Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 84

1.

Comparative analysis of acid sphingomyelinase distribution in the CNS of rats and mice following intracerebroventricular delivery.

Treleaven CM, Tamsett T, Fidler JA, Taksir TV, Cheng SH, Shihabuddin LS, Dodge JC.

PLoS One. 2011 Jan 25;6(1):e16313. doi: 10.1371/journal.pone.0016313.

2.

Intracerebroventricular infusion of acid sphingomyelinase corrects CNS manifestations in a mouse model of Niemann-Pick A disease.

Dodge JC, Clarke J, Treleaven CM, Taksir TV, Griffiths DA, Yang W, Fidler JA, Passini MA, Karey KP, Schuchman EH, Cheng SH, Shihabuddin LS.

Exp Neurol. 2009 Feb;215(2):349-57. doi: 10.1016/j.expneurol.2008.10.021. Epub 2008 Nov 14.

PMID:
19059399
3.

Gene transfer of human acid sphingomyelinase corrects neuropathology and motor deficits in a mouse model of Niemann-Pick type A disease.

Dodge JC, Clarke J, Song A, Bu J, Yang W, Taksir TV, Griffiths D, Zhao MA, Schuchman EH, Cheng SH, O'Riordan CR, Shihabuddin LS, Passini MA, Stewart GR.

Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17822-7. Epub 2005 Nov 21.

4.

Intracerebral transplantation of adult mouse neural progenitor cells into the Niemann-Pick-A mouse leads to a marked decrease in lysosomal storage pathology.

Shihabuddin LS, Numan S, Huff MR, Dodge JC, Clarke J, Macauley SL, Yang W, Taksir TV, Parsons G, Passini MA, Gage FH, Stewart GR.

J Neurosci. 2004 Nov 24;24(47):10642-51.

5.

Intraparenchymal injections of acid sphingomyelinase results in regional correction of lysosomal storage pathology in the Niemann-Pick A mouse.

Yang WW, Dodge JC, Passini MA, Taksir TV, Griffiths D, Schuchman EH, Cheng SH, Shihabuddin LS.

Exp Neurol. 2007 Oct;207(2):258-66. Epub 2007 Jul 10.

PMID:
17686472
6.

Distribution of acid sphingomyelinase in rodent and non-human primate brain after intracerebroventricular infusion.

Ziegler RJ, Salegio EA, Dodge JC, Bringas J, Treleaven CM, Bercury SD, Tamsett TJ, Shihabuddin L, Hadaczek P, Fiandaca M, Bankiewicz K, Scheule RK.

Exp Neurol. 2011 Oct;231(2):261-71. doi: 10.1016/j.expneurol.2011.06.019. Epub 2011 Jul 14.

PMID:
21777586
7.

Merits of combination cortical, subcortical, and cerebellar injections for the treatment of Niemann-Pick disease type A.

Bu J, Ashe KM, Bringas J, Marshall J, Dodge JC, Cabrera-Salazar MA, Forsayeth J, Schuchman EH, Bankiewicz KS, Cheng SH, Shihabuddin LS, Passini MA.

Mol Ther. 2012 Oct;20(10):1893-901. doi: 10.1038/mt.2012.118. Epub 2012 Jul 24.

8.

AAV vector-mediated correction of brain pathology in a mouse model of Niemann-Pick A disease.

Passini MA, Macauley SL, Huff MR, Taksir TV, Bu J, Wu IH, Piepenhagen PA, Dodge JC, Shihabuddin LS, O'Riordan CR, Schuchman EH, Stewart GR.

Mol Ther. 2005 May;11(5):754-62.

9.

Safety study of adeno-associated virus serotype 2-mediated human acid sphingomyelinase expression in the nonhuman primate brain.

Salegio EA, Samaranch L, Jenkins RW, Clarke CJ, Lamarre C, Beyer J, Kells AP, Bringas J, Sebastian WS, Richardson RM, Rosenbluth KH, Hannun YA, Bankiewicz KS, Forsayeth J.

Hum Gene Ther. 2012 Aug;23(8):891-902. doi: 10.1089/hum.2012.052.

11.

Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of Niemann-Pick disease type A.

Buccinnà B, Piccinini M, Prinetti A, Scandroglio F, Prioni S, Valsecchi M, Votta B, Grifoni S, Lupino E, Ramondetti C, Schuchman EH, Giordana MT, Sonnino S, Rinaudo MT.

J Neurochem. 2009 Apr;109(1):105-15. doi: 10.1111/j.1471-4159.2009.05947.x. Epub 2009 Feb 2.

12.

Infusion of recombinant human acid sphingomyelinase into niemann-pick disease mice leads to visceral, but not neurological, correction of the pathophysiology.

Miranda SR, He X, Simonaro CM, Gatt S, Dagan A, Desnick RJ, Schuchman EH.

FASEB J. 2000 Oct;14(13):1988-95.

PMID:
11023983
13.

Neuropathology of the acid sphingomyelinase knockout mouse model of Niemann-Pick A disease including structure-function studies associated with cerebellar Purkinje cell degeneration.

Macauley SL, Sidman RL, Schuchman EH, Taksir T, Stewart GR.

Exp Neurol. 2008 Dec;214(2):181-92. doi: 10.1016/j.expneurol.2008.07.026. Epub 2008 Aug 16.

PMID:
18778708
14.
15.

Injection of mouse and human neural stem cells into neonatal Niemann-Pick A model mice.

Sidman RL, Li J, Stewart GR, Clarke J, Yang W, Snyder EY, Shihabuddin LS.

Brain Res. 2007 Apr 6;1140:195-204. Epub 2007 Jan 9.

PMID:
17289003
16.

Pulmonary delivery of recombinant acid sphingomyelinase improves clearance of lysosomal sphingomyelin from the lungs of a murine model of Niemann-Pick disease.

Ziegler RJ, Brown C, Barbon CM, D'Angona AM, Schuchman EH, Andrews L, Thurberg BL, McPherson JM, Karey KP, Cheng SH.

Mol Genet Metab. 2009 May;97(1):35-42. doi: 10.1016/j.ymgme.2009.01.008. Epub 2009 Jan 25.

PMID:
19231265
19.
20.

AAV8-mediated hepatic expression of acid sphingomyelinase corrects the metabolic defect in the visceral organs of a mouse model of Niemann-Pick disease.

Barbon CM, Ziegler RJ, Li C, Armentano D, Cherry M, Desnick RJ, Schuchman EH, Cheng SH.

Mol Ther. 2005 Sep;12(3):431-40.

Supplemental Content

Support Center