA)-induced acute kidney injury through Nrf2 pathway.

Wu J, Liu X, Fan J, Chen W, Wang J, Zeng Y, Feng X, Yu X, Yang X.

Toxicology. 2014 Apr 6;318:22-31. doi: 10.1016/j.tox.2014.01.008. Epub 2014 Feb 12.

PMID:
24530882
3.

Cilostazol attenuates murine hepatic ischemia and reperfusion injury via heme oxygenase-dependent activation of mitochondrial biogenesis.

Joe Y, Zheng M, Kim HJ, Uddin MJ, Kim SK, Chen Y, Park J, Cho GJ, Ryter SW, Chung HT.

Am J Physiol Gastrointest Liver Physiol. 2015 Jul 1;309(1):G21-9. doi: 10.1152/ajpgi.00307.2014. Epub 2015 May 7.

4.

The Nrf2 triterpenoid activator, CDDO-imidazolide, protects kidneys from ischemia-reperfusion injury in mice.

Liu M, Reddy NM, Higbee EM, Potteti HR, Noel S, Racusen L, Kensler TW, Sporn MB, Reddy SP, Rabb H.

Kidney Int. 2014 Jan;85(1):134-41. doi: 10.1038/ki.2013.357. Epub 2013 Oct 2.

5.

Hyperin inhibits nuclear factor kappa B and activates nuclear factor E2-related factor-2 signaling pathways in cisplatin-induced acute kidney injury in mice.

Chao CS, Tsai CS, Chang YP, Chen JM, Chin HK, Yang SC.

Int Immunopharmacol. 2016 Nov;40:517-523. doi: 10.1016/j.intimp.2016.09.020. Epub 2016 Oct 17.

PMID:
27764742
6.

Hepatic ischemia-reperfusion induces renal heme oxygenase-1 via NF-E2-related factor 2 in rats and mice.

Tanaka Y, Maher JM, Chen C, Klaassen CD.

Mol Pharmacol. 2007 Mar;71(3):817-25. Epub 2006 Dec 6.

7.

Signal transduction involved in lipoxin A4‑induced protection of tubular epithelial cells against hypoxia/reoxygenation injury.

Wu SH, Wang MJ, Lü J, Chen XQ.

Mol Med Rep. 2017 Apr;15(4):1682-1692. doi: 10.3892/mmr.2017.6195. Epub 2017 Feb 13.

8.

Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism.

Ferguson HE, Thatcher TH, Olsen KC, Garcia-Bates TM, Baglole CJ, Kottmann RM, Strong ER, Phipps RP, Sime PJ.

Am J Physiol Lung Cell Mol Physiol. 2009 Nov;297(5):L912-9. doi: 10.1152/ajplung.00148.2009. Epub 2009 Sep 4.

9.

Activation of nuclear factor erythroid 2-related factor 2 and PPARγ plays a role in the genistein-mediated attenuation of oxidative stress-induced endothelial cell injury.

Zhang T, Wang F, Xu HX, Yi L, Qin Y, Chang H, Mi MT, Zhang QY.

Br J Nutr. 2013 Jan 28;109(2):223-35. doi: 10.1017/S0007114512001110. Epub 2012 May 3.

PMID:
22716961
10.

ATF3-mediated NRF2/HO-1 signaling regulates TLR4 innate immune responses in mouse liver ischemia/reperfusion injury.

Rao J, Qian X, Li G, Pan X, Zhang C, Zhang F, Zhai Y, Wang X, Lu L.

Am J Transplant. 2015 Jan;15(1):76-87. doi: 10.1111/ajt.12954. Epub 2014 Oct 30.

11.

Nrf2 activator ameliorates hemorrhagic transformation in focal cerebral ischemia under warfarin anticoagulation.

Imai T, Takagi T, Kitashoji A, Yamauchi K, Shimazawa M, Hara H.

Neurobiol Dis. 2016 May;89:136-46. doi: 10.1016/j.nbd.2016.02.001. Epub 2016 Feb 2.

