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Items: 1 to 20 of 91

1.

Mutation in the βA3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat.

Zigler JS Jr, Zhang C, Grebe R, Sehrawat G, Hackler L Jr, Adhya S, Hose S, McLeod DS, Bhutto I, Barbour W, Parthasarathy G, Zack DJ, Sergeev Y, Lutty GA, Handa JT, Sinha D.

J Cell Sci. 2011 Feb 15;124(Pt 4):523-31. doi: 10.1242/jcs.078790. Epub 2011 Jan 25.

2.

Modulation of V-ATPase by βA3/A1-Crystallin in Retinal Pigment Epithelial Cells.

Valapala M, Sergeev Y, Wawrousek E, Hose S, Zigler JS Jr, Sinha D.

Adv Exp Med Biol. 2016;854:779-84. doi: 10.1007/978-3-319-17121-0_104.

PMID:
26427489
3.

Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.

Valapala M, Wilson C, Hose S, Bhutto IA, Grebe R, Dong A, Greenbaum S, Gu L, Sengupta S, Cano M, Hackett S, Xu G, Lutty GA, Dong L, Sergeev Y, Handa JT, Campochiaro P, Wawrousek E, Zigler JS Jr, Sinha D.

Autophagy. 2014 Mar;10(3):480-96. doi: 10.4161/auto.27292. Epub 2014 Jan 23.

4.

βA3/A1-crystallin: more than a lens protein.

Zigler JS Jr, Sinha D.

Prog Retin Eye Res. 2015 Jan;44:62-85. doi: 10.1016/j.preteyeres.2014.11.002. Epub 2014 Nov 13. Review.

5.

Expression of βA3/A1-crystallin in the developing and adult rat eye.

Parthasarathy G, Ma B, Zhang C, Gongora C, Samuel Zigler J Jr, Duncan MK, Sinha D.

J Mol Histol. 2011 Feb;42(1):59-69. doi: 10.1007/s10735-010-9307-1. Epub 2011 Jan 4.

6.

CRYβA3/A1-Crystallin Knockout Develops Nuclear Cataract and Causes Impaired Lysosomal Cargo Clearance and Calpain Activation.

Hegde S, Kesterson RA, Srivastava OP.

PLoS One. 2016 Feb 10;11(2):e0149027. doi: 10.1371/journal.pone.0149027. eCollection 2016.

7.

Lysosomes: Regulators of autophagy in the retinal pigmented epithelium.

Sinha D, Valapala M, Shang P, Hose S, Grebe R, Lutty GA, Zigler JS Jr, Kaarniranta K, Handa JT.

Exp Eye Res. 2016 Mar;144:46-53. doi: 10.1016/j.exer.2015.08.018. Epub 2015 Aug 28. Review.

8.

Acidification of phagosomes and degradation of rod outer segments in rat retinal pigment epithelium.

Deguchi J, Yamamoto A, Yoshimori T, Sugasawa K, Moriyama Y, Futai M, Suzuki T, Kato K, Uyama M, Tashiro Y.

Invest Ophthalmol Vis Sci. 1994 Feb;35(2):568-79.

PMID:
8113008
9.

βA3/A1-crystallin is required for proper astrocyte template formation and vascular remodeling in the retina.

Sinha D, Valapala M, Bhutto I, Patek B, Zhang C, Hose S, Yang F, Cano M, Stark WJ, Lutty GA, Zigler JS, Wawrousek EF.

Transgenic Res. 2012 Oct;21(5):1033-42. doi: 10.1007/s11248-012-9608-0. Epub 2012 Mar 17.

10.

Regulation of Phagolysosomal Digestion by Caveolin-1 of the Retinal Pigment Epithelium Is Essential for Vision.

Sethna S, Chamakkala T, Gu X, Thompson TC, Cao G, Elliott MH, Finnemann SC.

J Biol Chem. 2016 Mar 18;291(12):6494-506. doi: 10.1074/jbc.M115.687004. Epub 2016 Jan 26.

11.
12.

βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis.

Ma B, Sen T, Asnaghi L, Valapala M, Yang F, Hose S, McLeod DS, Lu Y, Eberhart C, Zigler JS Jr, Sinha D.

Cell Death Dis. 2011 Oct 13;2:e217. doi: 10.1038/cddis.2011.100.

13.

βA3/A1-crystallin is a critical mediator of STAT3 signaling in optic nerve astrocytes.

Valapala M, Edwards M, Hose S, Hu J, Wawrousek E, Lutty GA, Zigler JS Jr, Qian J, Sinha D.

Sci Rep. 2015 Mar 4;5:8755. doi: 10.1038/srep08755.

14.

Phagosome maturation during endosome interaction revealed by partial rhodopsin processing in retinal pigment epithelium.

Wavre-Shapton ST, Meschede IP, Seabra MC, Futter CE.

J Cell Sci. 2014 Sep 1;127(Pt 17):3852-61. doi: 10.1242/jcs.154757. Epub 2014 Jul 29.

15.

Live-Cell Imaging of Phagosome Motility in Primary Mouse RPE Cells.

Hazim R, Jiang M, Esteve-Rudd J, Diemer T, Lopes VS, Williams DS.

Adv Exp Med Biol. 2016;854:751-5. doi: 10.1007/978-3-319-17121-0_100.

PMID:
26427485
16.

Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease).

Wavre-Shapton ST, Calvi AA, Turmaine M, Seabra MC, Cutler DF, Futter CE, Mitchison HM.

Hum Mol Genet. 2015 Dec 15;24(24):7060-74. doi: 10.1093/hmg/ddv406. Epub 2015 Oct 8.

17.

Rescue of compromised lysosomes enhances degradation of photoreceptor outer segments and reduces lipofuscin-like autofluorescence in retinal pigmented epithelial cells.

Guha S, Liu J, Baltazar G, Laties AM, Mitchell CH.

Adv Exp Med Biol. 2014;801:105-11. doi: 10.1007/978-1-4614-3209-8_14. Review.

18.

Phagocytosis of outer segments by retinal pigment epithelium: phagosome-lysosome interaction.

Bosch E, Horwitz J, Bok D.

J Histochem Cytochem. 1993 Feb;41(2):253-63.

PMID:
8419462
19.

betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development.

Sinha D, Klise A, Sergeev Y, Hose S, Bhutto IA, Hackler L Jr, Malpic-Llanos T, Samtani S, Grebe R, Goldberg MF, Hejtmancik JF, Nath A, Zack DJ, Fariss RN, McLeod DS, Sundin O, Broman KW, Lutty GA, Zigler JS Jr.

Mol Cell Neurosci. 2008 Jan;37(1):85-95. Epub 2007 Aug 31.

20.

Age-related degradation of betaA3/A1-crystallin in human lenses.

Srivastava OP, Srivastava K, Harrington V.

Biochem Biophys Res Commun. 1999 May 19;258(3):632-8.

PMID:
10329436

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