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Items: 1 to 20 of 111

1.

Effect of metformin therapy on cardiac function and survival in a volume-overload model of heart failure in rats.

Benes J, Kazdova L, Drahota Z, Houstek J, Medrikova D, Kopecky J, Kovarova N, Vrbacky M, Sedmera D, Strnad H, Kolar M, Petrak J, Benada O, Skaroupkova P, Cervenka L, Melenovsky V.

Clin Sci (Lond). 2011 Jul;121(1):29-41. doi: 10.1042/CS20100527.

PMID:
21275906
2.

Metabolic characterization of volume overload heart failure due to aorto-caval fistula in rats.

Melenovsky V, Benes J, Skaroupkova P, Sedmera D, Strnad H, Kolar M, Vlcek C, Petrak J, Benes J Jr, Papousek F, Oliyarnyk O, Kazdova L, Cervenka L.

Mol Cell Biochem. 2011 Aug;354(1-2):83-96. doi: 10.1007/s11010-011-0808-3.

PMID:
21465236
3.

Reverse changes in cardiac substrate oxidation in dogs recovering from heart failure.

Qanud K, Mamdani M, Pepe M, Khairallah RJ, Gravel J, Lei B, Gupte SA, Sharov VG, Sabbah HN, Stanley WC, Recchia FA.

Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2098-105. doi: 10.1152/ajpheart.00471.2008.

4.

Myocardial insulin resistance induced by high fat feeding in heart failure is associated with preserved contractile function.

Christopher BA, Huang HM, Berthiaume JM, McElfresh TA, Chen X, Croniger CM, Muzic RF Jr, Chandler MP.

Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1917-27. doi: 10.1152/ajpheart.00687.2010.

5.

Pioglitazone improves cardiac function and alters myocardial substrate metabolism without affecting cardiac triglyceride accumulation and high-energy phosphate metabolism in patients with well-controlled type 2 diabetes mellitus.

van der Meer RW, Rijzewijk LJ, de Jong HW, Lamb HJ, Lubberink M, Romijn JA, Bax JJ, de Roos A, Kamp O, Paulus WJ, Heine RJ, Lammertsma AA, Smit JW, Diamant M.

Circulation. 2009 Apr 21;119(15):2069-77. doi: 10.1161/CIRCULATIONAHA.108.803916.

6.

Metformin improves cardiac function in a nondiabetic rat model of post-MI heart failure.

Yin M, van der Horst IC, van Melle JP, Qian C, van Gilst WH, Silljé HH, de Boer RA.

Am J Physiol Heart Circ Physiol. 2011 Aug;301(2):H459-68. doi: 10.1152/ajpheart.00054.2011.

8.

Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure.

Gundewar S, Calvert JW, Jha S, Toedt-Pingel I, Ji SY, Nunez D, Ramachandran A, Anaya-Cisneros M, Tian R, Lefer DJ.

Circ Res. 2009 Feb 13;104(3):403-11. doi: 10.1161/CIRCRESAHA.108.190918.

9.

Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats.

Zhang CX, Pan SN, Meng RS, Peng CQ, Xiong ZJ, Chen BL, Chen GQ, Yao FJ, Chen YL, Ma YD, Dong YG.

Clin Exp Pharmacol Physiol. 2011 Jan;38(1):55-62. doi: 10.1111/j.1440-1681.2010.05461.x.

PMID:
21083698
10.

Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase.

Sasaki H, Asanuma H, Fujita M, Takahama H, Wakeno M, Ito S, Ogai A, Asakura M, Kim J, Minamino T, Takashima S, Sanada S, Sugimachi M, Komamura K, Mochizuki N, Kitakaze M.

Circulation. 2009 May 19;119(19):2568-77. doi: 10.1161/CIRCULATIONAHA.108.798561.

11.

Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overload.

Doenst T, Pytel G, Schrepper A, Amorim P, Färber G, Shingu Y, Mohr FW, Schwarzer M.

Cardiovasc Res. 2010 Jun 1;86(3):461-70. doi: 10.1093/cvr/cvp414.

PMID:
20035032
12.

Effect of metformin on glutathione and magnesium in normal and streptozotocin-induced diabetic rats.

Ewis SA, Abdel-Rahman MS.

J Appl Toxicol. 1995 Sep-Oct;15(5):387-90.

PMID:
8666722
13.

Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure.

Rennison JH, McElfresh TA, Okere IC, Patel HV, Foster AB, Patel KK, Stoll MS, Minkler PE, Fujioka H, Hoit BD, Young ME, Hoppel CL, Chandler MP.

Cardiovasc Res. 2008 Jul 15;79(2):331-40. doi: 10.1093/cvr/cvn066.

PMID:
18339649
14.
15.

Metformin improves cardiac function in rats via activation of AMP-activated protein kinase.

Wang XF, Zhang JY, Li L, Zhao XY, Tao HL, Zhang L.

Clin Exp Pharmacol Physiol. 2011 Feb;38(2):94-101. doi: 10.1111/j.1440-1681.2010.05470.x.

PMID:
21143620
16.

Control of oxidative metabolism in volume-overloaded rat hearts: effect of propionyl-L-carnitine.

El Alaoui-Talibi Z, Guendouz A, Moravec M, Moravec J.

Am J Physiol. 1997 Apr;272(4 Pt 2):H1615-24.

PMID:
9139943
17.

Impact of sex on the heart's metabolic and functional responses to diabetic therapies.

Lyons MR, Peterson LR, McGill JB, Herrero P, Coggan AR, Saeed IM, Recklein C, Schechtman KB, Gropler RJ.

Am J Physiol Heart Circ Physiol. 2013 Dec 1;305(11):H1584-91. doi: 10.1152/ajpheart.00420.2013.

18.

Chronic metformin associated cardioprotection against infarction: not just a glucose lowering phenomenon.

Whittington HJ, Hall AR, McLaughlin CP, Hausenloy DJ, Yellon DM, Mocanu MM.

Cardiovasc Drugs Ther. 2013 Feb;27(1):5-16. doi: 10.1007/s10557-012-6425-x.

PMID:
23192487
19.

Tetradecylthioacetic acid increases fat metabolism and improves cardiac function in experimental heart failure.

Øie E, Berge RK, Ueland T, Dahl CP, Edvardsen T, Beitnes JO, Bohov P, Aukrust P, Yndestad A.

Lipids. 2013 Feb;48(2):139-54. doi: 10.1007/s11745-012-3749-z.

PMID:
23266898
20.
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