PMID:
26850917
12.

Penehyclidine Hydrochloride Pretreatment Ameliorates Rhabdomyolysis-Induced AKI by Activating the Nrf2/HO-1 Pathway and Alleviating [corrected] Endoplasmic Reticulum Stress in Rats. The.

Zhao W, Huang X, Zhang L, Yang X, Wang L, Chen Y, Wang J, Wu G.

PLoS One. 2016 Mar 17;11(3):e0151158. doi: 10.1371/journal.pone.0151158. eCollection 2016. Erratum in: PLoS One. 2016;11(4):e0154138.

13.

Electroacupuncture Ameliorates Acute Renal Injury in Lipopolysaccharide-Stimulated Rabbits via Induction of HO-1 through the PI3K/Akt/Nrf2 Pathways.

Yu JB, Shi J, Zhang Y, Gong LR, Dong SA, Cao XS, Wu LL, Wu LN.

PLoS One. 2015 Nov 2;10(11):e0141622. doi: 10.1371/journal.pone.0141622. eCollection 2015.

14.

Adoptive transfer of heme oxygenase-1 (HO-1)-modified macrophages rescues the nuclear factor erythroid 2-related factor (Nrf2) antiinflammatory phenotype in liver ischemia/reperfusion injury.

Huang J, Shen XD, Yue S, Zhu J, Gao F, Zhai Y, Busuttil RW, Ke B, Kupiec-Weglinski JW.

Mol Med. 2014 Oct 14;20:448-55. doi: 10.2119/molmed.2014.00103.

15.

CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes.

Reisman SA, Buckley DB, Tanaka Y, Klaassen CD.

Toxicol Appl Pharmacol. 2009 Apr 1;236(1):109-14. doi: 10.1016/j.taap.2008.12.024. Epub 2009 Jan 20.

16.

Cyclin-dependent kinase inhibitor p18INK4c is involved in protective roles of heme oxygenase-1 in cisplatin-induced acute kidney injury.

Wang L, Zhang Y, Yuan L, Liu C, Fu L, Mei C.

Int J Mol Med. 2014 Sep;34(3):911-7. doi: 10.3892/ijmm.2014.1828. Epub 2014 Jul 1.

PMID:
24993528
17.

Temporal activation of Nrf2 in the penumbra and Nrf2 activator-mediated neuroprotection in ischemia-reperfusion injury.

Takagi T, Kitashoji A, Iwawaki T, Tsuruma K, Shimazawa M, Yoshimura S, Iwama T, Hara H.

Free Radic Biol Med. 2014 Jul;72:124-33. doi: 10.1016/j.freeradbiomed.2014.04.009. Epub 2014 Apr 15.

PMID:
24746614
18.

Ankaflavin: a natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo.

Lee BH, Hsu WH, Chang YY, Kuo HF, Hsu YW, Pan TM.

Free Radic Biol Med. 2012 Dec 1;53(11):2008-16. doi: 10.1016/j.freeradbiomed.2012.09.025. Epub 2012 Sep 26.

PMID:
23022408
19.

Effects of captopril, telmisartan and bardoxolone methyl (CDDO-Me) in ischemia-reperfusion-induced acute kidney injury in rats: an experimental comparative study.

Kocak C, Kocak FE, Akcilar R, Bayat Z, Aras B, Metineren MH, Yucel M, Simsek H.

Clin Exp Pharmacol Physiol. 2016 Feb;43(2):230-41. doi: 10.1111/1440-1681.12511.

PMID:
26515498
20.

Bardoxolone methyl modulates efflux transporter and detoxifying enzyme expression in cisplatin-induced kidney cell injury.

Atilano-Roque A, Aleksunes LM, Joy MS.

Toxicol Lett. 2016 Sep 30;259:52-9. doi: 10.1016/j.toxlet.2016.07.021. Epub 2016 Jul 29.

PMID:
27480280

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