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Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury.

Hellal F, Hurtado A, Ruschel J, Flynn KC, Laskowski CJ, Umlauf M, Kapitein LC, Strikis D, Lemmon V, Bixby J, Hoogenraad CC, Bradke F.

Science. 2011 Feb 18;331(6019):928-31. doi: 10.1126/science.1201148. Epub 2011 Jan 27.


Pharmacological Suppression of CNS Scarring by Deferoxamine Reduces Lesion Volume and Increases Regeneration in an In Vitro Model for Astroglial-Fibrotic Scarring and in Rat Spinal Cord Injury In Vivo.

Vogelaar CF, König B, Krafft S, Estrada V, Brazda N, Ziegler B, Faissner A, Müller HW.

PLoS One. 2015 Jul 29;10(7):e0134371. doi: 10.1371/journal.pone.0134371. eCollection 2015.


Axonal regeneration. Systemic administration of epothilone B promotes axon regeneration after spinal cord injury.

Ruschel J, Hellal F, Flynn KC, Dupraz S, Elliott DA, Tedeschi A, Bates M, Sliwinski C, Brook G, Dobrindt K, Peitz M, Brüstle O, Norenberg MD, Blesch A, Weidner N, Bunge MB, Bixby JL, Bradke F.

Science. 2015 Apr 17;348(6232):347-52. doi: 10.1126/science.aaa2958. Epub 2015 Mar 12.


Inhibition of CRMP2 phosphorylation repairs CNS by regulating neurotrophic and inhibitory responses.

Nagai J, Owada K, Kitamura Y, Goshima Y, Ohshima T.

Exp Neurol. 2016 Mar;277:283-95. doi: 10.1016/j.expneurol.2016.01.015. Epub 2016 Jan 18.


Meningeal cells and glia establish a permissive environment for axon regeneration after spinal cord injury in newts.

Zukor KA, Kent DT, Odelberg SJ.

Neural Dev. 2011 Jan 4;6:1. doi: 10.1186/1749-8104-6-1.


Decorin blocks scarring and cystic cavitation in acute and induces scar dissolution in chronic spinal cord wounds.

Ahmed Z, Bansal D, Tizzard K, Surey S, Esmaeili M, Gonzalez AM, Berry M, Logan A.

Neurobiol Dis. 2014 Apr;64:163-76. doi: 10.1016/j.nbd.2013.12.008. Epub 2013 Dec 31.


Hepatocyte growth factor reduces astrocytic scar formation and promotes axonal growth beyond glial scars after spinal cord injury.

Jeong SR, Kwon MJ, Lee HG, Joe EH, Lee JH, Kim SS, Suh-Kim H, Kim BG.

Exp Neurol. 2012 Jan;233(1):312-22. doi: 10.1016/j.expneurol.2011.10.021. Epub 2011 Oct 31.


Effects of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor on glial scar formation after spinal cord injury in rats.

Chung J, Kim MH, Yoon YJ, Kim KH, Park SR, Choi BH.

J Neurosurg Spine. 2014 Dec;21(6):966-73. doi: 10.3171/2014.8.SPINE131090. Epub 2014 Oct 3.


Sensory afferents regenerated into dorsal columns after spinal cord injury remain in a chronic pathophysiological state.

Tan AM, Petruska JC, Mendell LM, Levine JM.

Exp Neurol. 2007 Aug;206(2):257-68. Epub 2007 May 23.


Antisense vimentin cDNA combined with chondroitinase ABC promotes axon regeneration and functional recovery following spinal cord injury in rats.

Xia Y, Yan Y, Xia H, Zhao T, Chu W, Hu S, Feng H, Lin J.

Neurosci Lett. 2015 Mar 17;590:74-9. doi: 10.1016/j.neulet.2015.01.073. Epub 2015 Jan 29.


Kindlin-1 enhances axon growth on inhibitory chondroitin sulfate proteoglycans and promotes sensory axon regeneration.

Tan CL, Andrews MR, Kwok JC, Heintz TG, Gumy LF, Fässler R, Fawcett JW.

J Neurosci. 2012 May 23;32(21):7325-35. doi: 10.1523/JNEUROSCI.5472-11.2012.


Suppression of fibrous scarring in spinal cord injury of rat promotes long-distance regeneration of corticospinal tract axons, rescue of primary motoneurons in somatosensory cortex and significant functional recovery.

Klapka N, Hermanns S, Straten G, Masanneck C, Duis S, Hamers FP, Müller D, Zuschratter W, Müller HW.

Eur J Neurosci. 2005 Dec;22(12):3047-58.


High molecular weight hyaluronic acid limits astrocyte activation and scar formation after spinal cord injury.

Khaing ZZ, Milman BD, Vanscoy JE, Seidlits SK, Grill RJ, Schmidt CE.

J Neural Eng. 2011 Aug;8(4):046033. doi: 10.1088/1741-2560/8/4/046033. Epub 2011 Jul 14.


mRNAs and Protein Synthetic Machinery Localize into Regenerating Spinal Cord Axons When They Are Provided a Substrate That Supports Growth.

Kalinski AL, Sachdeva R, Gomes C, Lee SJ, Shah Z, Houle JD, Twiss JL.

J Neurosci. 2015 Jul 15;35(28):10357-70. doi: 10.1523/JNEUROSCI.1249-15.2015.


Decorin suppresses neurocan, brevican, phosphacan and NG2 expression and promotes axon growth across adult rat spinal cord injuries.

Davies JE, Tang X, Denning JW, Archibald SJ, Davies SJ.

Eur J Neurosci. 2004 Mar;19(5):1226-42.


Spinal cord regeneration.

Young W.

Cell Transplant. 2014;23(4-5):573-611. doi: 10.3727/096368914X678427. Review.


Sensory axon regeneration: rebuilding functional connections in the spinal cord.

Smith GM, Falone AE, Frank E.

Trends Neurosci. 2012 Mar;35(3):156-63. doi: 10.1016/j.tins.2011.10.006. Epub 2011 Nov 30. Review.


Inactivation of glycogen synthase kinase 3 promotes axonal growth and recovery in the CNS.

Dill J, Wang H, Zhou F, Li S.

J Neurosci. 2008 Sep 3;28(36):8914-28. doi: 10.1523/JNEUROSCI.1178-08.2008.

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