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Items: 1 to 20 of 115

1.

Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice.

Kang L, Ayala JE, Lee-Young RS, Zhang Z, James FD, Neufer PD, Pozzi A, Zutter MM, Wasserman DH.

Diabetes. 2011 Feb;60(2):416-26. doi: 10.2337/db10-1116.

2.

Matrix metalloproteinase 9 opposes diet-induced muscle insulin resistance in mice.

Kang L, Mayes WH, James FD, Bracy DP, Wasserman DH.

Diabetologia. 2014 Mar;57(3):603-13. doi: 10.1007/s00125-013-3128-1. Epub 2013 Dec 4.

3.

Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice.

Kang L, Mokshagundam S, Reuter B, Lark DS, Sneddon CC, Hennayake C, Williams AS, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH.

Diabetes. 2016 Jun;65(6):1590-600. doi: 10.2337/db15-1434. Epub 2016 Apr 5.

4.

Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance.

Williams AS, Kang L, Zheng J, Grueter C, Bracy DP, James FD, Pozzi A, Wasserman DH.

J Biol Chem. 2015 Mar 6;290(10):6546-57. doi: 10.1074/jbc.M114.615716. Epub 2015 Jan 15.

5.

Glucagon-like peptide-1 receptor knockout mice are protected from high-fat diet-induced insulin resistance.

Ayala JE, Bracy DP, James FD, Burmeister MA, Wasserman DH, Drucker DJ.

Endocrinology. 2010 Oct;151(10):4678-87. doi: 10.1210/en.2010-0289. Epub 2010 Aug 4.

6.

Heterozygous SOD2 deletion impairs glucose-stimulated insulin secretion, but not insulin action, in high-fat-fed mice.

Kang L, Dai C, Lustig ME, Bonner JS, Mayes WH, Mokshagundam S, James FD, Thompson CS, Lin CT, Perry CG, Anderson EJ, Neufer PD, Wasserman DH, Powers AC.

Diabetes. 2014 Nov;63(11):3699-710. doi: 10.2337/db13-1845. Epub 2014 Jun 19.

7.

Dietary quercetin supplementation in mice increases skeletal muscle PGC1α expression, improves mitochondrial function and attenuates insulin resistance in a time-specific manner.

Henagan TM, Lenard NR, Gettys TW, Stewart LK.

PLoS One. 2014 Feb 21;9(2):e89365. doi: 10.1371/journal.pone.0089365. eCollection 2014.

8.

Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice.

Rubel D, Frese J, Martin M, Leibnitz A, Girgert R, Miosge N, Eckes B, Müller GA, Gross O.

Matrix Biol. 2014 Feb;34:13-21. doi: 10.1016/j.matbio.2014.01.006. Epub 2014 Jan 27.

PMID:
24480069
9.

Enhanced mitochondrial superoxide scavenging does not improve muscle insulin action in the high fat-fed mouse.

Lark DS, Kang L, Lustig ME, Bonner JS, James FD, Neufer PD, Wasserman DH.

PLoS One. 2015 May 19;10(5):e0126732. doi: 10.1371/journal.pone.0126732. eCollection 2015.

10.

Hyaluronan accumulates with high-fat feeding and contributes to insulin resistance.

Kang L, Lantier L, Kennedy A, Bonner JS, Mayes WH, Bracy DP, Bookbinder LH, Hasty AH, Thompson CB, Wasserman DH.

Diabetes. 2013 Jun;62(6):1888-96. doi: 10.2337/db12-1502. Epub 2013 Jan 24.

11.

Chronic treatment with sildenafil improves energy balance and insulin action in high fat-fed conscious mice.

Ayala JE, Bracy DP, Julien BM, Rottman JN, Fueger PT, Wasserman DH.

Diabetes. 2007 Apr;56(4):1025-33. Epub 2007 Jan 17.

12.

Reduced vascular nitric oxide-cGMP signaling contributes to adipose tissue inflammation during high-fat feeding.

Handa P, Tateya S, Rizzo NO, Cheng AM, Morgan-Stevenson V, Han CY, Clowes AW, Daum G, O'Brien KD, Schwartz MW, Chait A, Kim F.

Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):2827-35. doi: 10.1161/ATVBAHA.111.236554. Epub 2011 Sep 8.

13.

Relaxin treatment reverses insulin resistance in mice fed a high-fat diet.

Bonner JS, Lantier L, Hocking KM, Kang L, Owolabi M, James FD, Bracy DP, Brophy CM, Wasserman DH.

Diabetes. 2013 Sep;62(9):3251-60. doi: 10.2337/db13-0033. Epub 2013 Jun 25.

14.

Blockade of interleukin 6 signalling ameliorates systemic insulin resistance through upregulation of glucose uptake in skeletal muscle and improves hepatic steatosis in high-fat diet fed mice.

Yamaguchi K, Nishimura T, Ishiba H, Seko Y, Okajima A, Fujii H, Tochiki N, Umemura A, Moriguchi M, Sumida Y, Mitsuyoshi H, Yasui K, Minami M, Okanoue T, Itoh Y.

Liver Int. 2015 Feb;35(2):550-61. doi: 10.1111/liv.12645. Epub 2014 Aug 12.

PMID:
25066281
15.

Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart.

Park SY, Kim HJ, Wang S, Higashimori T, Dong J, Kim YJ, Cline G, Li H, Prentki M, Shulman GI, Mitchell GA, Kim JK.

Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E30-9. Epub 2005 Feb 8.

16.

Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity.

Guo T, Jou W, Chanturiya T, Portas J, Gavrilova O, McPherron AC.

PLoS One. 2009;4(3):e4937. doi: 10.1371/journal.pone.0004937. Epub 2009 Mar 19.

17.

Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Hepatic Insulin Resistance.

Williams AS, Trefts E, Lantier L, Grueter CA, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH.

Diabetes. 2017 Feb;66(2):325-334. doi: 10.2337/db16-0484. Epub 2016 Nov 29.

18.

Insulin action in the double incretin receptor knockout mouse.

Ayala JE, Bracy DP, Hansotia T, Flock G, Seino Y, Wasserman DH, Drucker DJ.

Diabetes. 2008 Feb;57(2):288-97. Epub 2007 Oct 31.

19.

Mitochondrial-Targeted Catalase Protects Against High-Fat Diet-Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation.

Lee HY, Lee JS, Alves T, Ladiges W, Rabinovitch PS, Jurczak MJ, Choi CS, Shulman GI, Samuel VT.

Diabetes. 2017 Aug;66(8):2072-2081. doi: 10.2337/db16-1334. Epub 2017 May 5.

PMID:
28476930
20.

Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.

Terauchi Y, Takamoto I, Kubota N, Matsui J, Suzuki R, Komeda K, Hara A, Toyoda Y, Miwa I, Aizawa S, Tsutsumi S, Tsubamoto Y, Hashimoto S, Eto K, Nakamura A, Noda M, Tobe K, Aburatani H, Nagai R, Kadowaki T.

J Clin Invest. 2007 Jan;117(1):246-57.

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