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Items: 1 to 20 of 108

1.

Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing.

Relling MV, Gardner EE, Sandborn WJ, Schmiegelow K, Pui CH, Yee SW, Stein CM, Carrillo M, Evans WE, Klein TE; Clinical Pharmacogenetics Implementation Consortium..

Clin Pharmacol Ther. 2011 Mar;89(3):387-91. doi: 10.1038/clpt.2010.320. Erratum in: Clin Pharmacol Ther. 2011 Dec;90(6):894.

2.

Implementation of TPMT testing.

Lennard L.

Br J Clin Pharmacol. 2014 Apr;77(4):704-14. doi: 10.1111/bcp.12226.

3.

Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine.

Evans WE, Hon YY, Bomgaars L, Coutre S, Holdsworth M, Janco R, Kalwinsky D, Keller F, Khatib Z, Margolin J, Murray J, Quinn J, Ravindranath Y, Ritchey K, Roberts W, Rogers ZR, Schiff D, Steuber C, Tucci F, Kornegay N, Krynetski EY, Relling MV.

J Clin Oncol. 2001 Apr 15;19(8):2293-301.

PMID:
11304783
4.

Possible implication of thiopurine S-methyltransferase in occurrence of infectious episodes during maintenance therapy for childhood lymphoblastic leukemia with mercaptopurine.

Dervieux T, Médard Y, Verpillat P, Guigonis V, Duval M, Lescoeur B, Suciu S, Vilmer E, Jacqz-Aigrain E.

Leukemia. 2001 Nov;15(11):1706-12.

PMID:
11681411
5.

[Monitoring of thiopurine methyltransferase and thiopurine metabolites to optimize azathioprine therapy in inflammatory bowel disease].

Gisbert JP, González-Lama Y, Maté J.

Gastroenterol Hepatol. 2006 Nov;29(9):568-83. Review. Spanish.

PMID:
17129552
6.
7.

Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy?

Sanderson J, Ansari A, Marinaki T, Duley J.

Ann Clin Biochem. 2004 Jul;41(Pt 4):294-302. Review.

PMID:
15298741
8.

Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus.

Relling MV, Hancock ML, Rivera GK, Sandlund JT, Ribeiro RC, Krynetski EY, Pui CH, Evans WE.

J Natl Cancer Inst. 1999 Dec 1;91(23):2001-8.

PMID:
10580024
9.

Next steps on the thiopurine methyltransferase 6-thioguanine nucleotide pathway.

Colletti RB.

J Pediatr Gastroenterol Nutr. 2006 Sep;43(3):282-3. No abstract available.

PMID:
16954947
10.

Identification of Patients With Variants in TPMT and Dose Reduction Reduces Hematologic Events During Thiopurine Treatment of Inflammatory Bowel Disease.

Coenen MJ, de Jong DJ, van Marrewijk CJ, Derijks LJ, Vermeulen SH, Wong DR, Klungel OH, Verbeek AL, Hooymans PM, Peters WH, te Morsche RH, Newman WG, Scheffer H, Guchelaar HJ, Franke B; TOPIC Recruitment Team..

Gastroenterology. 2015 Oct;149(4):907-17.e7. doi: 10.1053/j.gastro.2015.06.002.

PMID:
26072396
11.
12.

Monitoring of thiopurine methyltransferase activity in postsurgical patients with Crohn's disease during 1 year of treatment with azathioprine or mesalazine.

Dilger K, Schaeffeler E, Lukas M, Strauch U, Herfarth H, Müller R, Schwab M.

Ther Drug Monit. 2007 Feb;29(1):1-5.

PMID:
17304143
13.

Recent advances in the pharmacogenomics of thiopurine methyltransferase.

Coulthard SA, Hall AG.

Pharmacogenomics J. 2001;1(4):254-61. Review.

PMID:
11908768
14.

[Bone marrow depression after azathioprine. New discoveries on an old drug].

Löwhagen GB, Lindstedt G.

Lakartidningen. 2000 Feb 2;97(5):458-62. Swedish.

PMID:
10707497
15.

Pharmacogenetics during standardised initiation of thiopurine treatment in inflammatory bowel disease.

Hindorf U, Lindqvist M, Peterson C, Söderkvist P, Ström M, Hjortswang H, Pousette A, Almer S.

Gut. 2006 Oct;55(10):1423-31.

16.

Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease.

Gearry RB, Barclay ML.

J Gastroenterol Hepatol. 2005 Aug;20(8):1149-57. Review.

PMID:
16048561
17.

The impact of thiopurine s-methyltransferase polymorphism on azathioprine-induced myelotoxicity in renal transplant recipients.

Kurzawski M, Dziewanowski K, Gawrońska-Szklarz B, Domański L, Droździk M.

Ther Drug Monit. 2005 Aug;27(4):435-41.

PMID:
16044099
18.

Analytic aspects of monitoring therapy with thiopurine medications.

Armstrong VW, Shipkova M, von Ahsen N, Oellerich M.

Ther Drug Monit. 2004 Apr;26(2):220-6. Review.

PMID:
15228169
19.

Individualization of thiopurine therapy: thiopurine S-methyltransferase and beyond.

Karas-Kuzelicki N, Mlinaric-Rascan I.

Pharmacogenomics. 2009 Aug;10(8):1309-22. doi: 10.2217/pgs.09.78. Review.

PMID:
19663675
20.

Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance.

Yates CR, Krynetski EY, Loennechen T, Fessing MY, Tai HL, Pui CH, Relling MV, Evans WE.

Ann Intern Med. 1997 Apr 15;126(8):608-14.

PMID:
9103127
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